A Retrospective Analysis of Renal Transplantation Patients: A Single Center Experience

Year 2023, Volume: 13 Issue: 2, 139 - 143, 25.08.2023

Tamer Selen Ebru Gök Oğuz Gülay Ulusal Okyay Hatice Şahin Elif Kahraman Güner Fatma Ayerden Ebinç Kadir Gökhan Atılgan Mehmet Deniz Aylı

Abstract

Aim: In this study, we aimed to present demographic characteristics of the patients having undergone renal transplantation in our hospital between February 2017 and September 2020, to convey the experience of cadaver and living donor renal transplantation in our center, and to reveal the causes of allograft dysfunction in late posttransplant follow-ups.
Material and Method: The study included 25 patients having undergone renal transplantation in our hospital and were followed up in the nephrology clinic between February 2017 and September 2020. Then, we retrospectively analyzed their demographic characteristics, clinical and laboratory findings, transplantation types, kidney donor characteristics, renal failure etiologies, pre-transplant dialysis modalities, post-transplant complications, rejection attacks, graft loss, and causes of mortalities.
Results: The mean follow-up period of 25 renal transplant patients (17 males and 8 females with a mean age of 46.96±2.67 years) was 26.28±2.76 months. While living transplantation was performed in 16 patients, the others received cadaveric renal transplants. Five patients underwent pre-emptive renal transplantation, and three were recruited for transplant for the second time. The underlying cause of chronic kidney disease was unknown in 24% of the patients (first), while vesicoureteral reflux (VUR) and diabetes were the primary causes of the disease in 16% (second). The most prevalent cause of temporary or permanent impairment in allograft functions was urinary tract infection with 42.8%. It was more common in female patients (25%) and patients with a diagnosis of VUR (20%).
Conclusion: Overall, our findings documented that urinary system infections are common following renal transplantation, which brings adverse effects on allograft functions. VUR-led renal failure and female gender are among the factors that facilitate urinary system infection.

Keywords

renal transplantation, kidney function tests, urinary tract infection

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