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Orta Kulak Patolojilerinin ve Bunlara Bağlı İşitme Kayıplarının Geçici Uyarılmış ve Distorsiyon Ürünü Otoakustik Emisyon Değerleri Üzerine Etkisi

Year 2018, Volume: 13 Issue: 1, 19 - 23, 01.03.2018
https://doi.org/10.17517/ksutfd.370606

Abstract

Amaç: İletim tipi işitme kaybına neden olan orta kulak
patolojilerinin, geçici uyarılmış (TEOAE) ve distorsiyon ürünü  (DPOAE) otoakustik emisyon cevapları üzerine
etkisini araştırmak ve bu olgulardan medikal tedavi ve/veya cerrahi tedavi
alanların, tedavi öncesi ve sonrası TEOAE ve DPOAE cevaplarını karşılaştırmak
ve ayrıca klinik odyometrik testlerle OAE testleri arasındaki korelasyonu
araştırmaktır.



Gereç ve Yöntem: Orta kulak problemine bağlı işitme kaybı olan 62
olgunun 107 kulağı çalışmaya alındı. Olguların 31’inde (61 kulak) efüzyonlu
otitis media (EOM), 18’inde (22 kulak) kronik otitis media (KOM), yedisinde (10
kulak) adeziv otitis media, dokuzunda (14 kulak) otoskleroz mevcuttu. İki
olgunun, tek kulağında KOM varken, diğer kulağında adeziv otitis media vardı.
Hastalara saf ses ve konuşma odyometrisi, impedans odyometrisi, TEOAE ve DPOAE
testleri uygulandı. Medikal ve cerrahi tedavi uygulanan olgulara yapılan
testler tekrarlandı.



Bulgular: Olguların ilk gelişlerinde yapılan ortalama saf ses
ortalaması (SSO) ile TEOAE değerleri arasında korelasyon olduğu görüldü (r=-
0,469, p= 0.00). Ortalama SSO ile 1500 Hz, 2000 Hz, 3000 Hz, 4000 Hz, 6000
Hz’lerde ölçülen DPOAE değerleri arasında, ters yönde anlamlı bir korelasyon
olduğu gözlendi (r=-0.356, p= 0.000; r=-0.305, p= 0.001; r=-0.427, p=0.000;
r=-0.238, p=0.000). Ortalama SSO ile 1000 Hz arasında korelasyon saptanmadı (p=
0.064). Farklı frekanslarda ölçülen DPOAE değerleri arasında, 1000 Hz’in diğer
frekanslar ile korelasyon göstermediği tespit edildi. Bin Hz’de ölçülen r ve p
değerleri 1500 Hz için 0,041 ve 0,675; 2000 Hz için -0,008 ve 0,933; 3000 Hz
için 0,186 ve 0,056; 4000 Hz için 0,051 ve 0,601; 6000 Hz için 0,003 ve 0,979
olarak bulundu. EOM’lı kulaklarda, medikal ve cerrahi tedavi öncesi kulakların
% 7’sinde tam TEOAE cevabı alınırken, medikal ve cerrahi tedavi sonrası bu
oranın % 41’e yükseldiği görüldü. Bu olgularda, tedavi sonrası DPOAE
cevaplarının ve amplitüdlerinin arttığı görüldü.

Sonuç: DPOAE testi, yüksek frekanslarda daha güvenilir
sonuçlar vermekte olup, düşük frekanslarda özellikle 1000 Hz’de alınan
cevapların klinik değerlendirmede çok fazla öneminin olmadığı tespit edildi. Orta
kulak patolojilerinin ve orta kulakta basınç azalmasının OAE cevabını
azalttığını ve uygun bir tedavi ile iyileşmeye paralel olarak OAE cevabının
arttığı tespit edildi.

