THE RELATIONSHIP BETWEEN DYSLIPIDEMIA AND THE RISK OF COVID 19 INFECTION

Abstract

OBJECTIVE: The recent coronavirus disease 2019 (COVID-19) outbreak has become a worldwide public health problem. Hypertension, diabetes mellitus, obesity, chronic heart and lung diseases increase the risk of development of COVID-19 infection and severe COVID-19 disease. In this study; we aimed to investigate whether hyperlipidemia alone increases the risk of development of COVID-19 infection.
MATERIAL AND METHODS: One hundred-thirty four patients who were hospitalized with the diagnosis of COVID-19 and did not have any chronic disease and one hundred-twenty-two healthy controls were included in this study. The average of the lipid values of the patient group in the last 6 months before admission was calculated. Likewise, the average of the lipid parameters of the control group in the last 6 months was taken.
RESULTS: There were no differences between two groups with regard to age, gender, and laboratory characteristics. Triglyceride and Low-density lipoprotein cholesterol values were significantly higher and High-density lipoprotein cholesterol levels were significantly lower in the COVID-19 patients compared to the control subjects (p < 0.01).
CONCLUSIONS: Although research on the association of dyslipidemia with COVID-19 is still insufficient, our findings show that serum cholesterol levels are significantly associated with the risk of COVID-19 infection.

Keywords

• Covid-19 Virus
• Dyslipidemia
• Risk factors

DİSLİPİDEMİ VE COVİD 19 ENFEKSİYON RİSKİ ARASINDAKİ İLİŞKİ

Abstract

AMAÇ: Son zamanlarda ortaya çıkan koronavirüs (COVID-19) salgını, küresel bir halk sağlığı sorunu haline gelmiştir. Hipertansiyon, diabetes mellitus, obezite, kronik kalp ve akciğer hastalıkları, COVID-19 enfeksiyonu ve ciddi COVID-19 hastalığı gelişme riskini artırır. Bu çalışmada; hiperlipideminin tek başına COVID-19 enfeksiyonu gelişme riskini artırıp artırmadığını amaçladık.
GEREÇ VE YÖNTEM: Bu çalışmaya COVID-19 tanısı ile hastaneye yatırılan ve herhangi bir kronik hastalığı olmayan 134 hasta ile 122 sağlıklı kontrol alındı. Hasta grubunun başvurudan önceki son 6 aydaki lipid değerlerinin ortalaması hesaplandı. Kontrol grubunun da yine son 6 aylık lipid parametrelerinin ortalaması alındı.
BULGULAR: İki grup arasında yaş, cinsiyet ve laboratuvar özellikleri açısından fark yoktu. COVID-19 hastaları, kontrol deneklerine kıyasla önemli ölçüde daha yüksek trigliserit ve düşük yoğunluklu lipoprotein kolesterol değerlerine ve önemli ölçüde düşük yüksek yoğunluklu lipoprotein kolesterol seviyelerine sahipti (p <0.01).
SONUÇ: Dislipidemi ve COVID-19 ile ilgili mevcut araştırmalar sınırlı olmakla birlikte, bulgularımız serum kolesterol düzeylerinin COVID-19 gelişme riski ile önemli ölçüde ilişkili olduğunu göstermektedir.

Keywords

• Covid-19 Virüs
• Dislipidemi
• Risk faktörleri

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