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A Brief Review on Normal Pressure Hydrocephalus Diagnosis in Primary Neuropsychiatric Care Settings

Yıl 2024, Cilt: 19 Sayı: 3, 174 - 180, 04.11.2024
https://doi.org/10.17517/ksutfd.1517990

Öz

Normal pressure hydrocephalus (NPH) is clinically characterized by the triad of mental deterioration, gait disturbance, and urinary incontinence. Correct diagnosis and referral of patients is important because NPH is a potentially treatable cause of cognitive decline and should be distinguished from more common forms of irreversible dementia. Unfortunately, it remains to be a rather underdiagnosed and controversial neuropsychiatric entity even in countries with modern healthcare systems. The diagnostic process is complicated by diverse clinical presentations, especially when the classical triad is incomplete or atypical such as with psychiatric symptoms. This manuscript aims to briefly review atypical clinical presentations of NPH and basic radiologic findings associated with it, and outline some recommendations to primary care physicians for diagnosis and referral.

Kaynakça

  • Adams RD, Fisher CM, Hakim S, Ojemann RG, Sweet WH. Symptomatic occult hydrocephalus with "normal" cerebrospinal-fluid pressure. A treatable syndrome. N Engl J Med. 1965;273:117-126.
  • Bradley WG. Normal pressure hydrocephalus: new concepts on etiology and diagnosis. AJNR Am J Neuroradiol. 2000;21(9):1586-90.
  • Jaraj D, Rabiei K, Marlow T, Jensen C, Skoog I, Wikkelsø C. Prevalence of idiopathic normal-pressure hydrocephalus. Neurology. 2014;82(16):1449-1454.
  • Rigamonti D, Yasar S, Vivas-Buitrago T, Rigamonti K. Letter to our colleagues family practitioners, geriatricians, and radiologists to increase awareness regarding idiopathic normal pressure hydrocephalus. World Neurosurg. 2024;181:e291-e293.
  • Singh G, Sharma R, Catchpoole S, et al. Normal pressure hydrocephalus. Reference article, Radiopaedia.org (Accessed on 10 Jul 2024) https://doi.org/10.53347/rID-6306.
  • Hurley R, Bradley W, Latifi H, Taber K. Normal pressure hydrocephalus: significance of MRI in a potentially treatable dementia. J Neuropsychiatry Clin Neurosci. 1999;11(3):297-300.
  • Damasceno BP. Neuroimaging in normal pressure hydrocephalus. Dement Neuropsychol. 2015;9(4):350-355.
  • Andersson J, Rosell M, Kockum K, Lilja-Lund O, Söderström L, Laurell K. Prevalence of idiopathic normal pressure hydrocephalus: A prospective, population-based study. PLoS One. 2019;14(5):e0217705.
  • Iseki C, Kawanami T, Nagasawa H et al. Asymptomatic ventriculomegaly with features of idiopathic normal pressure hydrocephalus on MRI (AVIM) in the elderly: A prospective study in a Japanese Population. J Neurol Sci. 2009;277(1-2):54-57.
  • Iseki C, Takahashi Y, Wada M, Kawanami T, Adachi M, Kato T. Incidence of idiopathic normal pressure hydrocephalus (iNPH): a 10-year follow-up study of a rural community in Japan. J Neurol Sci. 2014;339(1-2):108-112.
  • Brean A, Eide PK. Prevalence of probable idiopathic normal pressure hydrocephalus in a Norwegian population. Acta Neurol Scand. 2008;118(1):48-53.
  • Shprecher D, Schwalb J, Kurlan R. Normal pressure hydrocephalus: Diagnosis and treatment. Curr Neurol Neurosci Rep. 2008;8(5):371-376.
  • Pinner G, Johnson H, Bouman WP, Isaacs J. Psychiatric manifestations of normal-pressure hydrocephalus: a short review and unusual case. Int Psychogeriatr. 1997;9(4):465-470.
  • Alao AO, Naprawa SA. Psychiatric complications of hydrocephalus. Int J Psychiatry Med. 2001;31(3):337-340.
  • Lying-Tunell U. Psychotic symptoms in normal-pressure hydrocephalus. Acta Psychiatr Scand. 1979;59(4):415-419.
  • Vanhala V, Junkkari A, Korhonen VE, et al. Prevalence of schizophrenia in idiopathic normal pressure hydrocephalus. Neurosurgery. 2019;84(4):883-889.
  • Yoshino Y, Yoshida T, Morino H, et al. Prevalence of possible idiopathic normal pressure hydrocephalus in older inpatients with schizophrenia: a replication study. BMC Psychiatry. 2020;20(1):273.
  • Rice E, Gendelman S. Psychiatric aspects of normal pressure hydrocephalus. JAMA. 1973;223(4):409-412.
