Karpal Tunel Sendromu ve Ortalama Trombosit Hacmi Arasındaki İlişki

Year 2021, Volume: 16 Issue: 2, 178 - 181, 07.07.2021

Fatih Doğar Kaan Gürbüz

https://doi.org/10.17517/ksutfd.810636

Abstract

Amaç:Bu çalışmanın amacı, Karpal Tünel Sendromu (KTS) ile anjiyogenez, tromboz, immünite ve inflamasyonla sonuçlanan ortalama trombosit hacmi (MPV) arasındaki ilişkiyi değerlendirmektir
Gereç ve Yöntemler:2013 ve 2019 yılları arasında, 1660 hastaya mini-açık dekompresyon uygulandı ve sırasıyla 1056 sağlıklı birey kontrol grubu olarak çalışmaya dahil edildi. Dışlama kriterleri sağlandıktan sonra 166 KTS hastası (141 kadın, 25 erkek) ve 156 kontrol hastası (80 kadın, 76 erkek) olarak iki grup belirlendi. KTS ve kontrol gruplarında, 12 saat aç kalındıktan sonar alınan venöz kan örneklerinden MPV, trombositsayısı (PLT), trombosit dağılım genişliği (PDW), beyaz kan hücre (WBC) sayısı, hemoglobin (Hb), ESR ve CRP düzeyleri elde edildi ve hastane veritabanında geriye dönük olarak kaydedildi. Ayrıca KTS grubundaki hastalardan postoperative 6. ve 12. ay kontrollerinde kan örnekleri alınarak operasyon öncesi çalışılan değerler dosyadan tekrardan kaydedildi.
Bulgular:KTS hastaları arasında, ameliyat sonrası 6 ayda ortalama MPV'de bazal değere kıyasla anlamlı bir fark vardı (p = 0,027). Ortalama MPV'de 1. yılda bazal değere göre anlamlı bir fark bulunmadı (p = 0,70). Ek olarak, KTS'li hastalar ve kontroller arasında MPV değerlerinde veya diğer kan parametrelerinde (trombosit sayısı, beyaz kan sayımı, trombosit dağılımı geniş hemoglobin) anlamlı bir fark bulunmadı.
Sonuç:Çalışmamızda KTS ile MPV arasında önemli bir ilişki bulunmadığını tespit ettik. Bu konuyu aydınlatmak için daha büyük örneklem büyüklüğüne ve geniş prospektif çalışmaların gerekli olduğuna inanıyoruz.

Keywords

Karpal Tünel Sendromu, Ortalam Trombosit Hacmi, Trombosit, İlişki

The Relation Between Mean Platelet Volume and Carpal Tunnel Syndrome

Abstract

Objectives:The aim of this study was to evaluate the relationship between Carpal tunnel syndrome (CTS) and mean platelet volume (MPV) in which is raleted with angiogenesis, thrombosis, immunity and inflammation.
Material and Methods:Between 2013 and 2019, 1660 patients underwent mini-open decompression and 1056 healthy individuals were included in the study as study and control grup respectively. After the exclusion criteria are provide, patients were determined 166 CTS patients and 156 control patients in two groups. In the CTS and control groups, MPV, platelet count (PLT), platelet distribution width (PDW), white blood cell(WBC) count, haemoglobin (Hb), ESR and CRP levels were obtained from venous blood samples drawn after 12-h fasting and were recorded retrospectively from the hospital database.In addition, blood samples were taken from the patients in the CTS group at the postoperative 6th and 12th month controls and the values studied before the operation were re-recorded from the file.
Results:Among the CTS patients, only there was a significant difference in the mean MPV at 6 months postoperatively compared to baseline (p=0.027). No significant difference was detected inthe mean MPV at 1 year compared to baseline (p=0.70). In addition, no significant differences were found in MPV values or in other blood parameters (platelet count, white blood count, platelet distribution widthand, haemoglobin) between patients with CTS and controls.
Conclusion:We found that no significant relationship was detected between CTS and MPV in our study. We believe that further prospective studies with larger sample size are needed to elucidate this topic.

Keywords

Carpal Tunnel Syndrome, Mean Platelet Volume, Platelet, Relation.

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