Evaluation to Treatment Adherence, Rational Drug Use in Hemodialysis Patients and Predictive Factors on Dialysis Adequacy

Jale Akgöl; Elif Dizen Kazan; Sinan Kazan; Onur Tunca

doi:10.17517/ksutfd.1176552

TR EN

Hemodializ Hastalarında Tedavi Uyumu, Akılcı İlaç Kullanımının Değerlendirilmesi ve Diyaliz Yeterliliğini Öngörücü Faktörler

Öz

Amaç: Bu çalışmada hemodiyaliz hastalarında tedaviye uyum ve akılcı ilaç kullanımının değerlendirilmesi ve diyaliz yeterliliğini öngören faktörlerin araştırılması amaçlanmıştır. Gereç ve Yöntemler: Bu, kesitsel tanımlayıcı bir çalışmadır. Veriler yüz yüze anketler ve hasta dosyaları incelenerek elde edildi. Hastalara Hastanede Yatan Hasta Anketi ve Son Dönem Böbrek Hastalığı Uyum Anketi (ESRD-AQ) uygulandı. Diyaliz yeterliliği için Kt/V değeri kullanıldı. Elde edilen veriler incelenerek Kt/V değeri ile ilişkilendirilebilecek değişkenler araştırılmıştır. Bulgular: Çalışmaya toplam 145 hasta dahil edildi. Katılımcıların %69’u 51 yaş üstü ve %54.5’i erkekti. Medyan Kt/v değeri 1.38 idi (Q1=1.25; Q3=1.54). İlaçlara gelince, Kt∕V≥1.2 olanların Kt/V<1.2 olan gruba göre daha fazla antihipertansif ajan, folik asit, vitamin B12 ve vitamin C kullandığı ancak daha az levokarnitin kullandığı bulundu (p<0.05). Son Dönem Böbrek Yetmezliği Uyum Anketindeki Medyan Puanı 1150 idi (Q1=1050; Q3=1200). Toplam Uyum Skoru Kt/V≥1.2 olan grupta istatistiksel olarak anlamlı derecede yüksek bulundu (p<0.05). Sonuç: Araştırmaya katılan hastaların tedaviye uyum düzeylerinin oldukça yüksek olduğu belirlendi. Toplam uyum puanları arttıkça yeterli diyaliz alma olasılığı artmaktaydı. Hastaların akılcı ilaç kullanımına ilişkin bilgi düzeyi uyumu etkiler. Bu çalışmada folik asit, C vitamini ve levokarnitin kullanımı diyaliz yeterliliği ile ilişkilendirilmiştir.

Anahtar Kelimeler

Akılcı İlaç Kullanımları , Diyaliz yeterliliği , ESRD-AQ , Hemodiyaliz , Uyum

Evaluation to Treatment Adherence, Rational Drug Use in Hemodialysis Patients and Predictive Factors on Dialysis Adequacy

Abstract

Objective: This study aimed to evaluate treatment adherence and rational drug use in hemodialysis patients and investigate predictive factors on dialysis adequacy. Materıals and Methods: This is a cross-sectional descriptive study. The data were obtained by examining face-to-face questionnaires and patient files. The Hospitalized Patient Questionnaire and the End Stage Kidney Disease Compliance Questionnaire (ESRD-AQ) were administered to the patients. Kt/V was used for dialysis proficiency. By examining the obtained data, the variables that can be associated with the Kt/V value were investigated. Results: A total of 145 patients were included in the study. Sixty nine percent of the participants were over 51 years of age and 54.5% were male. Median Kt/V level was 1.38 (Q1=1.25; Q3=1.54). As for the medications, those with Kt∕V≥1.2 were found to be using more antihypertensive agents, folic acid, vitamin B12, and vitamin C but less levocarnitine concerning the group with Kt/V<1.2 (p<0.05). The Median Score on the End-Stage Renal Failure Adherence Questionnaire was 1150 (Q1=1050; Q3=1200). Total Adherence Score was found to be statistically significantly higher in the group with Kt/V≥1.2 (p<0.05). Conclusıon: It was determined that the level of treatment adherence of the patients participating in the study were considerably high. The probability of receiving adequate dialysis increased as total adherence scores increased. The knowledge level of patients on rational drug use affects adherence. In this study, folic acid, vitamin C, and levocarnitine were associated with dialysis adequacy.

Keywords

Adherence , Rational Drug Uses , Dialysis adequacy , ESRD-AQ , Hemodialysis

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Jale Akgöl ^*
0000-0002-9163-3991
Türkiye

Elif Dizen Kazan
0000-0003-3550-0964
Türkiye

Sinan Kazan
0000-0001-7290-4680
Türkiye

Onur Tunca
0000-0003-1958-7617
Türkiye

Publication Date

March 16, 2023

Submission Date

September 17, 2022

Acceptance Date

October 3, 2022

Published in Issue

Year 2023 Volume: 18 Number: 1

DOI

https://doi.org/10.17517/ksutfd.1176552

IZ

https://izlik.org/JA58JW29YJ

AMA

1.Akgöl J, Dizen Kazan E, Kazan S, Tunca O. Evaluation to Treatment Adherence, Rational Drug Use in Hemodialysis Patients and Predictive Factors on Dialysis Adequacy. KSU Medical Journal. 2023;18(1):153-162. doi:10.17517/ksutfd.1176552

Cited By

Structural Equation Modeling of Treatment Adherence Based on General Health and Demographic Characteristics in Patients Undergoing Hemodialysis

Nephro-Urology Monthly

https://doi.org/10.5812/numonthly-140108