  • Manoj PM, Alam MR. Normal pressure hydrocephalus disguising psychosis: a case report. East Asian Arch Psychiatry. 2024;34(2):45-47.
  • Yusim A, Anbarasan D, Bernstein C, Boksay I, Dulchin M, Lindenmayer JP, et al. Normal pressure hydrocephalus presenting as Othello syndrome: Case presentation and review of the literature. Am J Psychiatry. 2008;165(9):1119-1125.
  • Lamjoun M, Jelti A, Elghazouani F, Barrimi M. Normal pressure hydrocephalus and mania symptoms: Case report. Radiol Case Rep. 2023;18(7):2397-2400.
  • Rivkin M, Banerjee S, Guan T, Hendrix C. The importance of primary care cognitive evaluation in detecting an atypical presentation of normal pressure hydrocephalus. Cureus. 2024;16(6):e62166.
  • Bradley WG. Normal pressure hydrocephalus: new concepts on etiology and diagnosis. AJNR Am J Neuroradiol. 2000;21(9):1586-1590.
  • Oliveira LM, Nitrini R, Román GC. Normal-pressure hydrocephalus: A critical review. Dement Neuropsychol. 2019 Apr-Jun;13(2):133-143.
  • Stöcklein SM, Brandlhuber M, Lause SS, Pomschar A, Jahn K, Schniepp R, et al. Decreased craniocervical CSF flow in patients with normal pressure hydrocephalus: A pilot study. AJNR Am J Neuroradiol. 2022;43(2):230-237.
  • Thomas G, McGirt MJ, Woodworth G, Heidler J, Rigamonti D, Hillis AE, et al. Baseline neuropsychological profile and cognitive response to cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus. Dement Geriatr Cogn Disord. 2005;20(2-3):163-168.
  • Hellström P, Klinge P, Tans J, Wikkelsø C. The neuropsychology of iNPH:Findings and evaluation of tests in the European multicentre study. Clin Neurol Neurosurg. 2012;114(2):130-134.
  • Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM. Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery. 2005;57(3 Suppl):S4-16.
  • Andersson J, Rosell M, Kockum K, Söderström L, Laurell K. Challenges in diagnosing normal pressure hydrocephalus: Evaluation of the diagnostic guidelines. eNeurologicalSci. 2017 Apr 11;7:27-31.
  • Klinge P, Hellström P, Tans J, Wikkelsø C; European iNPH Multicentre Study Group. One-year outcome in the European multicentre study on iNPH. Acta Neurol Scand. 2012;126(3):145-153.
  • Kimura T, Yamada S, Sugimura T, Seki T, Miyano M, Fukuda S, et al. Preoperative predictive factors of short-term outcome in idiopathic normal pressure hydrocephalus. World Neurosurg. 2021;151:e399-e406.
  • Giordan E, Palandri G, Lanzino G, Murad MH, Elder BD. Outcomes and complications of different surgical treatments for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis. J Neurosurg. 2018;131(4):1024-1036.
  • Gallia GL, Rigamonti D, Williams MA. The diagnosis and treatment of idiopathic normal pressure hydrocephalus. Nat Clin Pract Neurol. 2006;2(7):375-81.
  • Williams MA, Malm J. Diagnosis and treatment of idiopathic normal pressure hydrocephalus. Continuum (Minneap Minn). 2016;22(2):579-599.
  • Cai H, Zou Y, Gao H, Huang K, Liu Y, Cheng Y, Liu Y, Zhou L, Zhou D, Chen Q. Radiological biomarkers of idiopathic normal pressure hydrocephalus: new approaches for detecting concomitant Alzheimer's disease and predicting prognosis. Psychoradiology. 2022;2(4):156-170.
  • Brix MK, Westman E, Simmons A, Ringstad GA, Eide PK, Wagner-Larsen K, et al. The Evans' index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly. Eur J Radiol. 2017;95:28-32.
  • Ishii K, Kanda T, Harada A et-al. Clinical impact of the callosal angle in the diagnosis of idiopathic normal pressure hydrocephalus. Eur Radiol. 2008;18 (11): 2678-2683.
  • Virhammar J, Laurell K, Cesarini KG, Larsson EM. The callosal angle measured on MRI as a predictor of outcome in idiopathic normal-pressure hydrocephalus. J. Neurosurg. 2014;120(1): 178-184.
  • Virhammar J, Laurell K, Cesarini KG, Larsson EM. Preoperative prognostic value of MRI findings in 108 patients with idiopathic normal pressure hydrocephalus. AJNR Am J Neuroradiol. 2014;35(12):2311-8.
  • Hagberg EE, Tisell M, Farahmand D, Arvidsson L. ABC om idiopatisk normaltryckshydrocefalus [Swedish]. Läkartidningen. 2022;119:22044.

