Research Article

Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis

Volume: 15 Number: 2 July 8, 2020
Ayhan Atıgan *, Ömer Tolga Güler
PDF Download
KSU Medical Journal Cover KSU Medical Journal
EN TR

Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis

Abstract

Objective: Endometriosis is characterized by the development of endometrial tissue outside the uterine cavity. Aim of this study is to investigate the diagnostic value of neutrophil/lymphocyte ratio (NLR)  and cancer antigen (CA)-125 in a diagnosis of endometriosis.

Material and methods: In this retrospective study, the medical data of a total of  30 patients who underwent surgery due to endometriosis between January 2012 to December 2017 at Pamukkale University were analyzed.

Results: NLR and CA-125 were increased in the patients with endometriosis.

Conclusion: A diagnostic test without the need for surgery will reduce the associated surgical risks, increase accessibility to a diagnostic test and improve treatment outcomes.

Keywords

Endometriosis,neutrophil/lymphocyte ratio,tumor markers

References

  1. 1. Giudice LC, Kao LC. Endometriosis. Lancet 2004;364:1789-99.
  2. 2. Giudice LC, Clinical practice Endometriosis. N. Engl. J. Med. 2010;362:2389–98.
  3. 3. Mounsey AL, Wilgus A, Slawson DC. Diagnosis and management of endometriosis. American Family Physician. 2006;74:594–600.
  4. 4. Wellbery C. Diagnosis and treatment of endometriosis. American Family Physician. 1999; 60:1753–62.
  5. 5. Barbieri RL, Niloff JM, Bast Jr. RC, Scaetzl E, Kistner RW, Knapp RC. Elevated serum concentrations of CA-125 in patients with advanced endometriosis. Fertil Steril 1986;45:630–4.
  6. 6. May KE, Conduit-Hulbert SA, Villar J, Kirtley S, Kennedy SH, Becker CM. Peripheral biomarkers of endometriosis: a systematic review. Hum Reprod Update 2010;16: 651–74.
  7. 7. Kajihara H, Yamada Y, Kanayama S, Furukawa N, Noguchi T, Haruta S et al. New insights into the pathophysiology of endometriosis: from chronic inflammation to danger signal. Gynecol Endocrinol 2011;27:73–9.
  8. 8. Viganò P, Parazzini F, Somigliana E, Vercellini P. Endometriosis: epidemiology and aetiological factors. Best Pract Res Clin Obstet Gynaecol. 2004;18:177–200.
  9. 9. Yang H, Lang JH, Zhu L, Wang S, Sha GH, Zhang Y. Diagnostic value of the neutrophil-to-lymphocyte ratio and the combination of serum CA-125 for stages III and IV endometriosis. Chin Med J 2013;126:2011-14.
  10. 10. Tazegül A, Acar A. Klinigimizde Gerceklestirilen Histerektomi Olgularının Klinik ve Demografik Ozelliklerinin Degerlendirilmesi. Selçuk Tıp Derg 2010;26:19-22.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Publication Date

July 8, 2020

Submission Date

August 19, 2019

Acceptance Date

December 3, 2019

Published in Issue

Year 2020 Volume: 15 Number: 2

DOI

https://doi.org/10.17517/ksutfd.607197

IZ

https://izlik.org/JA93JW62CH

Cite

RIS / Bibtex
APA
Atıgan, A., & Güler, Ö. T. (2020). Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, 15(2), 20-23. https://doi.org/10.17517/ksutfd.607197
AMA
1.Atıgan A, Güler ÖT. Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis. KSU Medical Journal. 2020;15(2):20-23. doi:10.17517/ksutfd.607197
Chicago
Atıgan, Ayhan, and Ömer Tolga Güler. 2020. “Tumor Markers and Neutrophil-Lymphocyte Ratio’s Predictive Role in Endometriosis”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 15 (2): 20-23. https://doi.org/10.17517/ksutfd.607197.
EndNote
Atıgan A, Güler ÖT (July 1, 2020) Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 15 2 20–23.
IEEE
[1]A. Atıgan and Ö. T. Güler, “Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis”, KSU Medical Journal, vol. 15, no. 2, pp. 20–23, July 2020, doi: 10.17517/ksutfd.607197.
ISNAD
Atıgan, Ayhan - Güler, Ömer Tolga. “Tumor Markers and Neutrophil-Lymphocyte Ratio’s Predictive Role in Endometriosis”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 15/2 (July 1, 2020): 20-23. https://doi.org/10.17517/ksutfd.607197.
JAMA
1.Atıgan A, Güler ÖT. Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis. KSU Medical Journal. 2020;15:20–23.
MLA
Atıgan, Ayhan, and Ömer Tolga Güler. “Tumor Markers and Neutrophil-Lymphocyte Ratio’s Predictive Role in Endometriosis”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, vol. 15, no. 2, July 2020, pp. 20-23, doi:10.17517/ksutfd.607197.
Vancouver
1.Ayhan Atıgan, Ömer Tolga Güler. Tumor markers and neutrophil-lymphocyte ratio’s predictive role in endometriosis. KSU Medical Journal. 2020 Jul. 1;15(2):20-3. doi:10.17517/ksutfd.607197