Evaluation of Bacteria Isolated from Endotracheal Aspirates of Patients in Intensive Care Units: A Single-Centre Retrospective Study

Year 2025, Volume: 15 Issue: 1, 26 - 31, 30.04.2025

Cihan Semet

Abstract

Aim: This study aims to analyze the bacteriological profile and antibiotic susceptibility patterns of isolates from endotracheal aspirates (ETAs) of intensive care units (ICUs) patients to provide data for combating ventilator-associated pneumonia (VAP) and other nosocomial infections.
Material and Method: A retrospective study of ETA samples from ICU patients (January-December 2022) was conducted. Bacteria were identified and tested for antibiotic susceptibility according to EUCAST criteria.
Results: Among 263 isolates, predominant gram-negative bacteria were Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella spp., gram-positive bacteria included Staphylococcus epidermidis and Staphylococcus aureus. High resistance was noted in Acinetobacter baumannii to ciprofloxacin (96.4%) and piperacillin-tazobactam (97.3%). Staphylococcus epidermidis showed resistance to oxacillin (66.6%) but none to vancomycin or linezolid.
Conclusion: The prevalence of multidrug-resistant pathogens in ETA cultures emphasises the importance of improved surveillance, antimicrobial stewardship and infection control in ICUs.

Keywords

ventilator-associated pneumonia , endotracheal aspirates , antibiotic resistance

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