Vitamin D Levels of Pediatric Intensive Care Patients

Abstract

Objective: By measuring serum 25-hydroxyvitamin D (25-OHVitD) levels of the patients in Pediatric Intensive Care Unit (PICU), vitamin D supplementation is aimed to those who have been determined to have vitamin D deficiency. Furthermore, it is aimed to compare the vitamin D levels of only acute disease patients with acute disease added to the chronic disease in PICU.

Methods: 327 patients (Group A) aged in the range of 1 month to 18 years, that have been hospitalized in PICU of İnönü University TurgutÖzal Medicine Centre from January 2015 to June 2016, and 90 healthy subjects as a control group (Group B) were included. Group A was divided into two; patients with only acute disease (A1=125 patients) and patients with acute disease added to the chronic disease (A2=202 patients). Demographic information and 25-OHVitD, Ca, P, ALP levels of all cases were recorded retrospectively.

Results: Mean of the 25-OHVitD level was 20.9±16.4 ng/dl in Group A; 25.7±17.2 ng/dl in Group A1;17.9±15.2 ng/dl in Group A2 and 25.9±14.4 ng/dl in Group B, respectively. Vitamin D deficiency was 55% in Group A, 43.2% in Group A1, 62.4% in Group A2 and 40% in Group B. In addition, vitamin D insufficiency was 16% in Group A, 17.6% in Group A1, 14.9% in Group A2 and 20% in Group B. On the other hand, vitamin D sufficiency was 29% in Group A, 39.2% in Group A1, 22.8% in Group A2, and 40% in Group B. The increase of age and presence of chronic illness were the determining factors of vitamin D level.

Conclusion: It has been found that, the incidence of vitamin D deficiency increases in prevalence, as age increases. The patients in PICU, especially those who have chronic illness, were found to have vitamin D deficiency more frequent. It is concluded that elimination of vitamin D deficiency may contribute to the treatment of the disease for the patients in PICU and the children with chronic illness.

Keywords

• Vitamin D,pediatric intensive care,Chronic Disease

Çocuk Yoğun Bakım Ünitesindeki Hastaların D Vitamini Seviyeleri

Abstract

Amaç: Çocuk Yoğun Bakım Ünitesinde (ÇYBÜ) yatan hastalarda serum 25-hidroksivitamin D (25-OHVitD) düzeyleri tespit edilerek D vitamini eksikliği saptananlara D vitamini desteği verilmesi; ayrıca ÇYBÜ’deki kronik hastalığı üstüne akut hastalık eklenen hastalarla sadece akut hastalığı olanların D vitamini seviyelerinin karşılaştırılması amaçlandı.

Gereç ve Yöntem: Çalışmaya Ocak 2015- Haziran 2016 tarihleri arasında İnönü Üniversitesi Turgut Özal Tıp Merkezi ÇYBÜ’ye yatırılan 1 ay-18 yaş aralığındaki 327 hasta (A grubu) ve kontrol grubu olarak sağlıklı 90 vaka (B grubu) alındı. A grubu, sadece akut hastalığı olan (A1 grubu=125 hasta) ve kronik hastalığı üzerine akut hastalık eklenen (A2 grubu=202 hasta) hastalar olmak üzere ikiye ayrıldı. Tüm vakaların demografik bilgileri, 25-OHVitD, Ca, P ve ALP düzeyleri retrospektif taranarak kaydedildi.

Bulgular: 25-OHVitD seviye ortalamaları sırasıyla A grubunda 20,9±16,4 ng/dl; A1 grubunda 25,7±17,2 ng/dl; A2 grubunda 17,9±15,2 ng/dl; B grubunda 25,9±14,4 ng/dl bulundu. D vitamini eksikliği sırasıyla A grubunda %55, A1 grubunda %43,2, A2 grubunda %62,4, B grubunda %40; yetersizliği A grubunda %16, A1 grubunda %17,6, A2 grubunda %14,9, B grubunda %20; yeterliliği A grubunda %29, A1 grubunda %39,2, A2 grubunda %22,8, B grubunda %40 bulundu. Yaşın artışı ve kronik hastalık varlığı D vitamini düzeyi üzerinde belirleyici faktörlerdi.

Sonuç: Hastaların yaşı arttıkça D vitamini eksikliği görülme sıklığının arttığı görüldü. ÇYBÜ’deki hastalarda ve özellikle de kronik hastalığı olanlarda D vitamini eksikliğinin daha sık görüldüğü tespit edildi. ÇYBÜ’de yatan ve ek olarak kronik hastalığı olan çocuklarda D vitamini eksikliğinin giderilmesinin tedavilerine katkıda bulunabileceği sonucuna varıldı.

Keywords

• D vitamini,çocuk yoğun bakım,kronik hastalıklar

References

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