Rize Bölgesindeki Gebelerde Emesis Gravidarum Prevalansı
Year 2025,
Volume: 20 Issue: 3, 211 - 214
Mehmet Kağıtcı
,
Senol Senturk
,
Deniz Dereci Delibaş
,
Nalan Kuruca
,
Mehmet Kıvrak
Abstract
Objective: Nausea and vomiting of pregnancy (NVP) are frequently encountered in pregnancy and can lead to serious maternal and fetal complications if neglected. This study aims to determine the frequency of NVP and related factors in Rize.
Material and Methods: In this prospective study, the severity and frequency of NVP were determined by scoring pregnant women between 5-20 weeks of gestation, using the Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scoring system. Pregnant women with a PUQUE score below 7 were defined as the mild NVP group, and a score of 7 and above was defined as the moderate and severe NVP group. Demographic data and blood electrolyte levels were compared between the two groups.
Results: A total of 221 pregnant women were included. The frequency of moderate-severe NVP was found to be 10% (n = 22). The frequency of hyperemesis gravidarum was 2% (n=4). The average body mass index of pregnant women with moderate-severe NVP symptoms was found to be higher than that of pregnant women with mild symptoms (p<0.001). The average blood sodium and potassium levels of pregnant women with moderate-severe NVP were found to be lower (p=0.003 and <0.001).
Conclusion: The frequency of NVP in Rize province is similar to the literature. Increased body mass index may be associated with the frequency of NVP. Electrolyte imbalances may occur in the blood of these pregnant women. For this reason, all pregnant women should be carefully evaluated in terms of NVP, and treatments should be planned to eliminate electrolyte imbalances in patients.
References
-
Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018; 131(1):e15-e30.
-
Joshi A, Chadha G, Narayanan P. From Discomfort to Distress: A Critical Analysis of Hyperemesis Gravidarum in the Emergency Room. Cureus. 2023; 15(8):e44004.
-
Festin M. Nausea and vomiting in early pregnancy. BMJ Clin Evid. 2014 Mar 19;2014:1405.
-
Liu C, Zhao G, Qiao D, Wang L, He Y, Zhao M, Fan Y, Jiang E. Emerging Progress in Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum: Challenges and Opportunities. Front Med (Lausanne). 2022 Jan 10;8:809270.
-
Nacar G, Derman G, Güzel İnal C. Hiperemezis Gravidarumlu Gebelerde Depresif Semptomlar ve Kişilik Özelliklerinin Bulantı Kusma Şiddeti ile İlişkisi. JSHS. 2023;8(2):323-338.
-
Verberg MF, Gillott DJ, Al-Fardan N, Grudzinskas JG. Hyperemesis gravidarum, a literature review [published correction appears in Hum Reprod Update. 2007 Mar-Apr; 13(2):207]. Hum Reprod Update. 2005;11(5):527-539.
-
Lacasse A, Rey E, Ferreira E, Morin C, Bérard A. Validity of a modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scoring index to assess severity of nausea and vomiting of pregnancy. Am J Obstet Gynecol. 2008 Jan;198(1):71.
-
Yilmaz T, Dinç Kaya H, Günaydin S, Güdücü N, Dişsiz M. Psychometric properties of the Pregnancy-Unique Quantification of Emesis (PUQE-24) Scale. J Obstet Gynaecol. 2022 Aug;42(6):1739-1745.
-
Fejzo MS, Trovik J, Grooten IJ, Sridharan K, Roseboom TJ, Vikanes Å, et al. Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nature reviews. Disease primers. 2019;5(1):62.
-
Dekkers GW F, Broeren MAC, Truijens SEM, Kop WJ, Pop VJM. Hormonal and psychological factors in nausea and vomiting during pregnancy. Psychological Medicine. 2020; 50(2), 229-236.
-
Topçu H, Can İ, Oskovi A, Timur H, Dağlar K, Danışman N. Risk Factors of Prolonged Hospitalization in Patients With Hyperemesis Gravidarum. Cukurova Medical Journal, 2015;40(1):113-118.
-
Davis, Mitzi. "Nausea and vomiting of pregnancy: an evidence-based review." The Journal of perinatal & neonatal nursing 2004;18.4:312-328.
-
Body C, Christie JA. Gastrointestinal Diseases in Pregnancy: Nausea, Vomiting, Hyperemesis Gravidarum, Gastroesophageal Reflux Disease, Constipation, and Diarrhea. Gastroenterol Clin North Am. 2016;45(2):267-283.
-
Shaban MM, Kandil HO, Elshafei AH. Helicobacter pylori seropositivity in patients with hyperemesis gravidarum. Am J Med Sci. 2014 Feb;347(2):101-5.
-
Abramowitz A, Miller ES, Wisner KL. Treatment options for hyperemesis gravidarum. Arch Womens Ment Health. 2017 Jun; 20(3):363-372.
-
Summers A. Emergency management of hyperemesis gravidarum. Emerg Nurse. 2012 Jul; 20(4):24-28.
