Kahramanmaraş Sütçü İmam Üniversitesi Dermatoloji Kliniğinde Kutanöz Leişmanya Tanısı ile Kabul Edilen Hastaların Değerlendirilmesi
Abstract
Leişmanya hücre
içi protozoan parazitlerden kaynaklanan, farklı klinik formlardaki bir hastalık
grubudur. Hastalık, parazitle enfekte olmuş dişi tatarcık sineğinin insandan
kan emerken insana geçmesi ile meydana gelir. Leişmanya türleri Kutanöz,
Mukokutanöz ve visseral formlar olmak üzere 3 esas klinik formu vardır. Klinik
formlar türe ve/veya hastalığın alındığı bölgeye göre değişiklik gösterir. Türkiye’de
visseral ve kutanöz leişmanya formları gözlenir. Bu çalışmanın amacı,
Kahramanmaraş ilinde Kutanöz Leişmanya (KL) durumun incelemek ve bu bölgede
hastalığın önlenmesine katkı sağlamaktır. 2009 yılında 20 KL vakası resmi
olarak bildirilmiştir. 20 vakanın 12’ si bayan 8’i erkek idi. Sürüntü ve
biyopsi sonuçlarına göre 13 vaka pozitif bulundu, biyopsi sonucuna göre 7 vaka
KL negatif olarak değerlendirildi. Hastaların tedavilerinde intralezyonal
meglumum antimonu uygulandı.
References
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- 2. WHO Technical Report Series, 949. Control of the Leishmaniasis report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22-26 March 2010.
- 3. Memişoğlu HR. Kutanöz Leishmaniasis. Ankem Derg 1997; 11 (No.3): 319-2.
- 4. WHO. Expert Committee. Control of the Leishmaniasis. Geneva, 1990.
- 5. WHO. The Leishmaniasis. Control of Tropical Diseases, Geneva, 1993.
- 6. Dos Santos AO: Ueda-Nakamura T, DiasFilho BP, et al. Copaiba Oil: An Alternative to Development of New Drugs against Leishmaniasis. Evid Based Complement Alternat Med. 2012; 2012: 898419.
- 7. Doğan N, Bör O, Dinleyici EC, et al. Investigation of anti-Leishmania seroprevalence by different serologic assays in children inhabiting in then or the westernpart of Turkey. Mikrobiyol Bul 2008; 42 (1): 103-11.
- 8. Corral MJ, González E, Cuquerella M, et al. Improvement of 96-well microplate assay for estimation of cell grow than dinhibition of Leishmania with Alamar Blue. J Microbiol Methods 2013; 94 (2): 111-6.
- 9. TC. Sağlık Bakanlığı Sağlık Araştırmaları Genel Müdürlüğü Sağlık İstatistikleri Yıllığı 2014 verileri, Ankara, 2015.
- 10. Bulaşıcı Hastalıkların Laboratuvar Tanısı için Saha Rehber (Parazitoloji / Mikrobiyolojik Tanımlama / P-MT-05 / Sürüm: 1.1 / 01.01.2015) (Erişim Tarihi: 05.12.2016)
- 11. de Araújo MV, de Souza PS, de Queiroz AC, et al. Synthesis, leishmanicidal activity and theoretical evaluations of a series of substituted bis-2-hydroxy-1,4-naphthoquinones. Molecules 2014;19 (9): 15180-95.
- 12. Barbosa TP, Sousa SC, Amorim FM, et al. Design, synthesis and antileishmanial in vitroactivity of newseries of chalcones-likecompounds: A molecular hybridization approach. Bioorg Med Chem 2011; 19 (14): 4250-6.
- 13. Khalid FA, Nazar M. Abdalla, Husam Eldin O. Et al. Treatment of Cutaneous leishmaniasis with some Local Sudanese Plants (Neem, Garad&Garlic) Turkiye Parazitol Derg 2004; 28 (3): 129-32.
- 14. Bekhit AA, Haimanot T, Hymete A Evaluation of some 1H-pyrazole derivatives as a
- dual acting antimalarial and anti-leishmanial agents. Pak J Pharm Sci 2014; 27 (6):
- 1767-73.