References

  • 1. Erdem T. Otoakustik emisyonların klinikte kullanım alanları (Çeşitli tiplerde işitme kaybı gösteren veya işitme taraması yapılan 166 olgunun 287 kulağı üzerinde yapılan çalışma). Uzmanlık Tezi. İzmir, 1998.
  • 2. Koike KJ, Wetmore SJ. Interactive effects of the middle ear pathology and the associated heariııg loss on transient-evoked otoacoustic emission measures. Otolaryngol Head Neck Surg. 1999;121:238-244.
  • 3. Özturan O, Lew H, Jerger J. Otoakustik emisyonlar ve klinik uygulamaları. KBB İhtisas Dergisi. 1994;2:194-205.
  • 4. Anand Vinod K, McAuley JR, Dickman JD, Malphurs O. Effect of tympanic perforations on the detection of distortion-product otoacoustic emissions. ENT. 2000;79:610-618.
  • 5. Herzog M, Shehata-Dieler WE, Dieler R. Transient evoked and distortion product otoacoustic emissions following successful stapes surgery. Eur Arch Otorhinolaryngol. 2001;258:61-66.
  • 6. Ueda H, Nakata S, Hoshino M. Effects of effusion in the middle ear and perforation of the tympanic membrane on otoacoustic emissions in guinea pigs. Hear Res. 1998;122:41-46.
  • 7. Daya H, Hinton AE, Radomskiej P, Huchzermeyer P. Otoacoustic emissions: assesment of hearing after tympanostomy tube insertion. Clin Otolaryngol. 1996;21:492-494.
  • 8. Zhang M, Abbas PJ. Effects of middle ear pressure on otoacoustic emission measures. J Acoust Soc Am. 1997;102:1032-1037. 9. Akyıldız AN. Kulak Hastalıkları ve Mikrocerrahisi. Cilt I, Bilimsel Tıp Yayınevi, Ankara; 1998.
  • 10. Trine MT, Hirsch JE, Margolis RH. The effect of middle ear pressure on transient evoked otoacoustic emissions. Ear Hear. 1993;14:401-407.
  • 11. Zhao F, Wada H, Koike T, Stephens D. The influence of middle ear disorders on otoacoustic emissions. Clin Otolaryngol. 2000;25:3-8.
  • 12. Chang KW, Vohr BR, Norton SJ, Lekas MD. External and middle ear status related to evoked otoacoustic emission in neonates. Arch Otolaryngol Head Neck Surg. 1993;119:276-282.
  • 13. Yeo SW, Park SN, Park YS, Suh BD. Effect of middle-ear effusion on otoacoustic emissions. J Laryngol Otol. 2002;116:794-799.
  • 14. Koivuen P, Uhari M, Laitakari K, Alho OP, Luotonen J. Otoacoustic emissions and tympanometry in children with otitis media. Ear Hear. 2000;21:212-217.
  • 15. Topolsca MM, Hassman E, Baczek M. The effects of chronic otitis media with effusion on the measurement of distortion products of otoacoustic emissions: presurgical and postsurgical examination. Clin Otolarygol. 2000;25:315-320.
  • 16. Cullington HE, Kumar BU, Flood IM. Feasibility of otoacoustic emission as a hearing screen following grommet insertion. Brit J Audiol. 1998;32:57-62.
  • 17. Richardson HC, Elliott C, Hill J. The feasibility of recording transieııtly evoked otoacoustic emissions immediately following grommet insertion. Clin Otolaryngol. 1996;21:445-448.

The Investigate of Middle Ear Disorders and Hearing Loss Due to Them on Transient Evoked Otoacoustic Emissions and Distortion Product Otoacoustic Emissions.

Year 2018, Volume: 13 Issue: 1, 19 - 23, 01.03.2018
https://doi.org/10.17517/ksutfd.370606

Abstract

Objective:
To investigate the effects of middle ear pathologies on transient evoked
(TEOAE) and distortion product otoacoustic emissions (DPOAE), to compare pre-
and posttreatment TEOAE and DPOAE responses in medically or surgically treated
cases, and to reveal correlations among the results of conventional audiologic
and otoacoustic emission tests.

Materials and methods:
One hundred and seven ears of 62 patients with hearing loss due to middle ear
pathologies were included to this study. Otitis media with effusion was
diagnosed in 31 patients (61 ears), chronic otitis media in 18 patients (22
ears), adhesive otitis media in seven patients (10 ears) and otosclerosis in
nine patients (14 ears). In two cases, chronic otitis media in one ear and
adhesive otitis media in the other ear was observed. Pure tone and speech
audiometric tests, impedence audiometric test, TEOAE and DPOAE tests were
carried out. Patients having otitis media with effusion were followed by using
medical treatment. Ventilation tubes were inserted to 12 patients who had not
responded to medical treatment. In those patients, audiometric and otoacoustic
emission tests were repeated.

Results: A poor
correlation was observed between the pure tone averages and the TEOAE values
obtained on the fırst examination (r= 0.469, p= 0.00). A poor negative
correlation was observed between the pure tone averages and the DPOAE values
that were measured in 1500 Hz, 2000 Hz, 3000 Hz, 4000 Hz, 6000 Hz. r and p
values were -0.356 and 0.000 for 1500 Hz; -0.305 and 0.001 for 2000 Hz; -0.427
and 0.000 for 3000 Hz; -0.238 and 0.014 for 4000 Hz; -0.470 and 0.000 for 6000
Hz. We din’t find any correlation between the pure tone avereges and the DPOAE
values at 1000 Hz (r= -0.180, p=0.064). There was no correlation in the DPOAE
values between the 1000 Hz and the other frequencies. It was observed that
other frequencies were correlated poorly with each other (1500 Hz, 2000 Hz,
3000 Hz, 4000 Hz, 6000 Hz).
Before medical or
surgical treatment, 7 % of patients having otitis media with effussion had
complete TEOAE response. After medical or surgical treatment, the proportion
of
complete response was increased to % 41. In these cases, DPOAE responses and
amplitudes were increased after treatment.







