Evaluation of the Acute and Chronic Effect of Smokeless Tobacco on Anterior Segment Parameters
Abstract
Aim: To evaluate the acute and chronic effects of smokeless tobacco (ST) on the anterior segment parameters using optical biometry.
Material and Method: The comparative study included 53 right eyes of 53 subjects (study group), who used ST and 54 right eyes of 54 healthy subjects without ST (control group). Following a full ophthalmological examination, baseline measurements were taken with optical biometry and these measurements were repeated at 5, 30 and 60 mins after using ST. Central corneal thickness (CCT) (µm), anterior chamber depth (ACD) (mm), lens thickness (LT) (mm), pupillary diameter (PD) (mm), and axial length (AL) (mm) were measured.
Result: No statistical difference between the control group and study group in terms of CCT, AL, ACL and LT (p=0.771, p=0.706, p=0.546, p=0.984, respectively) however, PD values were statistically significantly different (p=0.040) in baseline measurements. In the study group, similary, no statistically significant difference was determined between the measurements taken before and after ST use in respect of CCT, AL, ACD, and LT (p=0.660, p=0.058, p=0.344, p=0.059, respectively). The changes in the PD value with the use of ST were determined to be statistically significant (p<0.01). Thus, the difference in PD value was found to be statistically significant between 5 and 30 mins, between 5 and 60 mins, and between 30 and 60 mins after ST use (p<0.01, p<0.01, p<0.01 respectively).
Conclusion: ST use did not show any acute and chronic effect on CCT, AL, ACD and LT. However, there was seen to be a significant effect on PD.
Keywords
Anterior chamber, optical biometry, pupillar diameter, smokeless tobacco, nicotine
References
- 1) Malovichco MV, Zeller I, Krivokhizhina TV, Xie Z, Lorkiewicz P, Agarwal A, et al. Systemic Toxicity of Smokeless Tobacco Products in Mice. Nicotine Tob Res. 2019 Jan 1;21(1):101-10.
- 2) İnanç Y, Orhan FÖ, İnanç Y. The effects of Maras powder use on patients with migraine. Neuropsychiatr Dis Treat. 2018 May 7;14:1143-8.
- 3) Sucakli MH, Ozkan F, Inci MF, Celik M, Keten HS, Bozoğlan O. Effects of smokeless tobacco (Maras powder) use on carotid intima media thickness. Med Sci Monit. 2013 Oct 16;19:859-64.
- 4) Çömez A, Karaküçük Y, Beyoğlu A. Evaluation of the effect of smokeless tobacco (Maras powder) on choroidal and retinal blood flow: an optical coherence tomography angiography study. Int Ophthalmol. (2020) Jun 40(6):1367-76.
- 5) Kahraman H, Sucaklı MH, Atilla N, Arpağ H, Bozkuş F, Köksal N. The Effect of Working in Smoke-Free Workplace on use of Smoking and Smokeless Tobacco. Turk Thorac J. 2017 Jan;18(1):14-8.
- 6) Aral M, Ekerbicer HC, Celik M, Ciragil P, Gul M. Comparison of effects of smoking and smokless tobacco ‘’Maras powder’’ on immune system parameters. Mediators Inflamm. 2006;2006(3):85019.
- 7) Güven A, Köksal N, Büyükbeşe MA, Cetinkaya A, Sökmen G, Aksu E, et al. Effects of using a different kind of smokeless tobacco on cardiac parameters: ‘’Maras Powder’’. Anadolu Kardiyol Derg.2003 Sep;3(3):230-5.
- 8) Erdem U, Gundogan FC, Dinc UA, Yolcu U, Ilhan A, Altun S. Acute effect of cigarette smoking on pupil size and ocular aberrations: a pre- and postsomoking study. J Ophthalmol. 2015;2015:625470.
- 9) Duman R, Duman R, Sabaner MC, Çetinkaya E. Effect of smoking on the thickness of retinal layers in healthy smokers. Cutan Ocul Toxicol. 2017 Dec;36(4):366-9.
- 10) Dervişoğulları MS, Totan Y, Tenlik A, Yüce A, Güler E. Effect of smoking on retina nerve fiber layer and ganglion cell-inner plexiform layer complex. Cutan Ocul Toxicol. 2015;34(4):282-5.