20-25 Yaş Arası Sağlıklı Gençlerde Gri ve Beyaz Cevher Hacimlerinin İncelenmesi: Planimetrik Çalışma

Year 2008, Volume: 9 Issue: 2, 45 - 51, 01.08.2008

Niyazi Acer - Tolga Ertekin - Ayşegül Kü Çamurdanoğlu Niyazi Acer Tolga Ertekin Ayşegül Küçük Cumhur Babaoğlu , M. Niyazi Çankaya Mehmet Çamurdanoğlu

Abstract

Keywords

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20-25 Yaş Arası Sağlıklı Gençlerde Gri ve Beyaz Cevher Hacimlerinin İncelenmesi: Planimetrik Çalışma

Abstract

Amaç: İnsan beyninde cinsiyete ilişkin varyasyonlar birçok araştırıcı tarafından incelenmiştir. Bu çalışmaların çoğunda erkek beyin hacminin bayanlardan daha büyük olduğu bildirilmektedir. Bu çalışmanın amacı MR görüntüleri üzerinde beyaz ve gri cevher ölçümleri planimterik yöntem ile değerlendirmektir. Gereç ve Yöntemler: Bu çalışmada beyaz ve gri cevher hacimleri 20-25 yaş arası sağlıklı gençlerde incelenmiştir. T2 ağırlıklı MR görüntüleri 12 kişi üzerinde elde edilmiş, kadın ve erkeklerde beyaz (BC) ve gri cevher (GC) oranını belirlemek için planimetrik ölçüm yapılmıştır. Total beyin hacmi (TBH), beyaz ve gri cevher hacimleri yarı otomatik yazılımla bilgisayar üzerinden yapılmıştır. Total beyin hacmi, beyaz ve gri cevher hacim ölçüm sonuçları cinsiyetler arasında bağımsız t testi ile karşılaştırılmıştır. Tahmin edilen hacimlerin istatistiksel analizi sağ ve sol taraf için unpaired t testi ile yapılmıştır. Bulgular: Cinsiyet ve taraflar (sağ ve sol) arasında istatistiksel olarak anlamlı fark olmadığı bulundu. Ancak beyaz cevherler açısından α = 0.1 alındığında fark olduğu ve kadınlara göre erkeklerde beyaz cevherin hacminin daha büyük olduğu istatistiksel olarak kanıtlandı. P-değerinin 0.085 olmasından dolayı cinsiyetlere göre sol beyaz cevherde fark olmadığını göstermektedir. Sonuç: Gri ve beyaz cevherin oranları beyin atrofisini anlamada bize yardımcı olabilir. Aynı zamanda beyaz ve gri cevherin hacim hesabı için bu metot güvenilir ve geçerlidir

Keywords

manyetik rezonans görüntüleme, beyin, anatomi

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