Conclusion: Although DPOAE gives more reliable
results in high frequencies, it is of little benefit in the clinical evaluation
in the low frequencies especially at 1000 Hz. Abnormal pressures and
pathologies in the middle ear decreased OAE responses and the responses were
increased after appropriate treatment.

References

  • 1. Erdem T. Otoakustik emisyonların klinikte kullanım alanları (Çeşitli tiplerde işitme kaybı gösteren veya işitme taraması yapılan 166 olgunun 287 kulağı üzerinde yapılan çalışma). Uzmanlık Tezi. İzmir, 1998.
  • 2. Koike KJ, Wetmore SJ. Interactive effects of the middle ear pathology and the associated heariııg loss on transient-evoked otoacoustic emission measures. Otolaryngol Head Neck Surg. 1999;121:238-244.
  • 3. Özturan O, Lew H, Jerger J. Otoakustik emisyonlar ve klinik uygulamaları. KBB İhtisas Dergisi. 1994;2:194-205.
  • 4. Anand Vinod K, McAuley JR, Dickman JD, Malphurs O. Effect of tympanic perforations on the detection of distortion-product otoacoustic emissions. ENT. 2000;79:610-618.
  • 5. Herzog M, Shehata-Dieler WE, Dieler R. Transient evoked and distortion product otoacoustic emissions following successful stapes surgery. Eur Arch Otorhinolaryngol. 2001;258:61-66.
  • 6. Ueda H, Nakata S, Hoshino M. Effects of effusion in the middle ear and perforation of the tympanic membrane on otoacoustic emissions in guinea pigs. Hear Res. 1998;122:41-46.
  • 7. Daya H, Hinton AE, Radomskiej P, Huchzermeyer P. Otoacoustic emissions: assesment of hearing after tympanostomy tube insertion. Clin Otolaryngol. 1996;21:492-494.
  • 8. Zhang M, Abbas PJ. Effects of middle ear pressure on otoacoustic emission measures. J Acoust Soc Am. 1997;102:1032-1037. 9. Akyıldız AN. Kulak Hastalıkları ve Mikrocerrahisi. Cilt I, Bilimsel Tıp Yayınevi, Ankara; 1998.
  • 10. Trine MT, Hirsch JE, Margolis RH. The effect of middle ear pressure on transient evoked otoacoustic emissions. Ear Hear. 1993;14:401-407.
  • 11. Zhao F, Wada H, Koike T, Stephens D. The influence of middle ear disorders on otoacoustic emissions. Clin Otolaryngol. 2000;25:3-8.
  • 12. Chang KW, Vohr BR, Norton SJ, Lekas MD. External and middle ear status related to evoked otoacoustic emission in neonates. Arch Otolaryngol Head Neck Surg. 1993;119:276-282.
  • 13. Yeo SW, Park SN, Park YS, Suh BD. Effect of middle-ear effusion on otoacoustic emissions. J Laryngol Otol. 2002;116:794-799.
  • 14. Koivuen P, Uhari M, Laitakari K, Alho OP, Luotonen J. Otoacoustic emissions and tympanometry in children with otitis media. Ear Hear. 2000;21:212-217.
  • 15. Topolsca MM, Hassman E, Baczek M. The effects of chronic otitis media with effusion on the measurement of distortion products of otoacoustic emissions: presurgical and postsurgical examination. Clin Otolarygol. 2000;25:315-320.
  • 16. Cullington HE, Kumar BU, Flood IM. Feasibility of otoacoustic emission as a hearing screen following grommet insertion. Brit J Audiol. 1998;32:57-62.
  • 17. Richardson HC, Elliott C, Hill J. The feasibility of recording transieııtly evoked otoacoustic emissions immediately following grommet insertion. Clin Otolaryngol. 1996;21:445-448.
There are 16 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Makaleler
Authors

Saime Sağıroğlu 0000-0003-2608-7274

Mehmet Akif Kılıç This is me

Publication Date March 1, 2018
Submission Date December 25, 2017
Acceptance Date February 19, 2018
Published in Issue Year 2018 Volume: 13 Issue: 1

Cite

AMA Sağıroğlu S, Kılıç MA. Orta Kulak Patolojilerinin ve Bunlara Bağlı İşitme Kayıplarının Geçici Uyarılmış ve Distorsiyon Ürünü Otoakustik Emisyon Değerleri Üzerine Etkisi. KSU Medical Journal. March 2018;13(1):19-23. doi:10.17517/ksutfd.370606