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PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER

Year 2017, Volume: 18 Issue: 4, 130 - 135, 16.10.2017
https://doi.org/10.18229/kocatepetip.368668

Abstract

AMAÇ: Kronik Böbrek Hastalığı (KBH) insidansı ve prevalansı
tüm dünyada artmaktadır. KBH’da sıklıkla komplikasyonlar
fazladır ve kötü yaşam kalitesi ile birliktedir. Bu
çalışmanın amacı Kısa form-36 (SF-36) ölçeği ile KBH’da
yaşam kalitesinin değerlendirilmesi ve böbrek fonksiyonları,
yaş, cinsiyet, eğitim düzeyi, sosyo ekonomik durum,
hemoglobin, albumin, HBA1c, 25OHvitamin D düzeyinin
yaşam kalitesi üzerindeki etkisinin araştırılmasıdır.
GEREÇ VE YÖNTEM: Bu kesitsel çalışma Antalya Eğitim
ve Araştırma Hastanesinde takipli 211 KBH tanılı hastada
(ortalama yaş 56 ± 13 yıl), Ocak-Haziran 2016 tarihleri
arasında yapıldı. Hastaların yaşam kalitesini saptamak
için SF-36 ölçeği kullanıldı ve laboratuvar testleri, klinik
ve demografik verileri kayıt edildi.
BULGULAR: KBH-EPI formülü kullanılarak hastalar KBH
evrelerine ayrıldı. Hastaların %59,2’si Evre 1-3, %40,8’i
Evre 4-5 olarak saptandı. Evre 4-5 hastalarda fiziksel rol
güçlüğü skoru daha düşük saptandı. Yaşın yaşam kalitesini
negatif etkilediği görüldü. Hemoglobin, albumin ve 25
OH vitamin D düzeylerindeki artışın fiziksel fonksiyon ve
fiziksel rol güçlüğü skorlarında artışla birlikte olduğu saptandı.
Artmış HbA1C düzeylerinin kötü fiziksel fonksiyon
skoruyla ilişkili olduğu görüldü. Eğitim düzeyi ,sosyo ekonomik
durum ile yaşam kalitesi arasında ilişki saptandı.
SONUÇ: KBH tanılı hastada böbrek fonksiyonları, yaş, cinsiyet,
eğitim düzeyi ve sosyoekonomik durum yaşam kalitesini
etkilemektedir. KBH’da yaşam kalitesini artırmak
için; hemoglobin, albumin, HbA1c ve 25 OH vitamin D
düzeyleri gibi değiştirebileceğimiz faktörleri iyileştirmeliyiz.

References

  • Andrew S. Levey, Josef Coresh, National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39(2-1):S1–266.
  • Süleymanlar G, Utaş C, Arinsoy T ,et al.A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study. Nephrol Dial Transplant. 2011 Jun;26(6):1862-71.
  • Perlman RL, Finkelstein FO, Liu L, et al. Quality of life in chronic kidney disease (CKD): a cross-sectional analysis in the Renal Research Institute CKD study. Am J Kidney Dis. 2005;45:658–66.
  • Harris LE, Luft FC, Rudy DW, Tierney WM. Clinical correlates of functional status in patients with chronic renal insufficiency. AmJ Kidney Dis. 1993;21:161–6.
  • Sesso R, Yoshihiro MM. Time of diagnosis of chronic renal failure and assessment of quality of life in hemodialysis patients. Nephrol Dial Transplant. 1997;12:2111–16.
  • Koçyiğit H, Aydemir Ö, Fişek G, Ölmez N, Memiş A: Kısa form- 36 (KF-36)’nın türkçe versiyonunun güvenilirliği. İlaç ve Tedavi Dergisi 1999;12:102-106
  • Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009;150:604-12.
  • Ware JE, Jr., Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473–83.
  • Conde´ SA, Fernandes N, Santos FR, Chouab A, Mota MM, Bastos MG. Cognitive decline, depression and quality of life in patients at different stages of chronic kidney disease. J Bras Nefrol. 2010;32:242–8.
  • Boini S, Frimat L, Kessler M, Briançon S, Thilly N. Predialysis therapeutic care and health-related quality of life at dialysis onset (The pharmacoepidemiologic AVENIR study). Health Qual Life Outcomes. 2011;9:7.
  • Kusek JW, Greene P, Wang S-R, et al. Crosssectional study of health-related quality of life in african americanswith chronic renal insufficiency: the african american study of kidney disease and hypertension trial. Am J Kidney Dis. 2002;39(3):513–24.
  • Chow FY, Briganti EM, Kerr PG, et al. Health-related quality of life in australian adults with renal insufficiency: a populationbased study. Am J Kidney Dis. 2003;41(3):596–604.
  • Cruz MC, Andrade C, Urrutia M, Draibe S, Nogueira-Martins LA, de Castro Cintra Sesso R. Quality of life in patients with chronic kidney disease. Clinics. 2011;66(6):991–5.
  • Alexander M, Kewalramani R, Agodoa I, Globe D. Association of anemia correction with health related quality of life in patients not on dialysis. Curr Med Res Opin. 2007;23(12):2997–3008.
  • Akizawa T, Gejyo F, Nishi S, et al. Positive outcomes of high hemoglobin target in patients with chronic kidney disease not on dialysis: a randomized controlled study. Ther Apher Dial. 2011;15(5):431–40.
  • Mittal SK, Aherm L, Flaster E, Maesaka JK and Fishbane S. Selfassessed physical and mental functional of hemodialysis patients. Nephrol Dial Transplant. 2001;16:1387 94.
  • Migardi G, The DIA-QOL Group: From the development to the clinical application of a questionnaire on the quality of life in dialysis. The experience of the Italian Collaborative DIA-QOL (Dialysis-Quality of Life) Group. Nephrol Dial Transplant,1998; 13: 70-75.
  • Chao YS1, Ekwaru JP, Ohinmaa A, Griener G, Veugelers PJ. Vitamin D and health-related quality of life in a community sample of older Canadians. Qual Life Res. 2014 Nov;23(9):2569- 75.
  • Tavallaii SA1, Einollahi B, Azizabadi Farahani M, Namdari M.Socioeconomic links to health-related quality of life, anxiety, and depression in kidney transplant recipients.Iran J Kidney Dis. 2009 Jan;3(1):40-4.
  • Lew SQ, Patel SS. Psychosocial and quality of life issues in women with end-stage renal disease. Adv Chronic Kidney Dis. 2007;14(4):358–63.

