Vitamin D Levels of Pediatric Intensive Care Patients

Year 2018, Volume: 10 Issue: 3, 326 - 332, 23.10.2018

Sait Açık , Mehmet Cengiz Yakıncı

https://doi.org/10.18521/ktd.319492

Cited By: 1

Abstract

Objective: By measuring serum 25-hydroxyvitamin D (25-OHVitD) levels of the patients in Pediatric Intensive Care Unit (PICU), vitamin D supplementation is aimed to those who have been determined to have vitamin D deficiency. Furthermore, it is aimed to compare the vitamin D levels of only acute disease patients with acute disease added to the chronic disease in PICU.

Methods: 327 patients (Group A) aged in the range of 1 month to 18 years, that have been hospitalized in PICU of İnönü University TurgutÖzal Medicine Centre from January 2015 to June 2016, and 90 healthy subjects as a control group (Group B) were included. Group A was divided into two; patients with only acute disease (A1=125 patients) and patients with acute disease added to the chronic disease (A2=202 patients). Demographic information and 25-OHVitD, Ca, P, ALP levels of all cases were recorded retrospectively.

Results: Mean of the 25-OHVitD level was 20.9±16.4 ng/dl in Group A; 25.7±17.2 ng/dl in Group A1;17.9±15.2 ng/dl in Group A2 and 25.9±14.4 ng/dl in Group B, respectively. Vitamin D deficiency was 55% in Group A, 43.2% in Group A1, 62.4% in Group A2 and 40% in Group B. In addition, vitamin D insufficiency was 16% in Group A, 17.6% in Group A1, 14.9% in Group A2 and 20% in Group B. On the other hand, vitamin D sufficiency was 29% in Group A, 39.2% in Group A1, 22.8% in Group A2, and 40% in Group B. The increase of age and presence of chronic illness were the determining factors of vitamin D level.

Conclusion: It has been found that, the incidence of vitamin D deficiency increases in prevalence, as age increases. The patients in PICU, especially those who have chronic illness, were found to have vitamin D deficiency more frequent. It is concluded that elimination of vitamin D deficiency may contribute to the treatment of the disease for the patients in PICU and the children with chronic illness.

Keywords

Vitamin D, pediatric intensive care, Chronic Disease

Çocuk Yoğun Bakım Ünitesindeki Hastaların D Vitamini Seviyeleri

Abstract

Amaç: Çocuk Yoğun Bakım Ünitesinde (ÇYBÜ) yatan hastalarda serum 25-hidroksivitamin D (25-OHVitD) düzeyleri tespit edilerek D vitamini eksikliği saptananlara D vitamini desteği verilmesi; ayrıca ÇYBÜ’deki kronik hastalığı üstüne akut hastalık eklenen hastalarla sadece akut hastalığı olanların D vitamini seviyelerinin karşılaştırılması amaçlandı.

Gereç ve Yöntem: Çalışmaya Ocak 2015- Haziran 2016 tarihleri arasında İnönü Üniversitesi Turgut Özal Tıp Merkezi ÇYBÜ’ye yatırılan 1 ay-18 yaş aralığındaki 327 hasta (A grubu) ve kontrol grubu olarak sağlıklı 90 vaka (B grubu) alındı. A grubu, sadece akut hastalığı olan (A1 grubu=125 hasta) ve kronik hastalığı üzerine akut hastalık eklenen (A2 grubu=202 hasta) hastalar olmak üzere ikiye ayrıldı. Tüm vakaların demografik bilgileri, 25-OHVitD, Ca, P ve ALP düzeyleri retrospektif taranarak kaydedildi.

Bulgular: 25-OHVitD seviye ortalamaları sırasıyla A grubunda 20,9±16,4 ng/dl; A1 grubunda 25,7±17,2 ng/dl; A2 grubunda 17,9±15,2 ng/dl; B grubunda 25,9±14,4 ng/dl bulundu. D vitamini eksikliği sırasıyla A grubunda %55, A1 grubunda %43,2, A2 grubunda %62,4, B grubunda %40; yetersizliği A grubunda %16, A1 grubunda %17,6, A2 grubunda %14,9, B grubunda %20; yeterliliği A grubunda %29, A1 grubunda %39,2, A2 grubunda %22,8, B grubunda %40 bulundu. Yaşın artışı ve kronik hastalık varlığı D vitamini düzeyi üzerinde belirleyici faktörlerdi.

Sonuç: Hastaların yaşı arttıkça D vitamini eksikliği görülme sıklığının arttığı görüldü. ÇYBÜ’deki hastalarda ve özellikle de kronik hastalığı olanlarda D vitamini eksikliğinin daha sık görüldüğü tespit edildi. ÇYBÜ’de yatan ve ek olarak kronik hastalığı olan çocuklarda D vitamini eksikliğinin giderilmesinin tedavilerine katkıda bulunabileceği sonucuna varıldı.

Keywords

D vitamini, çocuk yoğun bakım, kronik hastalıklar

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