The Effect of Glomerular Filtration Rate and Troponin on the Prognosis of Patients with COVID-19

Abstract

Aim: During the pandemic, clinicians have generally focused on treating respiratory tract infections. It determined that all organs are affected over time, especially the heart and kidneys, and the clinic deteriorates rapidly. We aimed to determine whether serial glomerular filtration rate and troponin tests would predict prognosis in patients with COVID-19. Material and Method: One hundred seven patients diagnosed with COVID-19 were included in this study. We evaluated in-hospital mortality based on the presence and absence of troponin elevation and renal dysfunction at patients’ first and last examinations. We also investigated the correlation of both troponin elevation and renal dysfunction with age, pneumonia severity, and each other. Results: Most surviving patients were female, and the average age was younger than the other group. The most common comorbidity was hypertension. It was observed that the patients with a high last glomerular filtration rate, low last troponin test, and low pneumonia severity survived. The most important factors affecting the prognosis were the severity of pneumonia and the last glomerular filtration rate. Conclusion: Based on the conclusion from this study, the prognosis of patients with rapidly worsening cardiac and renal function can deteriorate. Those tests require close monitoring.

Keywords

• COVID-19
• glomerular filtration rate
• troponin
• pneumonia severity; prognosis

References

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