PREEKLAMPSİ TANISINDA SPOT İDRAR PROTEİN / KREATİNİN ORANININ SENSİTİVİTESİNİN İDRAR VERME ZAMANI VE BEKLEME SÜRESİ GİBİ DEĞİŞKENLER İLE BİRLİKTE BELİRLENMESİ

Year 2022, Volume: 23 Issue: 4, 364 - 371, 17.10.2022

Kemal Hansu , Halis Özdemir , Merih Bayram

https://doi.org/10.18229/kocatepetip.980888

Abstract

AMAÇ: Bu çalışmada 24 saatlik idrar proteinürisini öngörmede spot idrar protein / kreatinin oranının başarısını, idrarın verilme zamanı ve idrarın bekleme süresi gibi farklı değişkenler ile karşılaştırmayı amaçladık.
GEREÇ VE YÖNTEM: Çalışmaya Mart 2014 - Aralık 2017 tarihleri arasında tansiyon yüksekliği nedeniyle kliniğimize başvuran, 24 saatlik idrarda protein çalışılan ve eş zamanlı spot idrarda protein/kreatinin oranı bakılan 100 gebe dahil edilmiştir. Çalışmaya katılan gebeler 24 saatlik idrar proteinürisi normal sınırlarda olanlar ve olmayanlar olarak ikiyi ayrılmıştır. Spot idrarın veriliş zamanı, bekleme süresi ve hastaların demografik verileriyle; spot idrar kreatinin oranın 24 saatlik idrar proteinürisini öngörmedeki başarısı karşılaştırılmıştır.
BULGULAR: Spot idrar protein / kreatinin oranının 24 saatlik idrarda proteinürisi olan ve olmayan gruplara ait en iyi kestirim noktası 0.315 olarak belirlenmiştir. İdrar verilme zamanı ve idrar bekleme süreleri karşılaştırılmış ancak istatistiksel olarak anlamlı bir fark olmadığı görülmüştür.
SONUÇ: Preeklampsi şüphesi olan gebelerde spot idrar protein/kreatinin oranı bakılması, 24 saatlik idrarda proteinüri bakılmasının yerini alabilir ancak çalışmamıza göre idrar verilme zamanı ve analiz öncesi idrar bekleme süresi testin duyarlılığını etkilememiştir.

Keywords

Pre-eklampsi, Gebelik toksemileri, Proteinüri

Supporting Institution

yoktur

DETERMINING SPOT URINE PROTEIN / CREATININE RATIO SENSITIVITY IN THE DIAGNOSIS OF PREECLAMPSIA WITH VARIABLES SUCH AS URINE SAMPLING TIME AND WAITING TIME

Abstract

OBJECTIVE: The present study aims to compare the success of spot urine protein/creatinine ratio in predicting 24-h proteinuria with different variables such as urine sampling time and urine wait time before analysis.
MATERIAL AND METHODS: The study included 100 pregnant women who were tested for their 24-h urine protein levels and simultaneously checked for spot urine protein/creatinine ratio upon admission to our clinic with a complaint of high blood pressure between March 2014 and December 2017. The pregnant women included in the study were divided into two groups: those with a normal range for the level of 24-h proteinuria and those with an abnormal range for 24-h proteinuria. The success of spot urine protein/creatinine level in predicting 24-h urine proteinuria was assessed in relation to spot urine sampling time, wait time, and patients’ demographic data.
RESULTS: The optimal cut-off value of spot urine protein / creatinine ratio for groups with and without proteinuria in 24-h urine was determined to be 0.315 (cut-off). Urine sampling time and wait time before analysis were compared but no statistically significant difference was found.
CONCLUSIONS: The spot urine protein/creatinine ratio in pregnant women with suspected preeclampsia may replace testing patients for proteinuria in their 24-h urine. However, according to our study, urine sampling time and wait time before analysis did not affect the sensitivity of the test.

Keywords

Preeclampsia, Toxemia Of Pregnancy, Proteinuria

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