Some 2,5-Disubstitue-1,3,4-Oxadiazoles as New Antioxidants
Abstract
Many heterocyclic compound, a pharmacologically
used as the starting compound for the synthesis of new structures which are
important. Groups of these azole compounds, due to their various biological
activities, in recent years have become common classes of compounds
synthesized. Heterocyclic compounds containing five-membered ring, compounds of
pharmacological class have entered popular in recent years due to properties. In
this study, antioxidant activities of some 2,5-disubstitue-1,3,4-oxadiazoles (1-3) were evaluated for according to ABTS
(2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt), 2,2-diphenyl-1-picrylhydrazyl
(DPPH) radical scavenging activities and iron reducing
power capacity. The obtained results showed that the synthesized
compounds (1-3) had effective
antioxidant activities.
Keywords
2.5-Disubstitue-1.3.4-oxadiazoles,Antioxidant,ABTS Radical Scavenging Activity
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