Research Article

The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life

Volume: 15 Number: 1 April 30, 2025
EN

The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life

Abstract

Aim: This study aimed to investigate the relationship between knee osteoarthritis (OA) severity and key clinical factors such as muscle strength, proprioception, and quality of life (QoL) in individuals with bilateral knee OA. Material and Method: A cross-sectional observational study was conducted with 40 participants diagnosed with bilateral knee OA. Isometric quadriceps and hamstring muscle strength were measured using a hand-held dynamometer. Proprioception was assessed using a digital inclinometer during knee flexion at 30° and 60°. Osteoarthritis severity was determined using the Kellgren-Lawrence classification and the Lequesne Algofunctional Knee Index, while QoL and functional status were evaluated using the WOMAC Index. Results: As OA severity increased, significant increases were observed in WOMAC pain, stiffness, and physical function scores, indicating worse outcomes in QoL (p<0.005). Proprioception was notably impaired at 60° of knee flexion in the non-dominant leg as OA grade increased. At the same time, no significant muscle strength decline in the quadriceps and hamstrings was observed across OA grades (p>0.005). Conclusion: OA severity is closely associated with worse QoL outcomes, particularly in pain and physical function, but not consistently with muscle strength. These findings highlight the need for tailored rehabilitation programs that focus on improving proprioception and pain management in OA patients.

Keywords

References

  1. 1. Muraki S, Akune T, Oka H, et al. Association of radiographic and symptomatic knee osteoarthritis with health-related quality of life in a population-based cohort study in Japan: the ROA study. Osteoarthritis and cartilage. 2010;18:1227–34.
  2. 2. Park HM, Kim HS, Lee YJ. Knee osteoarthritis and its association with mental health and health‐related quality of life:a nationwide cross‐sectional study. Geriatrics & Gerontology International. 2020;20:379–83.
  3. 3. Ruhdorfer A, Wirth W, Hitzl W, Nevitt M, Eckstein F, Investigators OI. Association of thigh muscle strength with knee symptoms and radiographic disease stage of osteoarthritis: data from the Osteoarthritis Initiative. Arthritis care & research.2014;66:1344–53.
  4. 4. Khalaj N, Abu Osman NA, Mokhtar AH, Mehdikhani M, Wan Abas WAB. Balance and risk of fall in individuals with bilateral mild and moderate knee osteoarthritis. PloS one. 2014;9:e92270.
  5. 5. Özüdoğru A, Gelecek N. Effects of closed and open kinetic chain exercises on pain, muscle strength, function, and quality of life in patients with knee osteoarthritis. Revista da Associação Médica Brasileira. 2023;69:e20230164.
  6. 6. Bennell KL, Hinman RS, Metcalf BR, et al. Relationship of knee joint proprioception to pain and disability in individuals with knee osteoarthritis. Journal of orthopaedic research. 2003;21:792–7.
  7. 7. Van der Esch M, Steultjens M, Harlaar J, Knol D, Lems W, Dekker J. Joint proprioception, muscle strength, and functional ability in patients with osteoarthritis of the knee. Arthritis Care & Research: Official Journal of the American College of Rheumatology. 2007;57:787–93.
  8. 8. Pai YC, Rymer WZ, Chang RW, Sharma L. Effect of age and osteoarthritis on knee proprioception. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology. 1997;40:2260–5.

Details

Primary Language

English

Subjects

Physical Medicine and Rehabilitation

Journal Section

Research Article

Publication Date

April 30, 2025

Submission Date

November 1, 2024

Acceptance Date

March 13, 2025

Published in Issue

Year 2025 Volume: 15 Number: 1

APA
Akaras, E., Akçay, İ. H., Tayfun, A., Baygutalp, F., & Yağız, G. (2025). The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life. Kafkas Journal of Medical Sciences, 15(1), 44-51. https://izlik.org/JA69TD29KW
AMA
1.Akaras E, Akçay İH, Tayfun A, Baygutalp F, Yağız G. The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life. Kafkas Journal of Medical Sciences. 2025;15(1):44-51. https://izlik.org/JA69TD29KW
Chicago
Akaras, Esedullah, İbrahim Halil Akçay, Aliekber Tayfun, Fatih Baygutalp, and Gökhan Yağız. 2025. “The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life”. Kafkas Journal of Medical Sciences 15 (1): 44-51. https://izlik.org/JA69TD29KW.
EndNote
Akaras E, Akçay İH, Tayfun A, Baygutalp F, Yağız G (April 1, 2025) The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life. Kafkas Journal of Medical Sciences 15 1 44–51.
IEEE
[1]E. Akaras, İ. H. Akçay, A. Tayfun, F. Baygutalp, and G. Yağız, “The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life”, Kafkas Journal of Medical Sciences, vol. 15, no. 1, pp. 44–51, Apr. 2025, [Online]. Available: https://izlik.org/JA69TD29KW
ISNAD
Akaras, Esedullah - Akçay, İbrahim Halil - Tayfun, Aliekber - Baygutalp, Fatih - Yağız, Gökhan. “The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life”. Kafkas Journal of Medical Sciences 15/1 (April 1, 2025): 44-51. https://izlik.org/JA69TD29KW.
JAMA
1.Akaras E, Akçay İH, Tayfun A, Baygutalp F, Yağız G. The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life. Kafkas Journal of Medical Sciences. 2025;15:44–51.
MLA
Akaras, Esedullah, et al. “The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life”. Kafkas Journal of Medical Sciences, vol. 15, no. 1, Apr. 2025, pp. 44-51, https://izlik.org/JA69TD29KW.
Vancouver
1.Esedullah Akaras, İbrahim Halil Akçay, Aliekber Tayfun, Fatih Baygutalp, Gökhan Yağız. The Relationship Between Knee Osteoarthritis Severity, Muscle Strength, Proprioception, and Quality of Life. Kafkas Journal of Medical Sciences [Internet]. 2025 Apr. 1;15(1):44-51. Available from: https://izlik.org/JA69TD29KW