Birinci Basamak Nöropsikiyatrik Bakım Hizmetlerinde Normal Basınçlı Hidrosefali Tanısına İlişkin Kısa Bir Derleme

Yıl 2024, Cilt: 19 Sayı: 3, 174 - 180, 04.11.2024
https://doi.org/10.17517/ksutfd.1517990

Öz

Normal basınçlı hidrosefali klinik olarak zihinsel bozulma, yürüme bozukluğu ve idrar kaçırma üçlüsü ile karakterizedir. Kognitif gerilemenin potansiyel olarak tedavi edilebilir olması nedeniyle diğer daha yaygın, ancak geri dönüşsüz, demans türlerinden ayırt edilmesi gerekmektedir. Normal basınçlı hidrosefali, öte yandan, modern sağlık sistemlerine sahip ülkelerde bile beklenenden az tanı konulan bir nöropsikiyatrik antite olmaya devam etmektedir. Özellikle klasik semptom üçlüsünün gözlenmediği veya psikiyatrik semptomlar gibi atipik semptomlarla prezente olan hastalarda tanısal süreç daha da karmaşık hale gelmektedir. Bu yazıda normal basınçlı hidrosefalinin atipik klinik belirtileri ve temel radyolojik bulguları kısaca gözden geçirilmekte, ve birinci basamakta tanı ve tedavi zincirinin başlatılması için bazı öneriler özetlenmektedir.

