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Abstract

Aim: Mineral Trioxide Aggregate (MTA) is widely used in clinical application such as pulp capping, perforation repair, root-end sealing, canal filling at internal and external root resorption and pulpotomies in primary and permanent teeth. In endodontic field when using a material such as MTA the interaction between material and periapical tissue is so important for healing and life time of endodontic therapy. Although it is sealing ability, the interaction with cells or tissues and their replay to this material play major role for endodontic success. Methods: Literature review was performed using electronic and hand-searching methods for the clinical applications, experimental studies and cellular studies of MTA between 2000 and 2010. Results: MTA is a bioactive material when using vital pulpotomies, apical barrier formation for necrotic pulps and open apices. Numerous study and case reports show MTA is more effective material than other materials in these cases. Many studies have shown the effects of MTA on cementoblasts and odontoblasts. Conclusion: This review shows its composition, biologic action when used different endodontic procedure and interaction between cell and tissues

Keywords

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Mineral Trioksid Aggregate'ın Kompozisyonu ve Biyolojik Etkileri: Derleme

Abstract

Amaç: Mineral trioksit Aggregat pulpa kapamasında, perforasyon tedavisinde, rezorpsyonlarda ve pulpotomilerde kanal dolgu materyali olarak kullanılmaktadır. Endodontide MTA gibi bir materyal kullanıldığı zaman, materyal ve doku etkileşimi sonrasında iyileşme ve endodontik tedavinin ömrü açısından çok önemlidir. Kapama yeteneği hücre ve dokularla etkileşimleri ve bu materyale gösterdikleri yanıtlar endodontik başarıda önemli rol oynar. Gereç ve Yöntem: MTA ile ilgili literatür taraması 2000-2011 arasında yapılmış klinik, deneysel ve hücresel çalışmalar için elektronik tarama ve dergi taraması yapılmıştır. Bulgular: MTA vital pulpotomilerde, nekrotik pulpaların apikal bariyerini oluşturmak için, açık apeksleri kapamak için kullanılan biyoaktif materyaldir. Pek çok yayında ve olgu sunumlarında MTA’nın diğer materyallerden daha etkili olduğu gösterilmiştir. MTA’nın sementoblast ve odontoblastlara etkili olduğunu gösteren yayınlarda mevcuttur. Sonuç: Bu yayında MTA’nın kompozisyonu, farklı endodontik uygulamalarda kullanımında biyolojik etkisi ve hücre ve dokularla etkileşimi gösterilmektedir

Keywords

• Biyolojik Etki, Mineral Trioksit Aggregat, MTA, Hücre

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