The Comparing of the sociodemographic features, anthropometric and biochemical parameters of the cases with Metabolic Syndrome, Type 2 Diabetes Mellitus and healthy controls

Year 2010, Volume: 2 Issue: 1, 12 - 19, 01.04.2010

Demir D

Abstract

Aim: In this study, it was aimed to compare the sociodemographic features and biochemical parameters of the patients with Metabolic Syndrome (MS) and Type 2 Diabetes Mellitus (DM) with control group. Material and Method: In this study, among the patients who applied to Dicle University Faculty of Medicine Family Practice outpatient policlinic, 32 patients with MS, 21 patients with Type 2 DM were taken and 21 patients were selected for control group. Patients with MS and Type 2 DM were compared with control group according to their sociodemographic, anthropometric and biochemical parameters. Results: Of 74 patients applied to the study, 29 were female and 45 were male. There werenít any statistical differences about gender, education, diet and exercise between the three groups (respectively, p=0,224, p=0,216, p=0,234 and p=0,504). W/H ratios, BMI and ages were statistically meaningful between three groups (respectively p=0,001, p=0,005 and p=0,0001). Patients with MS had higher W/H ratios and BMI values. HOMA-IR values were increasing with age (r=0,295, p=0,011), also there was a positive correlation between HOMA-IR and T.CHOL/HDL ratios (r=0.296, p=0.010). Conclusion: While HOMA-IR values were significantly higher in Type 2 DM group, any differences between MS and control group were not detected. Also in both two study groups, HOMA-IR values were increasing with age and there was a positive correlation between HOMA-IR and T.CHOL/HDL ratios. BMI values were positively correlated with systolic and diastolic blood pressures and also W/h ratios. TG values were increasing with W/H ratios.

Keywords

Metabolic Syndrome, Type 2 DM, insulin resistance

Metabolik Sendrom, Tip 2 Diyabetes Mellitus ve Saðl˝kl˝ Bireylerin Sosyodemografik, Antropometrik ve Biyokimyasal ÷zelliklerinin Karº˝laºt˝r˝lmas˝

Abstract

AmaÁ: Bu Áal˝ºmada Metabolik Sendrom (MS) ve Tip 2 Diyabetes Mellitus (DM) hastalar˝n˝n sosyodemografik ˆzellikleri ile biyokimyasal parametrelerinin kontrol grubu ile karº˝laºt˝r˝lmas˝ hedeflenmiºtir. Materyal ve Metot: Dicle ‹niversitesi T˝p Fak¸ltesi Aile Hekimliði polikliniðine yap˝lan baºvurulardan 32 MS, 21 Tip 2 DM tan˝s˝ alm˝º hasta ile 21 kiºi kontrol grubu olarak seÁildi. MS ve Tip 2 DM tan˝s˝ alan hastalar ile kontrol grubu sosyodemografik, antropometrik ve biyokimyasal deðerlerine gˆre karº˝laºt˝r˝ld˝. Bulgular: «al˝ºmaya 29 kad˝n ve 45 erkek olmak ¸zere toplam 74 kiºi al˝nd˝. Kad˝nlar˝n BMI deðeri erkeklerinkinden daha y¸ksekti. Gruplar aras˝nda cinsiyet, eðitim, diyet ve egzersiz aÁ˝s˝ndan fark bulunmamaktayd˝ (s˝ras˝yla p=0.224, p=0.104 p=0.234 ve p=0.504). Gruplar aras˝nda B/K oran˝, BMI ve yaº deðerleri istatistiksel olarak anlaml˝ bulunmuºtur (s˝ras˝yla, p=0.001, p=0.005 ve p<0.0001). MS tan˝s˝ alanlarda B/K oran˝ ve BMI deðerleri daha y¸ksekti. HOMA-IR deðerinde yaºla art˝º saptanm˝º olup (r=0.295, p=0.011), T.KOL/HDL oran˝ ile HOMA-IR aras˝nda da pozitif korelasyon bulunmaktayd˝ (r=0.296, p=0.010). SonuÁ: HOMA-IR deðeri Tip 2 DMíu olanlarda anlaml˝ olarak y¸ksek bulunurken; MS ve kontrol grubu aras˝nda ˆnemli bir farkl˝l˝k saptanmam˝ºt˝r. Her iki Áal˝ºma grubunda da, HOMA-IR deðerinde yaºla art˝º saptanm˝º olup, T.KOL/HDL oran˝ ile HOMA-IR aras˝nda da pozitif korelasyon bulunmaktayd˝. Yine, BMI deðeri ile hem Sistolik TA ñ Diyastolik TA, hem de B/K oran˝ aras˝nda pozitif korelasyon saptand˝. B/K oran˝ art˝kÁa TG deðeri de artmaktayd˝.

Keywords

Metabolik Sendrom, Tip 2 diyabet, insülin direnci

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