A Detailed Histopathological Research on Myxobolus cerebralis in Rainbow Trout Tissues
Abstract
The causative agent of whirling disease, Myxobolus cerebralis, has a negative impact on salmonid fish and causes significant economic losses. Infected specimens of rainbow trout (Oncorhynchus mykiss) exhibiting clinical signs of whirling disease were sampled and subjected to a thorough histopathological examination in this study. The results showed M. cerebralis spores in brain, spleen, and gill tissues, with notable pathological changes such as inflammation, necrosis, and cyst formation. The study details the progression of M.cerebralis infections, highlighting significant tissue damage and immune responses in the host. The results demonstrate the importance of identifying the pathogen with histopathological methods to understand the impacts on fish health and provide insight into the host tissue response.
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References
- Akram, N., El-Matbouli, M., and Saleh, M. (2023). The immune response to the myxozoan parasite Myxobolus cerebralis in salmonids: A review on whirling disease. International Journal of Molecular Sciences, 24(24), 17392.
- Antonio, D. B., El-Matbouli, M., and Hedrick, R. P. (1999). Detection of early developmental stages of Myxobolus cerebralis in fish and tubificid oligochaete hosts by in situ hybridization. Parasitology Research, 85, 942-944.
- Antonio, D. B., Andree, K., McDowell, T. S., and Hedrick, R. P. (1998). Detection of Myxobolus cerebralis in rainbow trout and oligochaete tissues by using a nonradioactive in situ hybridization (ISH) protocol. Journal of Aquatic Animal Health, 10(4), 338-347.
- Arsan, E. L., Atkinson, S. D., Hallett, S. L., Meyers, T., and Bartholomew, J. L. (2007). Expanded geographical distribution of Myxobolus cerebralis: first detections from Alaska. Journal of Fish Diseases, 30(8), 483-491.
- Baldwin, T. J., Vincent, E. R., Silflow, R. M., and Stanek, D. (2000). Myxobolus cerebralis infection in rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta) exposed under natural stream conditions. Journal of Veterinary Diagnostic Investigation, 12(4), 312-321.
- Blazer, V. S., Densmore, C. L., Schill, W. B., Cartwright, D. D., and Page, S. J. (2004). Comparative susceptibility of Atlantic salmon, lake trout and rainbow trout to Myxobolus cerebralis in controlled laboratory exposures. Diseases of Aquatic Organisms, 58(1), 27-34.
- Dar, S. A., Kaur, H., and Chishti, M. Z. (2017). First record of myxozoan parasites from fresh water fishes of Jammu and Kashmir and their pathogenecity. Microbial pathogenesis, 105, 138-144.
- El-Matbouli, M., Hoffmann, R.W., Schoel, H. McDowell, T.S., and Hedrick, R.P. (1999). Whirling disease:host specificity and interaction between the actinosporean stage of Myxobolus cerebralis and rainbow trout Oncorhynchus mykiss. Diseases of Aquatic Organisms, 35, 1–12.
- El-Matbouli, M. and Hoffmann, R. (1998). Light and electron microscopic studies on the chronological development of Myxobolus cerebralis to the actinosporean stage in Tubifex tubifex. International Journal for Parasitology, 28, 195–217.
- El-Matbouli, M., Hoffmann, R.W., and Mandok, C. (1995). Light and electron microscopic observations on the route of the triactinomyxon- sporoplasm of Myxobolus cerebralis from epidermis into rainbow trout cartilage. Journal of Fish Biology, 46, 919–935.