Rize Bölgesindeki Gebelerde Emesis Gravidarum Prevalansı
Year 2025,
Volume: 20 Issue: 3, 211 - 214
Mehmet Kağıtcı
,
Senol Senturk
,
Deniz Dereci Delibaş
,
Nalan Kuruca
,
Mehmet Kıvrak
Abstract
Amaç: Gebelikte bulantı ve kusma (NVP) gebelikte sıklıkla karşılaşılan bir durumdur ve ihmal edilirse ciddi maternal ve fetal komplikasyonlara yol açabilir. Bu çalışmanın amacı Rize'de NVP sıklığını ve ilgili faktörleri belirlemektir.
Gereç ve Yöntemler: Bu prospektif çalışmada, NVP şiddeti ve sıklığı, 5-20 gebelik haftası arasındaki gebelerde, Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) skorlama sistemi kullanılarak puanlanarak belirlendi. PUQUE skoru 7'nin altında olan gebeler hafif NVP grubu, 7 ve üzeri olan gebeler ise orta ve şiddetli NVP grubu olarak tanımlandı. Demografik veriler ve kan elektrolit seviyeleri her iki grup arasında karşılaştırıldı.
Bulgular: Toplam 221 gebe kadın çalışmaya dahil edildi. Orta-şiddetli NVP sıklığı %10 (n=22) olarak bulundu. Hiperemesis gravidarum sıklığı %2 (n=4) olarak bulundu. Orta-şiddetli NVP semptomları olan gebelerin ortalama vücut kitle indeksi, hafif semptomları olan gebelerden daha yüksek bulundu (p<0,001). Orta-şiddetli NVP semptomları olan gebelerin ortalama kan sodyum ve potasyum düzeyleri daha düşük bulundu (p=0,003 ve <0.001).
Sonuç: Rize ilinde NVP sıklığı literatürle benzerdir. Vücut kitle indeksinin artması NVP sıklığı ile ilişkili olabilir. Bu gebelerde kanda elektrolit dengesizlikleri görülebilir. Bu nedenle tüm gebeler NVP açısından dikkatlice değerlendirilmeli ve gerekli hastalarda elektrolit dengesizliklerini ortadan kaldırmaya yönelik tedaviler planlanmalıdır.
References
-
Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018; 131(1):e15-e30.
-
Joshi A, Chadha G, Narayanan P. From Discomfort to Distress: A Critical Analysis of Hyperemesis Gravidarum in the Emergency Room. Cureus. 2023; 15(8):e44004.
-
Festin M. Nausea and vomiting in early pregnancy. BMJ Clin Evid. 2014 Mar 19;2014:1405.
-
Liu C, Zhao G, Qiao D, Wang L, He Y, Zhao M, Fan Y, Jiang E. Emerging Progress in Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum: Challenges and Opportunities. Front Med (Lausanne). 2022 Jan 10;8:809270.
-
Nacar G, Derman G, Güzel İnal C. Hiperemezis Gravidarumlu Gebelerde Depresif Semptomlar ve Kişilik Özelliklerinin Bulantı Kusma Şiddeti ile İlişkisi. JSHS. 2023;8(2):323-338.
-
Verberg MF, Gillott DJ, Al-Fardan N, Grudzinskas JG. Hyperemesis gravidarum, a literature review [published correction appears in Hum Reprod Update. 2007 Mar-Apr; 13(2):207]. Hum Reprod Update. 2005;11(5):527-539.
-
Lacasse A, Rey E, Ferreira E, Morin C, Bérard A. Validity of a modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scoring index to assess severity of nausea and vomiting of pregnancy. Am J Obstet Gynecol. 2008 Jan;198(1):71.
-
Yilmaz T, Dinç Kaya H, Günaydin S, Güdücü N, Dişsiz M. Psychometric properties of the Pregnancy-Unique Quantification of Emesis (PUQE-24) Scale. J Obstet Gynaecol. 2022 Aug;42(6):1739-1745.
-
Fejzo MS, Trovik J, Grooten IJ, Sridharan K, Roseboom TJ, Vikanes Å, et al. Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nature reviews. Disease primers. 2019;5(1):62.
-
Dekkers GW F, Broeren MAC, Truijens SEM, Kop WJ, Pop VJM. Hormonal and psychological factors in nausea and vomiting during pregnancy. Psychological Medicine. 2020; 50(2), 229-236.
-
Topçu H, Can İ, Oskovi A, Timur H, Dağlar K, Danışman N. Risk Factors of Prolonged Hospitalization in Patients With Hyperemesis Gravidarum. Cukurova Medical Journal, 2015;40(1):113-118.
-
Davis, Mitzi. "Nausea and vomiting of pregnancy: an evidence-based review." The Journal of perinatal & neonatal nursing 2004;18.4:312-328.
-
Body C, Christie JA. Gastrointestinal Diseases in Pregnancy: Nausea, Vomiting, Hyperemesis Gravidarum, Gastroesophageal Reflux Disease, Constipation, and Diarrhea. Gastroenterol Clin North Am. 2016;45(2):267-283.
-
Shaban MM, Kandil HO, Elshafei AH. Helicobacter pylori seropositivity in patients with hyperemesis gravidarum. Am J Med Sci. 2014 Feb;347(2):101-5.
-
Abramowitz A, Miller ES, Wisner KL. Treatment options for hyperemesis gravidarum. Arch Womens Ment Health. 2017 Jun; 20(3):363-372.
-
Summers A. Emergency management of hyperemesis gravidarum. Emerg Nurse. 2012 Jul; 20(4):24-28.