Kaynakça

  • Adams RD, Fisher CM, Hakim S, Ojemann RG, Sweet WH. Symptomatic occult hydrocephalus with "normal" cerebrospinal-fluid pressure. A treatable syndrome. N Engl J Med. 1965;273:117-126.
  • Bradley WG. Normal pressure hydrocephalus: new concepts on etiology and diagnosis. AJNR Am J Neuroradiol. 2000;21(9):1586-90.
  • Jaraj D, Rabiei K, Marlow T, Jensen C, Skoog I, Wikkelsø C. Prevalence of idiopathic normal-pressure hydrocephalus. Neurology. 2014;82(16):1449-1454.
  • Rigamonti D, Yasar S, Vivas-Buitrago T, Rigamonti K. Letter to our colleagues family practitioners, geriatricians, and radiologists to increase awareness regarding idiopathic normal pressure hydrocephalus. World Neurosurg. 2024;181:e291-e293.
  • Singh G, Sharma R, Catchpoole S, et al. Normal pressure hydrocephalus. Reference article, Radiopaedia.org (Accessed on 10 Jul 2024) https://doi.org/10.53347/rID-6306.
  • Hurley R, Bradley W, Latifi H, Taber K. Normal pressure hydrocephalus: significance of MRI in a potentially treatable dementia. J Neuropsychiatry Clin Neurosci. 1999;11(3):297-300.
  • Damasceno BP. Neuroimaging in normal pressure hydrocephalus. Dement Neuropsychol. 2015;9(4):350-355.
  • Andersson J, Rosell M, Kockum K, Lilja-Lund O, Söderström L, Laurell K. Prevalence of idiopathic normal pressure hydrocephalus: A prospective, population-based study. PLoS One. 2019;14(5):e0217705.
  • Iseki C, Kawanami T, Nagasawa H et al. Asymptomatic ventriculomegaly with features of idiopathic normal pressure hydrocephalus on MRI (AVIM) in the elderly: A prospective study in a Japanese Population. J Neurol Sci. 2009;277(1-2):54-57.
  • Iseki C, Takahashi Y, Wada M, Kawanami T, Adachi M, Kato T. Incidence of idiopathic normal pressure hydrocephalus (iNPH): a 10-year follow-up study of a rural community in Japan. J Neurol Sci. 2014;339(1-2):108-112.
  • Brean A, Eide PK. Prevalence of probable idiopathic normal pressure hydrocephalus in a Norwegian population. Acta Neurol Scand. 2008;118(1):48-53.
  • Shprecher D, Schwalb J, Kurlan R. Normal pressure hydrocephalus: Diagnosis and treatment. Curr Neurol Neurosci Rep. 2008;8(5):371-376.
  • Pinner G, Johnson H, Bouman WP, Isaacs J. Psychiatric manifestations of normal-pressure hydrocephalus: a short review and unusual case. Int Psychogeriatr. 1997;9(4):465-470.
  • Alao AO, Naprawa SA. Psychiatric complications of hydrocephalus. Int J Psychiatry Med. 2001;31(3):337-340.
  • Lying-Tunell U. Psychotic symptoms in normal-pressure hydrocephalus. Acta Psychiatr Scand. 1979;59(4):415-419.
  • Vanhala V, Junkkari A, Korhonen VE, et al. Prevalence of schizophrenia in idiopathic normal pressure hydrocephalus. Neurosurgery. 2019;84(4):883-889.
  • Yoshino Y, Yoshida T, Morino H, et al. Prevalence of possible idiopathic normal pressure hydrocephalus in older inpatients with schizophrenia: a replication study. BMC Psychiatry. 2020;20(1):273.
  • Rice E, Gendelman S. Psychiatric aspects of normal pressure hydrocephalus. JAMA. 1973;223(4):409-412.
  • Manoj PM, Alam MR. Normal pressure hydrocephalus disguising psychosis: a case report. East Asian Arch Psychiatry. 2024;34(2):45-47.
  • Yusim A, Anbarasan D, Bernstein C, Boksay I, Dulchin M, Lindenmayer JP, et al. Normal pressure hydrocephalus presenting as Othello syndrome: Case presentation and review of the literature. Am J Psychiatry. 2008;165(9):1119-1125.
  • Lamjoun M, Jelti A, Elghazouani F, Barrimi M. Normal pressure hydrocephalus and mania symptoms: Case report. Radiol Case Rep. 2023;18(7):2397-2400.
  • Rivkin M, Banerjee S, Guan T, Hendrix C. The importance of primary care cognitive evaluation in detecting an atypical presentation of normal pressure hydrocephalus. Cureus. 2024;16(6):e62166.
  • Bradley WG. Normal pressure hydrocephalus: new concepts on etiology and diagnosis. AJNR Am J Neuroradiol. 2000;21(9):1586-1590.
