Case Report
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Hepatitis C Coinfection in a Patient with Chronic Hepatitis B

Year 2026, Volume: 16 Issue: 1, 124 - 125, 19.03.2026
https://izlik.org/JA77LL95PJ

Abstract

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are important causes of deaths due to chronic liver disease, cirrhosis and hepatocellular carcinoma. Both viruses can cause chronic disease without causing an acute and noisy disease picture. When HBV/HCV coinfection is detected, it accelerates disease progression and increases the risk of cirrhosis and hepatocellular carcinoma compared to monoinfection. In this case report, anti-HCV positivity detected in outpatient clinic controls of an asymptomatic chronic hepatitis B patient and the subsequent treatment and follow-up of the patient are presented.

References

  • 1. Aygen B, Çelen MK, Köksal İ, Tosun S, Karabay O, Yamazhan T, et al. The prevalence and epidemiological characteristics of hepatitis B virus and hepatitis C virus coinfection in Turkey. Turkiye Klinikleri J Med Sci. 2013;33(5):1245–1249. https://doi.org/10.5336/medsci.2012-32319
  • 2. Konstantinou D, Deutsch M. The spectrum of HBV/HCV coinfection: epidemiology, clinical characteristics, viralinteractions and management. Ann Gastroenterol. 2015;28(2):221–228.
  • 3. Marot A, Belaid A, Orlent H, Sersté T, Michielsen P, Colle I, et al. Characteristics of patients with hepatitis B virus and hepatitis C virus dual infection in a Western European country: Comparison with monoinfected patients. Clin Res Hepatol Gastroenterol. 2017;41(6):656–663. https://doi.org/10.1016/j.clinre.2017.05.003
  • 4. Pol S, Haour G, Fontaine H, Dorival C, Petrov-Sanchez V, Bourliere M, et al. The negative impact of HBV/HCV coinfection on cirrhosis and its consequences. Aliment Pharmacol Ther. 2017;46(11-12):1054–1060. https://doi.org/10.1111/apt.14352
  • 5. Yang WT, Wu LW, Tseng TC, Chen CL, Yang HC, Su TH, et al. Hepatitis B surface antigen loss and hepatocellular carcinoma development in patients with dual hepatitis B and C infection. Medicine (Baltimore). 2016;95(10):e2995. https://doi.org/10.1097/MD.0000000000002995
  • 6. Fong TL, Di Bisceglie AM, Waggoner JG, Banks SM, Hoofnagle JH. The significance of antibodies to the hepatitis C virus in patients with chronic hepatitis B. Hepatology. 1991;14:64–67. https://doi.org/10.1002/hep.1840140111
  • 7. Cardoso C, Alves AL, Augusto F, Freire R, Quintana C, Gonçalves M, et al. Occult hepatitis B infection in Portuguese patients with chronic hepatitis C liver disease: prevalence and clinical significance. Eur J Gastroenterol Hepatol. 2013;25:142–146. https://doi.org/10.1097/MEG.0b013e328359fe54

Year 2026, Volume: 16 Issue: 1, 124 - 125, 19.03.2026
https://izlik.org/JA77LL95PJ

