Year 2026,
Volume: 18 Issue: 1, 98 - 103, 24.03.2026
Şeyma Ceylan
,
İsmail Arslan
References
-
1. Management of premenstrual disorders: ACOG clinical practice guideline no. 7. Obstet Gynecol. 2023;142(6):1516-33. doi:10.1097/AOG.0000000000005426.
-
2. Modzelewski S, Oracz A, Żukow X, Iłendo K, Śledzikowka Z, Waszkiewicz N. Premenstrual syndrome: new insights into etiology and review of treatment methods. Front Psychiatry. 2024;15:1363875. doi:10.3389/fpsyt.2024.1363875.
-
3. Gao M, Zhang H, Gao Z, Cheng X, Sun Y, Qiao M, et al. Global and regional prevalence and burden for premenstrual syndrome and premenstrual dysphoric disorder: a study protocol for systematic review and meta-analysis. Medicine (Baltimore). 2022;101(1):e28528. doi:10.1097/MD.0000000000028528.
-
4. Lustyk MKB, Gerrish WG. Premenstrual syndrome and premenstrual dysphoric disorder: ıssues of quality of life, stress and exercise. In: Preedy VR, Watson RR. editors. Handbook of disease burdens and quality of life measures [Internet]. New York, NY: Springer; 2010. p. 1951-75.
-
5. Green R, Dalton K. The premenstrual syndrome. Br Med J. 1953;1(4818):1007-14. doi:10.1136/bmj.1.4818.1007.
-
6. Gül T. Premenstrual syndrome. In: Çiçek MN, Akyürek C, Çelik Ç, Haberal A, editors. Kadın Hastalıkları ve Doğum Bilgisi. Ankara: Güneş Bookstore; 2004. p. 761-5.
-
7. Dennerstein L, Lehert P, Heinemann K. Epidemiology of pre menstrual symptoms and disorders. Menopause Int. 2012; 18(2):48-51. doi:10.1258/mi.2012.012013.
-
8. Borenstein JE, Dean BB, Endicott J, Wong J, Brown C, Dickerson V, et al. Health and economic impact of the premenstrual syndrome. J Reprod Med. 2003;48(7):515-24.
-
9. Epperson CN, Steiner M, Hartlage SA, Eriksson E, Schmidt PJ, Jones I, et al. Premenstrual dysphoric disorder: evidence for a new category for DSM-5. Am J Psychiatry. 2012;169(5):465-75. doi:10.1176/appi.ajp.2012.11081302.
-
10. Direkvand-Moghadam A, Sayehmiri K, Delpisheh A, Satar K. Epidemiology of premenstrual syndrome (PMS)-a systematic review and meta-analysis study. J Clin Diagn Res. 2014;8(2):106-9. doi:10.7860/JCDR/2014/8024.4021.
-
11. Erbil N, Yücesoy H. Premenstrual syndrome prevalence in Turkey: a systematic review and meta-analysis. Psychol Health Med. 2023;28(5):1347-57. doi:10.1080/13548506.2021.2013509.
-
12. Schmidt PJ, Martinez PE, Nieman LK, Koziol DE, Thompson KD, Schenkel L, et al. Premenstrual dysphoric disorder symptoms fol lowing ovarian suppression: triggered by change in ovarian steroid levels but not continuous stable levels. Am J Psychiatry. 2017;174:980-9. doi:10.1176/appi.ajp.2017.16101113.
-
13. Hantsoo L, Epperson CN. Premenstrual dysphoric disorder: epidemiology and treatment. Curr Psychiatry Rep. 2015;17(11):87. doi:10.1007/s11920-015-0628-3.
-
14. Kundakovic M, Rocks D. Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms. Front Neuroendocrinol. 2022;66:101010.
doi:10.1016/j.yfrne.2022.101010.
-
15. Hantsoo L, Epperson CN. Allopregnanolone in premenstrual dysphoric disorder (PMDD): evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle. Neurobiol Stress. 2020;12:100213. doi:10.1016/j.ynstr.2020.100213.