  • Oliveira LM, Nitrini R, Román GC. Normal-pressure hydrocephalus: A critical review. Dement Neuropsychol. 2019 Apr-Jun;13(2):133-143.
  • Stöcklein SM, Brandlhuber M, Lause SS, Pomschar A, Jahn K, Schniepp R, et al. Decreased craniocervical CSF flow in patients with normal pressure hydrocephalus: A pilot study. AJNR Am J Neuroradiol. 2022;43(2):230-237.
  • Thomas G, McGirt MJ, Woodworth G, Heidler J, Rigamonti D, Hillis AE, et al. Baseline neuropsychological profile and cognitive response to cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus. Dement Geriatr Cogn Disord. 2005;20(2-3):163-168.
  • Hellström P, Klinge P, Tans J, Wikkelsø C. The neuropsychology of iNPH:Findings and evaluation of tests in the European multicentre study. Clin Neurol Neurosurg. 2012;114(2):130-134.
  • Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM. Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery. 2005;57(3 Suppl):S4-16.
  • Andersson J, Rosell M, Kockum K, Söderström L, Laurell K. Challenges in diagnosing normal pressure hydrocephalus: Evaluation of the diagnostic guidelines. eNeurologicalSci. 2017 Apr 11;7:27-31.
  • Klinge P, Hellström P, Tans J, Wikkelsø C; European iNPH Multicentre Study Group. One-year outcome in the European multicentre study on iNPH. Acta Neurol Scand. 2012;126(3):145-153.
  • Kimura T, Yamada S, Sugimura T, Seki T, Miyano M, Fukuda S, et al. Preoperative predictive factors of short-term outcome in idiopathic normal pressure hydrocephalus. World Neurosurg. 2021;151:e399-e406.
  • Giordan E, Palandri G, Lanzino G, Murad MH, Elder BD. Outcomes and complications of different surgical treatments for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis. J Neurosurg. 2018;131(4):1024-1036.
  • Gallia GL, Rigamonti D, Williams MA. The diagnosis and treatment of idiopathic normal pressure hydrocephalus. Nat Clin Pract Neurol. 2006;2(7):375-81.
  • Williams MA, Malm J. Diagnosis and treatment of idiopathic normal pressure hydrocephalus. Continuum (Minneap Minn). 2016;22(2):579-599.
  • Cai H, Zou Y, Gao H, Huang K, Liu Y, Cheng Y, Liu Y, Zhou L, Zhou D, Chen Q. Radiological biomarkers of idiopathic normal pressure hydrocephalus: new approaches for detecting concomitant Alzheimer's disease and predicting prognosis. Psychoradiology. 2022;2(4):156-170.
  • Brix MK, Westman E, Simmons A, Ringstad GA, Eide PK, Wagner-Larsen K, et al. The Evans' index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly. Eur J Radiol. 2017;95:28-32.
  • Ishii K, Kanda T, Harada A et-al. Clinical impact of the callosal angle in the diagnosis of idiopathic normal pressure hydrocephalus. Eur Radiol. 2008;18 (11): 2678-2683.
  • Virhammar J, Laurell K, Cesarini KG, Larsson EM. The callosal angle measured on MRI as a predictor of outcome in idiopathic normal-pressure hydrocephalus. J. Neurosurg. 2014;120(1): 178-184.
  • Virhammar J, Laurell K, Cesarini KG, Larsson EM. Preoperative prognostic value of MRI findings in 108 patients with idiopathic normal pressure hydrocephalus. AJNR Am J Neuroradiol. 2014;35(12):2311-8.
  • Hagberg EE, Tisell M, Farahmand D, Arvidsson L. ABC om idiopatisk normaltryckshydrocefalus [Swedish]. Läkartidningen. 2022;119:22044.
Toplam 40 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Derlemeler
Yazarlar

Abdullah Yıldırım 0000-0003-2026-1673

Derya Türeli 0000-0003-4784-3294

Erken Görünüm Tarihi 23 Ekim 2024
Yayımlanma Tarihi 4 Kasım 2024
Gönderilme Tarihi 18 Temmuz 2024
Kabul Tarihi 9 Ağustos 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 19 Sayı: 3

Kaynak Göster

AMA Yıldırım A, Türeli D. A Brief Review on Normal Pressure Hydrocephalus Diagnosis in Primary Neuropsychiatric Care Settings. KSÜ Tıp Fak Der. Kasım 2024;19(3):174-180. doi:10.17517/ksutfd.1517990