ASSESSMENT OF BLOOD CULTURE AND BLOOD PARAMETERS IN PEDIATRIC PATIENTS DIAGNOSED WITH PNEUMONIA

Year 2022, Volume: 23 Issue: 2, 196 - 201, 20.04.2022

Raziye Dut , Ahmet Taşkın

https://doi.org/10.18229/kocatepetip.815285

Abstract

OBJECTIVE: It is recommended to take a blood culture test in pediatric patients diagnosed with pneumonia. However, the rate of pathogenic microorganisms produced in blood culture tests is quite low. In this study, the results of blood culture tests and some blood test parameters in pediatric patients hospitalized with pneumonia diagnosis were evaluated.
MATERIAL AND METHODS: 643 patients who were hospitalized and diagnosed with pneumonia in accordance with ICD10 coding and whose blood culture test was taken between 2016 and 2018 were included in the study. The results of blood culture tests and blood test parameters ((WBC (White Blood Count), ANC (Absolute Neutrophil Count), AMC (Absolute Monosite Count), MPV (Mean Platelet Volume), PDW (Platelet Distribution Wide), PCT (Plateletcrit)) and CRP (C-Reaktif Protein)) were evaluated.
RESULTS: The mean age of the patients was 27.1±38.2 months and 41.8% of the patients were female. Blood culture results were positive in 4.0% of the patients (n=26). The platelet count of the patients with positive blood culture (307.3/ml) was lower than those with negative blood culture (360.2/ml) (p=0.035) but no differences were found in the CRP levels (p = 0.095), total white blood cell count (p = 0.069) and MPV (p= 0.846) values. PDW level was found higher (p <0.001) in patients with positive blood culture (12.7±2.6%) than those with negative blood culture (10.4±1.7%). The most frequently isolated pathogen was Staphylococcus Hominis (n=8, 36.4%).
CONCLUSIONS: The rate of detection of pathogenic microorganisms in the blood culture test in pediatric patients hospitalized with the diagnosis of pneumonia is at a very low level. In these patients, the demonstration of pathogen bacteria in the blood culture test is valuable for the treatment of the disease and choice of empirical antibiotherapy. It is necessary to conduct studies on the use of other blood parameters in the diagnosis, treatment and clinical follow-up of pneumonia in children.

Keywords

Pneumonia, Culture, Pathogen, Blood test, Children.

PNÖMONİ TANISI ALAN ÇOCUK HASTALARDA KAN KÜLTÜRÜ VE KAN PARAMETRELERİNİN DEĞERLENDİRİLMESİ

Abstract

AMAÇ: Pnömoni tanısı alan çocuk hastalarda kan kültürü testi alınması önerilmektedir. Ancak, kan kültürü testlerinde üretilen patojen mikroorganizma oranı oldukça düşüktür. Bu çalışmada; pnömoni tanısı ile hastaneye yatırılan çocuk hastalarda kan kültürü sonuçları ve bazı kan testi parametreleri araştırıldı.
GEREÇ VE YÖNTEM: 2016 - 2018 tarihleri arasında ICD10 kodlamasına uygun olarak pnömoni tanısı ile hastaneye yatırılan ve kan kültürü testi alınan 643 hasta çalışmaya dahil edildi. Kan kültür sonuçları, kan testi parametreleri (WBC (White Blood Count), ANC (Absolute Neutrophil Count), AMC (Absolute Monosite Count), trombosit sayısı, MPV (Mean Platelet Volume), PDW (Platelet Distribution Wide), PCT (Plateletcrit)) ve CRP (C-Reaktif Protein) değerlendirildi.
BULGULAR: Ortalama yaş 27.1±38.2ay, %41,8’i kız cinsiyet idi. %4,0 oranında (n=26) kan kültürü sonucu pozitifti. Kan kültürü pozitif olan hastaların trombosit sayısı (307.3/mL) kan kültürü negatif olanlardan (360.2/mL) daha düşüktü (p=0.035), ancak; CRP (p=0.095), toplam beyaz küre sayısı (p=0.069) ve MPV (p=0.846) sonuçları ile fark bulunamadı. Kan kültür sonucu pozitif olanlarda PDW (%12,7±2,6) negatif olanlardan (%10,4±1.7) daha yüksek bulundu (p<0.001). En sık izole edilen patojen Stafilokok Hominis (n=8, %36,4) idi.
SONUÇ: Pnömoni tanısı ile hastaneye yatırılan çocuk hastalarda kan kültürü testinde patojen mikroorganizmanın gösterilme oranı oldukça düşük seviyededir. Bu hastalarda; kan kültürü testinde patojen bakterinin gösterilmesi hastalığın tedavisi ve ampirik antibiyoterapi seçimi için kıymetlidir. Çocuklarda pnömoni tanı, tedavi ve klinik izleminde diğer kan parametrelerinin kullanımı konusunda çalışmalara ihtiyaç vardır.

Keywords

Pnömoni, Kültür, Patojen, Kan testi, Pediatri

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