Evaluation of Patients with Cutaneous Leishmaniasis Who Admitted to Dermatology Clinic in Kahramanmaras Sutcu Imam Univercity Medical Faculty
Abstract
Leishmaniasis is a group of diseases, in different
clinical forms, caused by the intracellular protozoan parasites, Leishmania
species. The disease is transmitted by a female sand fly infected with the
parasite sucking blood from people.
Leishmania spp. causes three main clinical forms: cutaneous,
mucocutaneous, and visceral disease. The clinical forms may vary by species
and/or region of acquisition. Two forms are observed in Turkey; visceral
leishmaniasis and cutaneous leishmaniasis. The
aim of this study is to examine the status of Cutaneous Leismaniasis(CL) in the
Kahramanmaras province and contribute to the prevention of the disease in this
region. 20 CL cases were reported officially in 2009. Out of 20 cases, 12 and 8 were female and male. According to smear and biopsy, was found
positive in 13 cases, and negative in 7 cases and the results of biyopsy was
assessment as CL. Intralesional meglumine antimoniate was applied for patients
treatment
References
- 1. Atasoy A, Pasa S, Ozensoy Toz S, et al.. Seroprevalance of canine visceral Leishmaniasis around the Aegean cost of Turkey. Kafkas Univ Vet Fak Derg 2010; 16 (1): 1-6.
- 2. WHO Technical Report Series, 949. Control of the Leishmaniasis report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22-26 March 2010.
- 3. Memişoğlu HR. Kutanöz Leishmaniasis. Ankem Derg 1997; 11 (No.3): 319-2.
- 4. WHO. Expert Committee. Control of the Leishmaniasis. Geneva, 1990.
- 5. WHO. The Leishmaniasis. Control of Tropical Diseases, Geneva, 1993.
- 6. Dos Santos AO: Ueda-Nakamura T, DiasFilho BP, et al. Copaiba Oil: An Alternative to Development of New Drugs against Leishmaniasis. Evid Based Complement Alternat Med. 2012; 2012: 898419.
- 7. Doğan N, Bör O, Dinleyici EC, et al. Investigation of anti-Leishmania seroprevalence by different serologic assays in children inhabiting in then or the westernpart of Turkey. Mikrobiyol Bul 2008; 42 (1): 103-11.
- 8. Corral MJ, González E, Cuquerella M, et al. Improvement of 96-well microplate assay for estimation of cell grow than dinhibition of Leishmania with Alamar Blue. J Microbiol Methods 2013; 94 (2): 111-6.
- 9. TC. Sağlık Bakanlığı Sağlık Araştırmaları Genel Müdürlüğü Sağlık İstatistikleri Yıllığı 2014 verileri, Ankara, 2015.
- 10. Bulaşıcı Hastalıkların Laboratuvar Tanısı için Saha Rehber (Parazitoloji / Mikrobiyolojik Tanımlama / P-MT-05 / Sürüm: 1.1 / 01.01.2015) (Erişim Tarihi: 05.12.2016)
- 11. de Araújo MV, de Souza PS, de Queiroz AC, et al. Synthesis, leishmanicidal activity and theoretical evaluations of a series of substituted bis-2-hydroxy-1,4-naphthoquinones. Molecules 2014;19 (9): 15180-95.
- 12. Barbosa TP, Sousa SC, Amorim FM, et al. Design, synthesis and antileishmanial in vitroactivity of newseries of chalcones-likecompounds: A molecular hybridization approach. Bioorg Med Chem 2011; 19 (14): 4250-6.
- 13. Khalid FA, Nazar M. Abdalla, Husam Eldin O. Et al. Treatment of Cutaneous leishmaniasis with some Local Sudanese Plants (Neem, Garad&Garlic) Turkiye Parazitol Derg 2004; 28 (3): 129-32.
- 14. Bekhit AA, Haimanot T, Hymete A Evaluation of some 1H-pyrazole derivatives as a
- dual acting antimalarial and anti-leishmanial agents. Pak J Pharm Sci 2014; 27 (6):
- 1767-73.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Articles |
| Authors | |
| Publication Date | September 22, 2017 |
| Acceptance Date | August 22, 2017 |
| Published in Issue | Year 2017 Volume: 9 Issue: 3 |