The White Blood Cell Count to Mean Platelet Volume Ratio (WMR) is Associated With Syntax Score in Patients With ST-Segment Elevation Myocardial Infarction

Year 2023, Volume: 13 Issue: 2, 173 - 178, 25.08.2023

Muammer Karakayalı Timor Omar İnanç Artaç İbrahim Rencüzoğulları Yavuz Karabağ Şerif Hamideyin Mehmet Altunova

Abstract

Background: ST-segment elevation myocardial infarction (STEMI) is the most common reason for mortality worldwide. Scoring systems such as Syntax score plays a significant role in risk stratification in these patients. Besides, as a simple and easily applicable marker, white blood cell count to mean platelet volume ratio (WMR), which could play a vital role in identifying risky patients, has emerged as an indicator of inflammation in atherosclerotic disease. In the current study, we aimed to investigate the predictive role of WMR for Syntax score in patients with STEMI.
Material and Method: Demographics, comorbidities, and laboratory results on the admission of hospitalized 335 patients with STEMI were analyzed. The study population was divided into two groups according to the syntax score median of the study population (Syntax score median=19). Findings were compared between Syntax score <19 and Syntax score ≥19 groups.
Results: The Pearson correlation value between WMR and Syntax score was 0.415 (p<0.001). One hundred and sixty four patients were assigned to the Syntax score <19 group, 171 patients were designated as Syntax score ≥19 group. White blood cell count to mean platelet volume ratio was significantly higher in the Syntax score ≥19 group than the Syntax score <19 group [median (IQR), 1.56 (1.28–1.81) vs 1.32 (1.16–1.5), p<0.001]. White blood cell count to mean platelet volume ratio was an independent predictor according to multivariate analysis [Odds ratio (95% CI), 1.26 (1.08–1.47), p=0.002].
Conclusion: In patients with STEMI, WMR is significantly correlated with high syntax score. It could provide supportive data for early risk stratification and optimized approach. Consequently, therapeutic methods may be wellplanned to avoid a poor outcome in these patients.

Keywords

ST-segment elevation miyocardial infarction, syntax score, white blood cell, mean platelet volume

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