Abstract
Objective: This study was aimed to investigate the left ventriculer myocardial performance index (Tei index) in patients with coronary slow flow phenomenon Material and Methods: 25 patients with slow coronary flow (15 men; 10 women; mean age 51 ± 12 years) and 20 subjects with angiographically normal coronary arteries (12 men; 8 women; mean age 52 ± 12 years) were included in the study. All the subjects underwent echocardiography and tissue Doppler imaging to determine left ventriculer (LV) diastolic functions and left ventriculer myocardial performance index (LV MPI). Results: Conventional echocardiography parameters, maximal velocity of early diastolic filling (p=0,02), ratio of maximal early to late diastolic filling (p=0,037) were significantly lower, deceleration time of early diastolic filling was significantly higher (p=0,043) in the patient group. Among tissue Doppler parameters the mitral annulus peak early diastolic velocity and ratio of early to late diastolic velocity were lower in patients group than in controls (p
References
- Beltrame JF, Limaye SB, Wuttke RD, et al. Coronary hemodynamic and metabolic studies of the coronary slow phenomenon. Am Heart J 2003;146(1):84-90.
- Hawkins BM, Stavrakis S, Rousan TA, et al. Coronary slow flow prevalence and clinical correlations. Circ J 2012;76(4):936-42.
- Mangieri E, Macchiarelli G, Ciavolella M, et al. Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diagn 1996;37(4):375-81.
- Sezgin AT, Sigirci A, Barutçu I, et al. Vascular endothelial function in patients with slow coronary flow. Coron Artery Dis 2003;14(2):155-61.
- Fineschi M, Bravi A, Gori T. The "slow coronary flow" phenomenon: evidence of preserved coronary flow reserve despite increased resting microvascular resistances. Int J Cardiol 2008;127(3):358-61.
- Ulusoy RE, Yokusoglu M, Baysan O, et al. Ventricular functions, aortic elastic properties, and endothelial functions in patients with hypertensive response to treadmill exercise testing. Turk J Med Sci 2011;41(5):781-7.
- Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93(5):879-88.
- Nurkalem Z, Gorgulu S, Uslu N, et al. Longitudinal left ventricular systolic function is impaired in patients with coronary slow flow. Int J Catdiovasc Imaging 2009;25(1):25-32.
- Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two- Dimensional Echocardiograms. J Am Soc Echocardiogr 1989;2(5):358-67.
- Gaibazzi N, Petrucci N, Ziacchi V. Left ventricle myocardial performance index derived either by conventional method or mitral annulus tissue- doppler: a comparison study in healthy subjects and subjects with heart failure. J Am Soc Echocardiogr 2005;18(12):1270-6.
- Kang SM, Ha JW, Rim SJ, et al. Index of myocardial performance using doppler-derived parameters in the evaluation of left ventricular function in patients with essential hypertension. Yonsei Med J 1998;39(5):446
- Baykan M, Baykan EC, Turan S, et al. Assessment of left ventricular function and Tei index by tissue doppler imaging in patients with slow coronary flow. Echocardiography 2009;26(10):1167-72.
- Elsherbiny IA. Left ventricular function and exercise capacity in patients with slow coronary flow. Echocardiography 2012;29(2):158-64.
- Cin VG, Pekdemir H, Camsar A, et al. Diffuse intimal thickening of coronary arteries in slow coronary flow. Jpn Heart J 2003;44(6):907-19.
- Fineschi M, Bravi A, Gori T. The "slow coronary flow" phenomenon: evidence of preserved coronary flow reserve despite increased resting microvascular resistances. Int J Cardiol 2008;127(3):358-61.
- Kopetz VA, Penno MA, Hoffmann P, et al. Potential mechanisms of the acute coronary syndrome presantation in patients with the coronary slow flow phenomenon-insight from a plasma proteomic approach. Int J Cardiol 2012;156(1):84-91.
- Yalcin F, Thomas J. Diastolic dysfunction: pathogenesis, therapy and the importance of doppler echocardiography. Turk J Med Sci 1999;29(1):501-6.