-
16. Bäckström T, Ekberg K, Hirschberg AL, Bixo M, Epperson CN, Briggs P, et al. A randomized, double-blind study on efficacy and safety of sepranolone in premenstrual dysphoric disorder. Psychoneuroendocrinology. 2021;133:105426. doi:10.1016/j.psyneuen.2021.105426.
-
17. Northoff H, Symons S, Zieker D, Schaible EV, Schäfer K, Thoma S, et al. Gender and menstrual phase dependent regulation of inflammatory gene expression in response to aerobic exercise. Exerc Immunol Rev. 2008;14:86-103.
-
18. Gold EB, Wells C, Rasor MO. The Association of Inflammation with Premenstrual Symptoms. J Womens Health (Larchmt). 2016;25(9):865-74. doi:10.1089/jwh.2015.5529.
-
19. Hantsoo L, Payne JL. Towards understanding the biology of premenstrual dysphoric disorder: from genes to GABA. Neurosci Biobehav Rev. 2023;149:105168. doi:10.1016/j.neubiorev.2023.105168.
-
20. Widholm O, Kantero RL. A statistical analysis of the menstrual patterns of 8,000 Finnish girls and their mothers. Acta Obstet Gynecol Scand Suppl. 1971;14:1-36.
-
21. Jahanfar S, Lye MS, Krishnarajah IS. The heritability of premenstrual syndrome. Twin Res Hum Genet. 2011;14(5):433-6. doi:10.1375/twin.14.5.433.
-
22. Menkes DB, Coates DC, Fawcett JP. Acute tryptophan depletion aggravates premenstrual syndrome. J Affective Disord. 1994;32(1):37-44. doi:10.1016/0165-0327(94)90059-0.
-
23. Sadler C, Smith H, Hammond J, Bayly R, Borland S, Panay N, et al. Lifestyle factors, hormonal contraception, and premenstrual symptoms: the United Kingdom Southampton women's survey. J Womens Health. 2010;19(3):391-6. doi:10.1089/jwh.2008.1210.
-
24. Liguori F, Saraiello E, Calella P. Premenstrual syndrome and premenstrual dysphoric disorder's impact on quality of life, and the role of physical activity. Medicina (Kaunas). 2023;59(11):2044. doi:10.3390/medicina59112044.
-
25. Hashim MS, Obaideen AA, Jahrami HA, Radwan H, Hamad HJ, Owais AA, et al. Premenstrual syndrome is associated with dietary and lifestyle behaviors among university students: a cross-sectional study from Sharjah, UAE. Nutrients. 2019;11(8):1939. doi:10.3390/nu11081939.
-
26. Pinar G, Colak M, Oksuz E. Premenstrual syndrome in Turkish college students and its effects on life quality. Sex Reprod Healthc. 2011;2(1):21-7. doi:10.1016/j.srhc.2010.10.001.
-
27. Dilbaz B, Aksan A. Premenstrual syndrome, a common but underrated entity: review of the clinical literature. J Turk Ger Gynecol Assoc. 2021;22(2):139-48. doi:10.4274/jtgga.galenos.2021.2020.0133.
-
28. Freeman EW. Premenstrual syndrome and premenstrual dysphoric disorder: definitions and diagnosis. Psychoneuroendocrinology. 2003;28(3):25-37. doi:10.1016/s0306-4530(03)00099-4.
-
29. Prasad D, Wollenhaupt-Aguiar B, Kidd KN, de Azevedo Cardoso T, Frey BN. Suicidal risk in women with premenstrual syndrome and premenstrual dysphoric disorder: a systematic review and meta-analysis. J Women's Health. 2021;30(12):1693-707. doi:10.1089/jwh.2021.0185.
-
30. Endicott J, Nee J, Harrison W. Daily record of severity of problems (DRSP): reliability and validity. Arch Womens Ment Health. 2006;9(1):41-9. doi:10.1007/s00737-005-0103-y.