A CROSS-SECTIONAL STUDY IN PATIENTS WITH PRE-DIALYSIS CHRONIC KIDNEY DISEASE: QUALITY OF LIFE AND RELATED FACTORS

Year 2017, Volume: 18 Issue: 4, 130 - 135, 16.10.2017
https://doi.org/10.18229/kocatepetip.368668

Abstract

OBJECTIVE: The incidence and prevalence of patients
with chronic kidney disease (CKD) is increasing worldwide.
It is often associated with a high prevalence of complications
and worse quality of life. The main objective of
this study is to evaluate quality of life (QOL) using the
generic instrument short form-36 (SF-36) in patients with
CKD and identify the possible influence of the degree of
renal function, age, gender, education level, socioeconomic
status, hemoglobin, albumin, HbA1c and 25 hydroxy
vitamin D level on QOL.

MATERIALS AND METHODS: For this cross-sectional
study, we included 211 CKD patients ( median age 56 ±
13 years) admitted to the outpatient clinic of Antalya Research
and Training Hospital Nephrology Unit between
January and June 2016. Participants completed the short
form-36 health survey (SF-36). Laboratory tests and clinical
and demographic data were obtained.

RESULTS: The patients were classified into CKD stages
according to the CKD-EPI equation: 59,2% were in CKD
Stage 1-3 and 40,8% were in Stage 4-5. The patients in
Stage 4-5 had lower scores in physical aspects. Age influence
QOL negatively. CKD patients with higher hemoglobin,
albumin and 25 hydroxy vitamin D levels has better
functional capacity and physical aspects. High HbA1c levels
significantly associated with bad functional capacity.
Education level and socioeconomic status is associated
with QOL.

CONCLUSIONS: Renal function, age, gender, education
level and socioeconomic status influenced QOL. To imrove
QOL in CKD patients we need to focus on factors that
can be changed, such as improving the hemoglobin, albumin,
HbA1c and 25 hydroxy vitamin D levels. 

