Platelet to Lymphocyte Ratio and Acute Appendicitis
Abstract
Aim: Acute appendicitis (AA) is a frequent
condition for general surgery practice. However, sometimes there may be
difficulties in accurate diagnosis. The aim of this study is to research
the predictive value of platelet to lymphocyte ratio (PLR) in diagnosis
of AA.
Material and Method: Hospital records were investigated
retrospectively for 569 patients who underwent operation for AA
diagnosis. According to postoperative histopathological examination of
specimens, patients were divided into two groups: acute appendicitis
group (G1) and normal appendix group (G2). Demographic analyses and PLR
calculations on hospital admission were compared intergroup. Results:
There were 475 patients in G1 whereas 94 in G2. The cut-off value of PLR
for diagnosis of AA was 136.5 (p=0.036). The sensitivity and
specificity were 56.3% and 55.3% respectively. Positive predictive value
and negative predictive value were found as 86.2% and 19.6%
respectively.
Conclusion: PLR may be a valuable parameter supporting clinical evaluation for diagnosis and management of AA.
Keywords
References
- 1. Fitz RH. Perforating inflammation of the vermiform appendix, with special reference to its early diagnosis and treatment. Trans Assoc Am Physicians 1886;1:107–44.
- 2. Andersson RE. The role of antibiotic therapy in management of acute appendicitis. Curr Infect Dis Rep 2013;15(1):10–3.
- 3. Maa J, Kirkwood KS. The appendix. In: Townsend CM (ed). Sabiston Textbook of Surgery 19th edition, Sounders Elsevier Inc. Philadelphia 2012:1279–93.
- 4. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med 1986;15(5):557–64.
- 5. Lintula H, Kokki H, Pulkkinen J, Kettunen R, Gröhn O, Eskelinen M. Diagnostic score in acute appendicitis. Validation of a diagnostic score (Lintula score) for adults with suspected appendicitis. Langenbecks Arch Surg 2010;395:495–500.
- 6. Eskelinen M, Ikonen J, Lipponen P. Sex-specific diagnostic scores for acute appendicitis. Scand J Gastroenterol 1994;29(1):59–66.
- 7. Markar SR, Karthikesalingman A, Falzon A, Kan Y. The diagnostic value of neutrophil: lymphocyte ratio in adults with suspected acute appendicitis. Acta Chir Belg 2010;110(5):543–7.
- 8. Yazici M, Ozkisacik S, Oztan OM, Gursoy H. Neutrophil/ lymphocyte ratio in the diagnosis of childhood appendicitis. Turk J Pediatr 2010;52:400–3.
Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Research Article
Authors
Şahin Kahramanca
*
Türkiye
Gülay Özgehan
This is me
Türkiye
Oskay Kaya
This is me
Türkiye
Tevfik Hadi Küçükpınar
This is me
Türkiye
Hülagü Kargıcı
This is me
Türkiye
Mehmet Fatih Avşar
This is me
Türkiye
Publication Date
August 1, 2017
Submission Date
March 29, 2016
Acceptance Date
May 31, 2017
Published in Issue
Year 2017 Volume: 7 Number: 2