-
31. Walsh S, Ismaili E, Naheed B, O'Brien S. Diagnosis, pathophysiology and management of premenstrual syndrome. TOG. 2015;17(2):99-104. doi:10.1111/tog.12180.
-
32. Cary E, Simpson P. Premenstrual disorders and PMDD - a review. Best Pract Res Clin Endocrinol Metab. 2024;38(1):101858. doi:10.1016/j.beem.2023.101858.
-
33. Jarvis CI, Lynch AM, Morin AK. Management strategies for premenstrual syndrome/premenstrual dysphoric disorder. Ann Pharmacother. 2008 Jul;42(7):967-78. doi:10.1345/aph.1K673.
-
34. Hantsoo L, Sajid H, Murphy L, Buchert B, Barone J, Raja S, Eisenlohr-Moul T. Patient experiences of health care providers in premenstrual dysphoric disorder: examining the role of provider specialty. J Womens Health (Larchmt). 2022;31(1):100-9. doi:10.1089/jwh.2020.8797.
-
35. Sayegh R, Schiff I, Wurtman J, Spiers P, McDermott J, Wurtman R. The effect of a carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome. Obstet Gynecol. 1995;86(4):520-8. doi:10.1016/0029-7844(95)00246-n.
-
36. Başoğul C, Aydın Özkan S, Karaca T. The effects of psychoeducation based on the cognitive-behavioural approach on premenstrual syndrome symptoms: a randomised controlled trial. Perspect Psychiatr Care. 2020;56(3):515-22. doi:10.1111/ppc.12460.
-
37. Thys-Jacobs S. Micronutrients and the premenstrual syndrome: the case for calcium. J Am Coll Nutr. 2000;19(2):220-7. doi:10.1080/07315724.2000.10718920.
-
38. Shobeiri F, Araste FE, Ebrahimi R, Jenabi E, Nazari M. Effect of calcium on premenstrual syndrome: a double-blind randomised clinical trial. Obstet Gynecol Sci. 2017;60(1):100-5. doi:10.5468/ogs.2017.60.1.100.
-
39. Retallick-Brown H, Blampied N, Rucklidge JJ. A pilot randomised treatment controlled trial comparing vitamin B6 with broad-spectrum micronutrients for premenstrual syndrome. J Altern Complement Med. 2020;26(2):88-97. doi:10.1089/acm.2019.0305.
-
40. Simsek Kücükkelepce D, Timur Tashan S. The effects of health belief model-based education and acupressure for coping with premenstrual syndrome on premenstrual symptoms and quality of life: a randomised-controlled trial. Perspect Psychiatr Care. 2021;57(1):189-97. doi:10.1111/ppc.12546.
-
41. Kim S, Park H, Lee H, Lee H. Acupuncture for premenstrual syndrome: a systematic review and meta-analysis of randomised controlled trials. BJOG. 2011;118(8):899-915. doi:10.1111/j.1471-0528.2011.02994.x.
-
42. Armour M, Ee CC, Hao J, Wilson TM, Yao SS, Smith CA. Acupuncture and acupressure for premenstrual syndrome. Cochrane Database Syst Rev. 2018;8(8):CD005290. doi:10.1002/14651858.CD005290.pub2.
-
43. Csupor D, Lantos T, Hegyi P, et al. Vitex agnus-castus in premenstrual syndrome: a meta analysis of double-blind randomised controlled trials. Complement Ther Med. 2019;47:102190. doi:10.1016/j.ctim.2019.08.024.
-
44. Ozgoli G, Selselei EA, Mojab F, Majd HA. A randomised, placebo-controlled trial of Ginkgo biloba L. in treatment of premenstrual syndrome. J. Altern. Complement. Med. 2009;15(8):845-51. doi:10.1089/acm.2008.0493.
-
45. Pearce E, Jolly K, Jones L, Matthewman G, Zanganeh M, Daley A. Exercise for premenstrual syndrome: a systematic review and meta-analysis of randomised controlled trials. BJGP Open. 2020;4(3):bjgpopen20X101032. doi:10.3399/bjgpopen20X101032.