Abstract

References

  • 1. Aygen B, Çelen MK, Köksal İ, Tosun S, Karabay O, Yamazhan T, et al. The prevalence and epidemiological characteristics of hepatitis B virus and hepatitis C virus coinfection in Turkey. Turkiye Klinikleri J Med Sci. 2013;33(5):1245–1249. https://doi.org/10.5336/medsci.2012-32319
  • 2. Konstantinou D, Deutsch M. The spectrum of HBV/HCV coinfection: epidemiology, clinical characteristics, viralinteractions and management. Ann Gastroenterol. 2015;28(2):221–228.
  • 3. Marot A, Belaid A, Orlent H, Sersté T, Michielsen P, Colle I, et al. Characteristics of patients with hepatitis B virus and hepatitis C virus dual infection in a Western European country: Comparison with monoinfected patients. Clin Res Hepatol Gastroenterol. 2017;41(6):656–663. https://doi.org/10.1016/j.clinre.2017.05.003
  • 4. Pol S, Haour G, Fontaine H, Dorival C, Petrov-Sanchez V, Bourliere M, et al. The negative impact of HBV/HCV coinfection on cirrhosis and its consequences. Aliment Pharmacol Ther. 2017;46(11-12):1054–1060. https://doi.org/10.1111/apt.14352
  • 5. Yang WT, Wu LW, Tseng TC, Chen CL, Yang HC, Su TH, et al. Hepatitis B surface antigen loss and hepatocellular carcinoma development in patients with dual hepatitis B and C infection. Medicine (Baltimore). 2016;95(10):e2995. https://doi.org/10.1097/MD.0000000000002995
  • 6. Fong TL, Di Bisceglie AM, Waggoner JG, Banks SM, Hoofnagle JH. The significance of antibodies to the hepatitis C virus in patients with chronic hepatitis B. Hepatology. 1991;14:64–67. https://doi.org/10.1002/hep.1840140111
  • 7. Cardoso C, Alves AL, Augusto F, Freire R, Quintana C, Gonçalves M, et al. Occult hepatitis B infection in Portuguese patients with chronic hepatitis C liver disease: prevalence and clinical significance. Eur J Gastroenterol Hepatol. 2013;25:142–146. https://doi.org/10.1097/MEG.0b013e328359fe54
There are 7 citations in total.

Details

Primary Language English
Subjects Medical Infection Agents
Journal Section Case Report
Authors

Mehmet Samet Demirel

Submission Date May 11, 2025
Acceptance Date September 12, 2025
Publication Date March 19, 2026
IZ https://izlik.org/JA77LL95PJ
Published in Issue Year 2026 Volume: 16 Issue: 1

Cite

APA Demirel, M. S. (2026). Hepatitis C Coinfection in a Patient with Chronic Hepatitis B. Kafkas Journal of Medical Sciences, 16(1), 124-125. https://izlik.org/JA77LL95PJ
AMA 1.Demirel MS. Hepatitis C Coinfection in a Patient with Chronic Hepatitis B. Kafkas Journal of Medical Sciences. 2026;16(1):124-125. https://izlik.org/JA77LL95PJ
Chicago Demirel, Mehmet Samet. 2026. “Hepatitis C Coinfection in a Patient With Chronic Hepatitis B”. Kafkas Journal of Medical Sciences 16 (1): 124-25. https://izlik.org/JA77LL95PJ.
EndNote Demirel MS (March 1, 2026) Hepatitis C Coinfection in a Patient with Chronic Hepatitis B. Kafkas Journal of Medical Sciences 16 1 124–125.
IEEE [1]M. S. Demirel, “Hepatitis C Coinfection in a Patient with Chronic Hepatitis B”, Kafkas Journal of Medical Sciences, vol. 16, no. 1, pp. 124–125, Mar. 2026, [Online]. Available: https://izlik.org/JA77LL95PJ
ISNAD Demirel, Mehmet Samet. “Hepatitis C Coinfection in a Patient With Chronic Hepatitis B”. Kafkas Journal of Medical Sciences 16/1 (March 1, 2026): 124-125. https://izlik.org/JA77LL95PJ.
JAMA 1.Demirel MS. Hepatitis C Coinfection in a Patient with Chronic Hepatitis B. Kafkas Journal of Medical Sciences. 2026;16:124–125.
MLA Demirel, Mehmet Samet. “Hepatitis C Coinfection in a Patient With Chronic Hepatitis B”. Kafkas Journal of Medical Sciences, vol. 16, no. 1, Mar. 2026, pp. 124-5, https://izlik.org/JA77LL95PJ.
Vancouver 1.Mehmet Samet Demirel. Hepatitis C Coinfection in a Patient with Chronic Hepatitis B. Kafkas Journal of Medical Sciences [Internet]. 2026 Mar. 1;16(1):124-5. Available from: https://izlik.org/JA77LL95PJ