A case presentation of intracardiac thrombus formation and development of massive pulmonary embolism following brucella infection
Abstract
Brucella infection can lead to vascular complications such as intracardiac
thrombus. In this case, we presented a case of acute pulmonary
embolism due to right atrial thrombus secondary to brucella infection.
A 74-year-old male patient presented with complaints of shortness
of breath and palpitations. He exhibited hypotension and tachycardia
in vital signs, along with hypoxia and hypocarbia in laboratory
parameters. The patient had a diagnosis of brucella and under active
medical treatment. Transthoracic echocardiography revealed a
worm-like hyperechoic intracavitary mass in the right atrium which
has rough contours and synchronously move with adjacent heart
wall during heart cyles. The right atrium and right ventricle were
dilated. Computed tomography showed a hypodense lesion consistent
with embolism in the left main pulmonary artery. Due to hemodynamic
instability and the development of shock, the patient
received thrombolytic therapy. Following stabilization of vital signs,
the patient was discharged smoothly on vitamin K antagonist (VKA)
therapy.
References
- 1. Sharifi M, Bay C, Skrocki L, Rahimi F, Mehdipour M; MOPETT Investigators. Moderate pulmonary embolism treated with thrombolysis (from the “MOPETT” Trial). Am J Cardiol 2013;111:273-277.
- 2. Wang C, Zhai Z, Yang Y, Wu Q, Cheng Z, Liang L et al. Efficacy and safety of low dose recombinant tissue-type plasminogen activator for the treatment of acute pulmonary thromboembolism: a randomized, multicenter, controlled trial. Chest 2010;137:254262.
- 3. Colmenero JD,Reguera JM,Martos F,Sánchez-De-Mora D,Delgado M,Causse M,et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Clin Infect Dis. 1996;23(6):1340–6.
- 4. Rose PS, Punjabi NM, Pearse DB. Treatment of right heart thromboemboli. Chest. 2002;121:806-14
Abstract
References
- 1. Sharifi M, Bay C, Skrocki L, Rahimi F, Mehdipour M; MOPETT Investigators. Moderate pulmonary embolism treated with thrombolysis (from the “MOPETT” Trial). Am J Cardiol 2013;111:273-277.
- 2. Wang C, Zhai Z, Yang Y, Wu Q, Cheng Z, Liang L et al. Efficacy and safety of low dose recombinant tissue-type plasminogen activator for the treatment of acute pulmonary thromboembolism: a randomized, multicenter, controlled trial. Chest 2010;137:254262.
- 3. Colmenero JD,Reguera JM,Martos F,Sánchez-De-Mora D,Delgado M,Causse M,et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Clin Infect Dis. 1996;23(6):1340–6.
- 4. Rose PS, Punjabi NM, Pearse DB. Treatment of right heart thromboemboli. Chest. 2002;121:806-14
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences (Other) |
| Journal Section | Case Report |
| Authors | |
| Submission Date | February 19, 2025 |
| Acceptance Date | March 10, 2026 |
| Publication Date | March 19, 2026 |
| IZ | https://izlik.org/JA77RJ88TY |
| Published in Issue | Year 2026 Volume: 16 Issue: 1 |