Association Between Near Infrared Spectroskopy (NIRS) and Normobaric and Hyperbaric Oxygen Treatment in Acute Carbon Monoxide Poisoning

Year 2019, Volume: 11 Issue: 1, 144 - 149, 25.03.2019

Mücahit Günaydın Ali Aygün Ahmet Ali Top Furkan Yıldırım Hüseyin Alper Vardar

https://doi.org/10.18521/ktd.463325

Abstract

Objective: Carbon monoxide (CO) is the main cause of death and
morbidity associated with poisoning in developed countries. The most important
mortality and morbidity cause of CO poisoning is cerebral hypoxia.
Near-infrared spectroscopy (NIRS) is a useful method for assessing brain
oxygenation. In this study, we aimed to evaluate the brain oxygenation of CO
poisoning patients with NIRS and to investigate its benefits in patients follow
up and treatment.

Materials and
Methods: The study was
conducted as a single-center, prospective clinical trial with 33 patients who
were diagnosed by measuring blood CO-Hb level or referred from other hospitals
diagnosed with CO poisoning. Patients were divided into two groups as
normobaric oxygen therapy (NBOT) group and hyperbaric oxygen therapy (HBOT)
group according to the treatment method applied.

Results: Although average cerebral saturation (ScO2) levels
after treatment were higher in the NBOT group than before treatment, no
statistically significant difference was found except the left frontal ScO2
values. In HBOT group, there was no difference between ScO2 values before and
after treatment sessions.

Conclusion: Our study concluded that NIRS may be useful in
assessing brain oxygenation in CO poisoned patients, but not in determining the
HBOT start-up, and not in monitoring the effectiveness of HBOT.

Keywords

Carbon monoxide poisoning, hyperbaric oxygen therapy, near-infrared spectroscopy, normobaric oxygen theraphy

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