-
46. Management of premenstrual syndrome: green-top guideline No. 48. BJOG. 2017;124(3):e73-e105. doi:10.1111/1471-0528.14260.
-
47. Halbreich U, O'Brien PM, Eriksson E, Bäckström T, Yonkers KA, Freeman EW. Are there differential symptom profiles that improve in response to different pharmacological treatments of premenstrual syndrome/premenstrual dysphoric disorder? CNS Drugs. 2006;20(7):523-47. doi:10.2165/00023210-200620070-00001.
-
48. Ismaili E, Walsh S, O'Brien PMS, Bäckström T, Brown C, Dennerstein L, et al. Fourth consensus of the International Society for Premenstrual Disorders (ISPMD): auditable standards for diagnosis and management of premenstrual disorder. Arch Womens Ment Health. 2016;19(6):953-958. doi:10.1007/s00737-016-0631-7.
-
49. Lopez LM, Kaptein AA, Helmerhorst FM. Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database Syst Rev. 2012;(1):CD006586. doi:10.1002/14651858.CD006586.pub2.
-
50. Ma S, Song SJ. Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database Syst Rev. 2023;6(6):CD006586. doi:10.1002/14651858.CD006586.pub5.
Approach to Premenstrual Syndrome and Premenstrual Dysphoric Disorder from the Perspective of Family Medicine
Year 2026,
Volume: 18 Issue: 1, 98 - 103, 24.03.2026
Şeyma Ceylan
,
İsmail Arslan
Abstract
This review aims to present a summary of the current information on the diagnosis, etiology, epidemiology, risk factors, both pharmacological and non-pharmacological treatments in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD), which are common in primary health care and affect women of reproductive age both in terms of quality of life and social aspects.
PMS and PMDD are characterised by physical, behavioural and psychological symptoms that occur during the luteal phase of the menstrual cycle and decrease with menstruation. Both entities affect millions of women at reproductive age as the prevalence of PMS is given as 12-98% while PMDD affects 2-5%. The management of PMS involves a multifaceted approach. Non-pharmacological agents include lifestyle changes, cognitive behavioural therapy, dietary support, education, exercise, calcium and vitamin B6, herbal therapies and acupuncture treatment. Pharmacological treatment options include selective serotonin reuptake inhibitors, combined oral contraceptives and GnRH analogues. The last treatment option is surgery.
In conclusion, defining, diagnosing and managing premenstrual disorders (PMDs) is important both for primary care and other levels of care. Therefore increase in research on PMS and PMDD will raise awareness in the approach of family physicians working in primary health care institutions to patients presenting with premenstrual syndrome and premenstrual dysphoric disorder.
Ethical Statement
This study does not involve human or animal participants. All procedures followed scientific and ethical principles, and all referenced studies are appropriately cited.
Supporting Institution
This research received no external funding.
Thanks
The authors do not wish to acknowledge any individual or institution.
References
-
1. Management of premenstrual disorders: ACOG clinical practice guideline no. 7. Obstet Gynecol. 2023;142(6):1516-33. doi:10.1097/AOG.0000000000005426.
-
2. Modzelewski S, Oracz A, Żukow X, Iłendo K, Śledzikowka Z, Waszkiewicz N. Premenstrual syndrome: new insights into etiology and review of treatment methods. Front Psychiatry. 2024;15:1363875. doi:10.3389/fpsyt.2024.1363875.
-
3. Gao M, Zhang H, Gao Z, Cheng X, Sun Y, Qiao M, et al. Global and regional prevalence and burden for premenstrual syndrome and premenstrual dysphoric disorder: a study protocol for systematic review and meta-analysis. Medicine (Baltimore). 2022;101(1):e28528. doi:10.1097/MD.0000000000028528.
-
4. Lustyk MKB, Gerrish WG. Premenstrual syndrome and premenstrual dysphoric disorder: ıssues of quality of life, stress and exercise. In: Preedy VR, Watson RR. editors. Handbook of disease burdens and quality of life measures [Internet]. New York, NY: Springer; 2010. p. 1951-75.