References

  • Andrew S. Levey, Josef Coresh, National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39(2-1):S1–266.
  • Süleymanlar G, Utaş C, Arinsoy T ,et al.A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study. Nephrol Dial Transplant. 2011 Jun;26(6):1862-71.
  • Perlman RL, Finkelstein FO, Liu L, et al. Quality of life in chronic kidney disease (CKD): a cross-sectional analysis in the Renal Research Institute CKD study. Am J Kidney Dis. 2005;45:658–66.
  • Harris LE, Luft FC, Rudy DW, Tierney WM. Clinical correlates of functional status in patients with chronic renal insufficiency. AmJ Kidney Dis. 1993;21:161–6.
  • Sesso R, Yoshihiro MM. Time of diagnosis of chronic renal failure and assessment of quality of life in hemodialysis patients. Nephrol Dial Transplant. 1997;12:2111–16.
  • Koçyiğit H, Aydemir Ö, Fişek G, Ölmez N, Memiş A: Kısa form- 36 (KF-36)’nın türkçe versiyonunun güvenilirliği. İlaç ve Tedavi Dergisi 1999;12:102-106
  • Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009;150:604-12.
  • Ware JE, Jr., Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473–83.
  • Conde´ SA, Fernandes N, Santos FR, Chouab A, Mota MM, Bastos MG. Cognitive decline, depression and quality of life in patients at different stages of chronic kidney disease. J Bras Nefrol. 2010;32:242–8.
  • Boini S, Frimat L, Kessler M, Briançon S, Thilly N. Predialysis therapeutic care and health-related quality of life at dialysis onset (The pharmacoepidemiologic AVENIR study). Health Qual Life Outcomes. 2011;9:7.
  • Kusek JW, Greene P, Wang S-R, et al. Crosssectional study of health-related quality of life in african americanswith chronic renal insufficiency: the african american study of kidney disease and hypertension trial. Am J Kidney Dis. 2002;39(3):513–24.
  • Chow FY, Briganti EM, Kerr PG, et al. Health-related quality of life in australian adults with renal insufficiency: a populationbased study. Am J Kidney Dis. 2003;41(3):596–604.
  • Cruz MC, Andrade C, Urrutia M, Draibe S, Nogueira-Martins LA, de Castro Cintra Sesso R. Quality of life in patients with chronic kidney disease. Clinics. 2011;66(6):991–5.
  • Alexander M, Kewalramani R, Agodoa I, Globe D. Association of anemia correction with health related quality of life in patients not on dialysis. Curr Med Res Opin. 2007;23(12):2997–3008.
  • Akizawa T, Gejyo F, Nishi S, et al. Positive outcomes of high hemoglobin target in patients with chronic kidney disease not on dialysis: a randomized controlled study. Ther Apher Dial. 2011;15(5):431–40.
  • Mittal SK, Aherm L, Flaster E, Maesaka JK and Fishbane S. Selfassessed physical and mental functional of hemodialysis patients. Nephrol Dial Transplant. 2001;16:1387 94.
  • Migardi G, The DIA-QOL Group: From the development to the clinical application of a questionnaire on the quality of life in dialysis. The experience of the Italian Collaborative DIA-QOL (Dialysis-Quality of Life) Group. Nephrol Dial Transplant,1998; 13: 70-75.
  • Chao YS1, Ekwaru JP, Ohinmaa A, Griener G, Veugelers PJ. Vitamin D and health-related quality of life in a community sample of older Canadians. Qual Life Res. 2014 Nov;23(9):2569- 75.
  • Tavallaii SA1, Einollahi B, Azizabadi Farahani M, Namdari M.Socioeconomic links to health-related quality of life, anxiety, and depression in kidney transplant recipients.Iran J Kidney Dis. 2009 Jan;3(1):40-4.
  • Lew SQ, Patel SS. Psychosocial and quality of life issues in women with end-stage renal disease. Adv Chronic Kidney Dis. 2007;14(4):358–63.
There are 20 citations in total.

Details

Subjects Health Care Administration
Journal Section Articles
Authors

Ayça İnci

Melahat Çoban This is me

Metin Sarıkaya This is me

Ümmühan Maden This is me

Publication Date October 16, 2017
Acceptance Date May 3, 2017
Published in Issue Year 2017 Volume: 18 Issue: 4

Cite

APA İnci, A., Çoban, M., Sarıkaya, M., Maden, Ü. (2017). PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER. Kocatepe Tıp Dergisi, 18(4), 130-135. https://doi.org/10.18229/kocatepetip.368668
AMA İnci A, Çoban M, Sarıkaya M, Maden Ü. PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER. KTD. October 2017;18(4):130-135. doi:10.18229/kocatepetip.368668
Chicago İnci, Ayça, Melahat Çoban, Metin Sarıkaya, and Ümmühan Maden. “PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER”. Kocatepe Tıp Dergisi 18, no. 4 (October 2017): 130-35. https://doi.org/10.18229/kocatepetip.368668.
EndNote İnci A, Çoban M, Sarıkaya M, Maden Ü (October 1, 2017) PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER. Kocatepe Tıp Dergisi 18 4 130–135.
IEEE A. İnci, M. Çoban, M. Sarıkaya, and Ü. Maden, “PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER”, KTD, vol. 18, no. 4, pp. 130–135, 2017, doi: 10.18229/kocatepetip.368668.
ISNAD İnci, Ayça et al. “PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER”. Kocatepe Tıp Dergisi 18/4 (October 2017), 130-135. https://doi.org/10.18229/kocatepetip.368668.
JAMA İnci A, Çoban M, Sarıkaya M, Maden Ü. PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER. KTD. 2017;18:130–135.
MLA İnci, Ayça et al. “PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER”. Kocatepe Tıp Dergisi, vol. 18, no. 4, 2017, pp. 130-5, doi:10.18229/kocatepetip.368668.
Vancouver İnci A, Çoban M, Sarıkaya M, Maden Ü. PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER. KTD. 2017;18(4):130-5.

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