Retrospective Analysis of Patients Admitted to Physical Medicine and Rehabilitation Outpatient Clinics with Osteoarticular Findings and Diagnosed with Brucellosis

Year 2024, Volume: 14 Issue: 3, 212 - 216, 31.12.2024

Esra Şahingöz Bakırcı , Gülseren Demir Karakılıç , Ferda Surel , Tuğba Alışık

Abstract

Aim: In endemic regions, we aimed to consider Brucella infection in the differential diagnosis of musculoskeletal manifestations and to emphasize the diversity of presentation.
Material and Method: Our study has a retrospective design. Between 01.01.2020 and 01.01.2024, patients who applied to the physical therapy and rehabilitation department of a secondstage public hospital located in a region where brucella infection is endemic and were diagnosed with brucellosis with osteoarticular findings were included in our study. Demographic data, complaints at presentation, musculoskeletal examination findings, Brucella serology tests, liver function tests, complete blood counts, sedimentation rate (ESR) and C-reactive protein (CRP) levels, and related musculoskeletal imaging data were recorded.
Results: 47 patients were enrolled in the study. 68.1% (32/47) of the patients were male, while 31.9% (15/47) were female. The average age of the patients was 44.43±15.47 years. Joint pain and low back pain were the predominant symptoms observed in the majority of cases; the most common types of involvement were arthralgia (46.8%), sacroiliitis (19.1%), spondylodiscitis (14.9%) and monoarthritis (14.9%). We found elevated CRP in 48.93%, elevated ESR in 27.65%, leukocytosis in 14.89%, leukopenia in 8.51%, anemia in 31.91%, elevated ALT in 12.76% and elevated AST in 10.63%.
Conclusion: Brucellosis may present with various musculoskeletal findings. Considering Brucella infection in the differential diagnosis is crucial for preventing potential complications through prompt diagnosis and treatment in patients presenting with musculoskeletal symptoms, particularly in endemic areas.

Keywords

arthritis, brucella, sacroiliitis, spondylodiscitis

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