-
5. Green R, Dalton K. The premenstrual syndrome. Br Med J. 1953;1(4818):1007-14. doi:10.1136/bmj.1.4818.1007.
-
6. Gül T. Premenstrual syndrome. In: Çiçek MN, Akyürek C, Çelik Ç, Haberal A, editors. Kadın Hastalıkları ve Doğum Bilgisi. Ankara: Güneş Bookstore; 2004. p. 761-5.
-
7. Dennerstein L, Lehert P, Heinemann K. Epidemiology of pre menstrual symptoms and disorders. Menopause Int. 2012; 18(2):48-51. doi:10.1258/mi.2012.012013.
-
8. Borenstein JE, Dean BB, Endicott J, Wong J, Brown C, Dickerson V, et al. Health and economic impact of the premenstrual syndrome. J Reprod Med. 2003;48(7):515-24.
-
9. Epperson CN, Steiner M, Hartlage SA, Eriksson E, Schmidt PJ, Jones I, et al. Premenstrual dysphoric disorder: evidence for a new category for DSM-5. Am J Psychiatry. 2012;169(5):465-75. doi:10.1176/appi.ajp.2012.11081302.
-
10. Direkvand-Moghadam A, Sayehmiri K, Delpisheh A, Satar K. Epidemiology of premenstrual syndrome (PMS)-a systematic review and meta-analysis study. J Clin Diagn Res. 2014;8(2):106-9. doi:10.7860/JCDR/2014/8024.4021.
-
11. Erbil N, Yücesoy H. Premenstrual syndrome prevalence in Turkey: a systematic review and meta-analysis. Psychol Health Med. 2023;28(5):1347-57. doi:10.1080/13548506.2021.2013509.
-
12. Schmidt PJ, Martinez PE, Nieman LK, Koziol DE, Thompson KD, Schenkel L, et al. Premenstrual dysphoric disorder symptoms fol lowing ovarian suppression: triggered by change in ovarian steroid levels but not continuous stable levels. Am J Psychiatry. 2017;174:980-9. doi:10.1176/appi.ajp.2017.16101113.
-
13. Hantsoo L, Epperson CN. Premenstrual dysphoric disorder: epidemiology and treatment. Curr Psychiatry Rep. 2015;17(11):87. doi:10.1007/s11920-015-0628-3.
-
14. Kundakovic M, Rocks D. Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms. Front Neuroendocrinol. 2022;66:101010.
doi:10.1016/j.yfrne.2022.101010.
-
15. Hantsoo L, Epperson CN. Allopregnanolone in premenstrual dysphoric disorder (PMDD): evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle. Neurobiol Stress. 2020;12:100213. doi:10.1016/j.ynstr.2020.100213.
-
16. Bäckström T, Ekberg K, Hirschberg AL, Bixo M, Epperson CN, Briggs P, et al. A randomized, double-blind study on efficacy and safety of sepranolone in premenstrual dysphoric disorder. Psychoneuroendocrinology. 2021;133:105426. doi:10.1016/j.psyneuen.2021.105426.
-
17. Northoff H, Symons S, Zieker D, Schaible EV, Schäfer K, Thoma S, et al. Gender and menstrual phase dependent regulation of inflammatory gene expression in response to aerobic exercise. Exerc Immunol Rev. 2008;14:86-103.
-
18. Gold EB, Wells C, Rasor MO. The Association of Inflammation with Premenstrual Symptoms. J Womens Health (Larchmt). 2016;25(9):865-74. doi:10.1089/jwh.2015.5529.
-
19. Hantsoo L, Payne JL. Towards understanding the biology of premenstrual dysphoric disorder: from genes to GABA. Neurosci Biobehav Rev. 2023;149:105168. doi:10.1016/j.neubiorev.2023.105168.
-
20. Widholm O, Kantero RL. A statistical analysis of the menstrual patterns of 8,000 Finnish girls and their mothers. Acta Obstet Gynecol Scand Suppl. 1971;14:1-36.