Abstract
Amaç: Bu çalışmada koroner yavaş akımı olan hastalarda sol ventrikül miyokard performans indeksinin (Tei indeksi) incelenmesi amaçlanmıştır. Gereç ve Yöntem: Koroner yavaş akımı olan 25 hasta (15 erkek; 10 kadın; ort yaş 51 ± 12 yıl) ve koroner arterleri normal olan 20 olgu (12 erkek; 8 kadın; ort yaş 52 ± 12 yıl) çalışmaya alınmıştır. Tüm hastaların ekokardiyografi ve doku doppler görüntüleme ile sol ventrikül diyastolik fonksiyonları ve miyokard performans indeksi saptandı. Bulgular: Koroner yavaş akımı olan grupta maksimal erken diyastolik dolum hızı, maksimal erken diyastolik dolum hızının geç diyastolik akım hızına oranı (p=0,037) anlamlı derecede düşük saptanırken; erken diyastolik dolum hızı deselerasyon zamanı anlamlı derecede yüksekdi (p=0,043). Hasta grubunda, kontrol grubuna göre doku doppler parametreleri arasında mitral anulus erken pik diyastolik hız ve erken diyastolik akım oranı anlamlı derecede düşük saptandı (p<0.001) ancak izovolümetrik relaksasyon zamanı anlamlı derecede artmış olarak bulundu (p<0.001). Sol ventrikül miyokard performans indeksi koroner yavaş akımı olan grupta anlamlı derecede uzamıştır( p < 0.001). TIMI kare sayısı ile mitral lateral anulus erken diyastolik hız ve mitral lateral anulus erken diyastolik hızın geç diyastolik hıza oranı arasında negatif korelasyon saptanırken, izovolümetrik relaksasyon zamanı ve sol ventrikül miyokard performans indeksi ile pozitif korelasyon saptanmıştır. Sonuç: Çalışmamızda koroner yavaş akımlı hastalarda diyastolik fonksiyonların ve miyokard performans indeksinin etkilendiğini gösterdik. Bu nedenle koroner yavaş akımı olan hastalar dikkatli bir şekilde takip edilmelidir
References
- Beltrame JF, Limaye SB, Wuttke RD, et al. Coronary hemodynamic and metabolic studies of the coronary slow phenomenon. Am Heart J 2003;146(1):84-90.
- Hawkins BM, Stavrakis S, Rousan TA, et al. Coronary slow flow prevalence and clinical correlations. Circ J 2012;76(4):936-42.
- Mangieri E, Macchiarelli G, Ciavolella M, et al. Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diagn 1996;37(4):375-81.
- Sezgin AT, Sigirci A, Barutçu I, et al. Vascular endothelial function in patients with slow coronary flow. Coron Artery Dis 2003;14(2):155-61.
- Fineschi M, Bravi A, Gori T. The "slow coronary flow" phenomenon: evidence of preserved coronary flow reserve despite increased resting microvascular resistances. Int J Cardiol 2008;127(3):358-61.
- Ulusoy RE, Yokusoglu M, Baysan O, et al. Ventricular functions, aortic elastic properties, and endothelial functions in patients with hypertensive response to treadmill exercise testing. Turk J Med Sci 2011;41(5):781-7.
- Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93(5):879-88.
- Nurkalem Z, Gorgulu S, Uslu N, et al. Longitudinal left ventricular systolic function is impaired in patients with coronary slow flow. Int J Catdiovasc Imaging 2009;25(1):25-32.
- Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two- Dimensional Echocardiograms. J Am Soc Echocardiogr 1989;2(5):358-67.
- Gaibazzi N, Petrucci N, Ziacchi V. Left ventricle myocardial performance index derived either by conventional method or mitral annulus tissue- doppler: a comparison study in healthy subjects and subjects with heart failure. J Am Soc Echocardiogr 2005;18(12):1270-6.
- Kang SM, Ha JW, Rim SJ, et al. Index of myocardial performance using doppler-derived parameters in the evaluation of left ventricular function in patients with essential hypertension. Yonsei Med J 1998;39(5):446
- Baykan M, Baykan EC, Turan S, et al. Assessment of left ventricular function and Tei index by tissue doppler imaging in patients with slow coronary flow. Echocardiography 2009;26(10):1167-72.
- Elsherbiny IA. Left ventricular function and exercise capacity in patients with slow coronary flow. Echocardiography 2012;29(2):158-64.
- Cin VG, Pekdemir H, Camsar A, et al. Diffuse intimal thickening of coronary arteries in slow coronary flow. Jpn Heart J 2003;44(6):907-19.
- Fineschi M, Bravi A, Gori T. The "slow coronary flow" phenomenon: evidence of preserved coronary flow reserve despite increased resting microvascular resistances. Int J Cardiol 2008;127(3):358-61.
- Kopetz VA, Penno MA, Hoffmann P, et al. Potential mechanisms of the acute coronary syndrome presantation in patients with the coronary slow flow phenomenon-insight from a plasma proteomic approach. Int J Cardiol 2012;156(1):84-91.
- Yalcin F, Thomas J. Diastolic dysfunction: pathogenesis, therapy and the importance of doppler echocardiography. Turk J Med Sci 1999;29(1):501-6.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | August 1, 2014 |
| Published in Issue | Year 2014 Volume: 15 Issue: 2 |
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