Research Article

Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series

Volume: 18 Number: 1 March 24, 2026

Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series

Abstract

Aim: Venous insufficiency is a cause of failure in microsurgical replantation and free flap surgery and may be difficult to distinguish intraoperatively from ischemia–reperfusion injury. This study aims to introduce a simple, low-cost, and quantitative intraoperative method—the Hydro-Manometer technique—for assessing venous drainage capacity under physiological pressure conditions.
Material and Methods: This retrospective case series included seven patients treated between 2024 and 2025 who demonstrated clinically relevant venous drainage pathology. The Hydro-Manometer technique was applied intraoperatively in cases showing compromised tissue perfusion despite technically patent arterial and venous anastomoses. Venous drainage capacity was evaluated using a hydrostatic saline column corresponding to physiological venular pressure (20 cmH₂O).
Results: In all cases, arterial and venous anastomoses were confirmed to be patent intraoperatively. Venous thrombosis was identified and treated with thrombectomy in six patients. In one patient, the Hydro-Manometer revealed insufficient venous drainage capacity due to proximal venous pathology, which was successfully managed with venous grafting. All free flaps and replanted tissues survived, with no cases of postoperative venous thrombosis or tissue necrosis during follow-up.
Conclusion: The Hydro-Manometer provides an objective, quantitative, and easily applicable intraoperative assessment of venous drainage capacity in microsurgical procedures. By facilitating differentiation between venous outflow insufficiency and ischemia–reperfusion injury, this method may improve intraoperative decision-making and help prevent avoidable tissue loss.

Keywords

Supporting Institution

This research received no external funding.

Ethical Statement

Institutional ethics committee approval was obtained from Istanbul Medipol University Ethics Comittee prior to data collection. File Date 08/07/2025; File Number: E-10840098-202.3.02-4430

Thanks

The author/authors do not wish to acknowledge any individual or institution.

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Publication Date

March 24, 2026

Submission Date

January 25, 2026

Acceptance Date

March 3, 2026

Published in Issue

Year 2026 Volume: 18 Number: 1

APA
Çetin, O., Kılıç, S., İnce, A. Y., Yılmaz, M. K., & Parmaksızoğlu, F. (2026). Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series. Konuralp Medical Journal, 18(1), 83-87. https://doi.org/10.18521/ktd.1871635
AMA
1.Çetin O, Kılıç S, İnce AY, Yılmaz MK, Parmaksızoğlu F. Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series. Konuralp Medical Journal. 2026;18(1):83-87. doi:10.18521/ktd.1871635
Chicago
Çetin, Onur, Sinan Kılıç, Abdullah Yener İnce, Mehmet Kürşat Yılmaz, and Fatih Parmaksızoğlu. 2026. “Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series”. Konuralp Medical Journal 18 (1): 83-87. https://doi.org/10.18521/ktd.1871635.
EndNote
Çetin O, Kılıç S, İnce AY, Yılmaz MK, Parmaksızoğlu F (March 1, 2026) Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series. Konuralp Medical Journal 18 1 83–87.
IEEE
[1]O. Çetin, S. Kılıç, A. Y. İnce, M. K. Yılmaz, and F. Parmaksızoğlu, “Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series”, Konuralp Medical Journal, vol. 18, no. 1, pp. 83–87, Mar. 2026, doi: 10.18521/ktd.1871635.
ISNAD
Çetin, Onur - Kılıç, Sinan - İnce, Abdullah Yener - Yılmaz, Mehmet Kürşat - Parmaksızoğlu, Fatih. “Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series”. Konuralp Medical Journal 18/1 (March 1, 2026): 83-87. https://doi.org/10.18521/ktd.1871635.
JAMA
1.Çetin O, Kılıç S, İnce AY, Yılmaz MK, Parmaksızoğlu F. Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series. Konuralp Medical Journal. 2026;18:83–87.
MLA
Çetin, Onur, et al. “Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series”. Konuralp Medical Journal, vol. 18, no. 1, Mar. 2026, pp. 83-87, doi:10.18521/ktd.1871635.
Vancouver
1.Onur Çetin, Sinan Kılıç, Abdullah Yener İnce, Mehmet Kürşat Yılmaz, Fatih Parmaksızoğlu. Distinguishing Venous Outflow Insufficiency from Ischemia–Reperfusion Injury Using a Hydro-Manometer: A Case Series. Konuralp Medical Journal. 2026 Mar. 1;18(1):83-7. doi:10.18521/ktd.1871635

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