-
21. Jahanfar S, Lye MS, Krishnarajah IS. The heritability of premenstrual syndrome. Twin Res Hum Genet. 2011;14(5):433-6. doi:10.1375/twin.14.5.433.
-
22. Menkes DB, Coates DC, Fawcett JP. Acute tryptophan depletion aggravates premenstrual syndrome. J Affective Disord. 1994;32(1):37-44. doi:10.1016/0165-0327(94)90059-0.
-
23. Sadler C, Smith H, Hammond J, Bayly R, Borland S, Panay N, et al. Lifestyle factors, hormonal contraception, and premenstrual symptoms: the United Kingdom Southampton women's survey. J Womens Health. 2010;19(3):391-6. doi:10.1089/jwh.2008.1210.
-
24. Liguori F, Saraiello E, Calella P. Premenstrual syndrome and premenstrual dysphoric disorder's impact on quality of life, and the role of physical activity. Medicina (Kaunas). 2023;59(11):2044. doi:10.3390/medicina59112044.
-
25. Hashim MS, Obaideen AA, Jahrami HA, Radwan H, Hamad HJ, Owais AA, et al. Premenstrual syndrome is associated with dietary and lifestyle behaviors among university students: a cross-sectional study from Sharjah, UAE. Nutrients. 2019;11(8):1939. doi:10.3390/nu11081939.
-
26. Pinar G, Colak M, Oksuz E. Premenstrual syndrome in Turkish college students and its effects on life quality. Sex Reprod Healthc. 2011;2(1):21-7. doi:10.1016/j.srhc.2010.10.001.
-
27. Dilbaz B, Aksan A. Premenstrual syndrome, a common but underrated entity: review of the clinical literature. J Turk Ger Gynecol Assoc. 2021;22(2):139-48. doi:10.4274/jtgga.galenos.2021.2020.0133.
-
28. Freeman EW. Premenstrual syndrome and premenstrual dysphoric disorder: definitions and diagnosis. Psychoneuroendocrinology. 2003;28(3):25-37. doi:10.1016/s0306-4530(03)00099-4.
-
29. Prasad D, Wollenhaupt-Aguiar B, Kidd KN, de Azevedo Cardoso T, Frey BN. Suicidal risk in women with premenstrual syndrome and premenstrual dysphoric disorder: a systematic review and meta-analysis. J Women's Health. 2021;30(12):1693-707. doi:10.1089/jwh.2021.0185.
-
30. Endicott J, Nee J, Harrison W. Daily record of severity of problems (DRSP): reliability and validity. Arch Womens Ment Health. 2006;9(1):41-9. doi:10.1007/s00737-005-0103-y.
-
31. Walsh S, Ismaili E, Naheed B, O'Brien S. Diagnosis, pathophysiology and management of premenstrual syndrome. TOG. 2015;17(2):99-104. doi:10.1111/tog.12180.
-
32. Cary E, Simpson P. Premenstrual disorders and PMDD - a review. Best Pract Res Clin Endocrinol Metab. 2024;38(1):101858. doi:10.1016/j.beem.2023.101858.
-
33. Jarvis CI, Lynch AM, Morin AK. Management strategies for premenstrual syndrome/premenstrual dysphoric disorder. Ann Pharmacother. 2008 Jul;42(7):967-78. doi:10.1345/aph.1K673.
-
34. Hantsoo L, Sajid H, Murphy L, Buchert B, Barone J, Raja S, Eisenlohr-Moul T. Patient experiences of health care providers in premenstrual dysphoric disorder: examining the role of provider specialty. J Womens Health (Larchmt). 2022;31(1):100-9. doi:10.1089/jwh.2020.8797.
-
35. Sayegh R, Schiff I, Wurtman J, Spiers P, McDermott J, Wurtman R. The effect of a carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome. Obstet Gynecol. 1995;86(4):520-8. doi:10.1016/0029-7844(95)00246-n.
