Local Bleomycin Treatment in a Newborn with Axillary Lymphangioma: A Case Report

Abstract

Cystic lymphangioma usually develops in the neck and axilla, while lesser breast tissue, abdomen, mediastinum, orbita, parathyroid and extremities can also be seen. In recent years, it has been reported that bleomycin and picibanil (OK-432) sclerotherapy treatments have been successful results in the treatment of lymphangioma. In this article, we presented a case of bleomycin treatment in a mass after axillary lymphangiomatous lesions were diagnosed at delivery at the end of pregnancy

Keywords

• axillary lymphangioma; newborn; bleomycin treatment

Aksiller Lenfanjiomu Olan Bir Yenidoğanda Lokal Bleomisin Tedavisi: Olgu Sunumu

Abstract

Kistik lenfanjiom, genellikle boyun ve aksilla bölgesinde ortaya çıkarken, daha az oranda meme dokusu, abdomen, mediasten, orbita, paratiroid ve ekstremitelerde de görülebilir. Son yıllarda lenfanjiom tedavisinde bleomisin ve picibanil (OK-432) sklerozan tedavi uygulamaları ile başarılı sonuçlar alındığı bildirilmektedir. Bu yazıda hastanemizde takipli olmayan gebelik sonucunda doğumda aksiller lenfangiom tanısı konulduktan sonra kitle içine bleomisin tedavisi uygulanan bir olgu sunulmuştur. 

Keywords

• aksiller lenfanjiom; yenidoğan; bleomisin tedavisi

References

1. 1. Stringel G. Hemangiomas and lymphangiomas. In: Aschraft KWH, ed. Pediatric Surgery. Phidelphia:1990:802–22. 2. Bhattacharyya NC, Yadav K, Mitra SK, Pathak IC. Lymphangiomas in children. Aust N Z J Surg 1981;51(3):296– 3. Bill AH, Jr. Sumner DS. A Unified concept of lymphangioma and cystic hygroma. Surg Gynecol Obstet 1965;120:79–86. 4. Yoo JC, Ahn Y, Lim YS, Hah JH, Kwon TK, Sung MW, et al. OK-432 sclerotherapy in head and neck lymphangiomas: long-term follow-up result. Otolaryngol Head Neck Surg 2009;140:120–3. 5. Sanlialp I, Karnak I, Tanyel FC, Senocak ME, Büyükpamukçu N. Sclerotherapy for lymphangioma in children. Int J Pediatr Otorhinolaryngol 2003;67:795–800. 6. Ameh EA, Nmadu PT. Cervical cystic hygroma: pre-, intra-, and post-operative morbidity and mortality in Zaria, Nigeria. Pediatr Surg Int 2001;17:342–3. 7. Sung MW, Lee DW, Kim DY, Lee SJ, Hwang CH, Park SW, et al. Sclerotherapy with picibanil (OK-432)for congenital lymphatic malformation in the head and neck. Laryngoscope 2001;111:1430–3. 8. Mikovic Z, Simic R, Egic A, Opincal TS, Koprivsek K, Stanojevic D, et al. Intrauterine treatment of large fetal neck lymphangioma with OK-432. Fetal Diagn Ther 2009;26:102. 9. Adejuyigbe O, Abubakar AM, Sowande OA, Olayinka OS, Uba AF. Experience with anorectal malformations in Ile-Ife, Nigeria. Pediatr Surg Int 2004;20:855–8. 10. Okada A, Kubota A, Fukuzawa M, Imura K, Kamata S. Injection of bleomycin as a primary therapy of cystic lymphangioma. J Pediatr Surg 1992;27:440–3. 11. Orford J, Barker A, Thonell S, King P, Murphy J. Bleomycin therapy for cystic hygroma. J Pediatr Surg 1995;30(9):128.