Rare Side Effects After Inactiveted Sars-Cov-2 Vaccine (Coronavac)

Year 2022, , 142 - 145, 14.03.2022

Tuğba Songül Tat Vuslat Boşnak , Gülşah Bayçelebi

https://doi.org/10.18521/ktd.1061482

Abstract

Objective
To evaluate the frequency, type, onset time, and intensity of the side effects after the Coronavac vaccination in healthcare workers (HCW) and elderly people and also to determine whether COVID-19 disease occurs after vaccination in HCW.
Methods
HCW and elderly people who were vaccinated in XXXXXXX Medical Park were the cohorts of the study. A questionnaire was applied to HCW, and the data of elderly people were obtained from medical records. The questionnaire had demographic data, medical history also included COVID-19-related and side effects of the Coronavac vaccine.
Results
427 questionnaires were analyzed. The most common adverse reaction was pain at the injection site. The incidences of pain after the first and second injections were 22.3% (102/457) and 12,8% (52/405), respectively. And most common systemic side effect was fatigue with an incidence of 18.2% and 10.3% after each dose, respectively. Side effects that kept HCW from going to work after vaccination were not observed. After the two doses of vaccination, only 7 HCW had mild COVID-19 infection. One had a COVID-19 infection after 7 days of the first dose. 354 medical records of elderly people were evaluated. Only one of them reported urticaria after the first dose.
Conclusion
Our study found that Coronavac is a well-tolerated vaccine.

Keywords

Adverse reaction, Coronavac, COVID-19 vaccination, inactivated vaccine, healthcare workers vaccination, safety, side effects

Supporting Institution

Mevcut değil.

Project Number

-

Thanks

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İnaktive Sars-Cov-2 (Coronavac) Aşısı Sonrası Nadir Görülen Yan Etkiler

Abstract

Amaç
Sağlık çalışanları ve yaşlılarda Coronavac aşılamasından sonraki yan etkilerin sıklığını, tipini, başlangıç zamanını ve yoğunluğunu değerlendirmek ve ayrıca sağlık çalışanlarında aşılamadan sonra COVID-19 hastalığının oluşup oluşmadığını belirlemektir.
Metod
Çalışmanın kohortunu xxxxxxx Medical Park hastanesinde aşılanan sağlık çalışanları ve yaşlı kişiler oluşturmaktadır. Coronovac ile aşılanan yaşlı kişilerin verileri tıbbi kayıtlardan elde edildi. Sağlık çalışanlarına, demografik veriler, COVID-19 ile de ilişkili olan tıbbi öykü ve Coronavac aşısının yan etkilerini içeren bir anket uygulandı.
Bulgular
427 anket analiz edildi. En sık görülen yan etki enjeksiyon bölgesinde ağrıydı. Birinci ve ikinci enjeksiyon sonrası ağrı insidansı sırasıyla %22.3 (102/457) ve %12,8 (52/405) idi. En sık görülen sistemik yan etki, birinci dozdan sonra %18.2 ve ikinci dozdan sonra %10.3 insidansı ile yorgunluk idi. Aşılamadan sonra sağlık çalışanlarının işe gitmesini engelleyen yan etkiler gözlenmedi. İki doz aşılamadan sonra, sadece 7 sağlık çalışanında hafif COVID-19 enfeksiyonu tespit edildi. Bir kişide ilk dozdan 7 gün sonra COVID-19 enfeksiyonu görüldü. 354 yaşlı kişiye ait tıbbi kayıtlar değerlendirildi ve bu kişilerden sadece bir tanesinde ilk dozdan sonra ürtiker tespit edildi.
Sonuç
Çalışmamızda Coronavac'ın iyi tolere edilen bir aşı olduğu bulunmuştur.

Keywords

Yan etkiler, Coronavac, COVID-19 aşısı, inaktive aşı, sağlık çalışanları aşılaması, güvenlik, istenmeyen etkiler

Project Number

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