-
36. Başoğul C, Aydın Özkan S, Karaca T. The effects of psychoeducation based on the cognitive-behavioural approach on premenstrual syndrome symptoms: a randomised controlled trial. Perspect Psychiatr Care. 2020;56(3):515-22. doi:10.1111/ppc.12460.
-
37. Thys-Jacobs S. Micronutrients and the premenstrual syndrome: the case for calcium. J Am Coll Nutr. 2000;19(2):220-7. doi:10.1080/07315724.2000.10718920.
-
38. Shobeiri F, Araste FE, Ebrahimi R, Jenabi E, Nazari M. Effect of calcium on premenstrual syndrome: a double-blind randomised clinical trial. Obstet Gynecol Sci. 2017;60(1):100-5. doi:10.5468/ogs.2017.60.1.100.
-
39. Retallick-Brown H, Blampied N, Rucklidge JJ. A pilot randomised treatment controlled trial comparing vitamin B6 with broad-spectrum micronutrients for premenstrual syndrome. J Altern Complement Med. 2020;26(2):88-97. doi:10.1089/acm.2019.0305.
-
40. Simsek Kücükkelepce D, Timur Tashan S. The effects of health belief model-based education and acupressure for coping with premenstrual syndrome on premenstrual symptoms and quality of life: a randomised-controlled trial. Perspect Psychiatr Care. 2021;57(1):189-97. doi:10.1111/ppc.12546.
-
41. Kim S, Park H, Lee H, Lee H. Acupuncture for premenstrual syndrome: a systematic review and meta-analysis of randomised controlled trials. BJOG. 2011;118(8):899-915. doi:10.1111/j.1471-0528.2011.02994.x.
-
42. Armour M, Ee CC, Hao J, Wilson TM, Yao SS, Smith CA. Acupuncture and acupressure for premenstrual syndrome. Cochrane Database Syst Rev. 2018;8(8):CD005290. doi:10.1002/14651858.CD005290.pub2.
-
43. Csupor D, Lantos T, Hegyi P, et al. Vitex agnus-castus in premenstrual syndrome: a meta analysis of double-blind randomised controlled trials. Complement Ther Med. 2019;47:102190. doi:10.1016/j.ctim.2019.08.024.
-
44. Ozgoli G, Selselei EA, Mojab F, Majd HA. A randomised, placebo-controlled trial of Ginkgo biloba L. in treatment of premenstrual syndrome. J. Altern. Complement. Med. 2009;15(8):845-51. doi:10.1089/acm.2008.0493.
-
45. Pearce E, Jolly K, Jones L, Matthewman G, Zanganeh M, Daley A. Exercise for premenstrual syndrome: a systematic review and meta-analysis of randomised controlled trials. BJGP Open. 2020;4(3):bjgpopen20X101032. doi:10.3399/bjgpopen20X101032.
-
46. Management of premenstrual syndrome: green-top guideline No. 48. BJOG. 2017;124(3):e73-e105. doi:10.1111/1471-0528.14260.
-
47. Halbreich U, O'Brien PM, Eriksson E, Bäckström T, Yonkers KA, Freeman EW. Are there differential symptom profiles that improve in response to different pharmacological treatments of premenstrual syndrome/premenstrual dysphoric disorder? CNS Drugs. 2006;20(7):523-47. doi:10.2165/00023210-200620070-00001.
-
48. Ismaili E, Walsh S, O'Brien PMS, Bäckström T, Brown C, Dennerstein L, et al. Fourth consensus of the International Society for Premenstrual Disorders (ISPMD): auditable standards for diagnosis and management of premenstrual disorder. Arch Womens Ment Health. 2016;19(6):953-958. doi:10.1007/s00737-016-0631-7.
-
49. Lopez LM, Kaptein AA, Helmerhorst FM. Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database Syst Rev. 2012;(1):CD006586. doi:10.1002/14651858.CD006586.pub2.
-
50. Ma S, Song SJ. Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database Syst Rev. 2023;6(6):CD006586. doi:10.1002/14651858.CD006586.pub5.