Evaluation of tetanus immunoglobulin G levels according to age and sociodemographic characteristics: A community-based study

Year 2021, Volume: 13 Issue: 3, 488 - 496, 18.10.2021

Ruhuşen Kutlu , Metin Dogan , Ali Rıza Çapa Mahmut Baykan

https://doi.org/10.18521/ktd.765027

Cited By: 1

Abstract

Objective: In the present study, it was aimed to determine the serum tetanus antibody levels in individuals aged 18 and over and examine whether the antibody levels have changed with advancing age.
Methods: This descriptive research was carried out on 916 adults aged 18 years and over in Konya. A survey containing sociodemographic features was filled and tetanus IgG levels was measured.
Results: In this study, 916 suitable people in total who consisted of 68.4% (n=627) female and 31.6% (n=289) male were included. Of the participants, 756 (82.5%) had protective tetanus antibody levels (≥0.1 IU/mL), and 160 (17.5%) had unreliable protective antibody levels (<0.1 IU/mL). No significant difference was found between male and female gender (p=0.225). Antibody levels of those who had secondary and higher education were found significantly higher than those with primary education or less. Antibody levels decrease significantly with increasing age (p<0.001). Antibody levels were significantly found higher the employees than the unemployed (p<0.001), the unmarried than the married (p=0.004), and the people with high income than those with low income (p<0.001) statistically. Antibody levels of those who were vaccinated earlier were found significantly higher (p<0.001).
Conclusions: In this study, it was determined that tetanus antibody levels of the people at old age, with low educational level and without vaccine were lower. Tetanus is a life-threatening public health problem, so new health policies should be developed in this regard.

Keywords

Tetanus antibody,, vaccine,, adult,, seroprevalence

Supporting Institution

This study was supported financially by Necmettin Erbakan University Scientific Research Coordination Center (Number 171218011).

Project Number

Project Number: 171218011

Thanks

The authors thank the Necmettin Erbakan University Scientific Research Coordination Center for the financial support to this study.

Tetanoz immünoglobulin G düzeylerinin yaş ve sosyodemografik özelliklere göre değerlendirilmesi: Toplum temelli bir çalışma

Abstract

Amaç: Sunulan çalışmada serum tetanoz antikor seviyelerinin 18 yaş ve üzeri bireylerde belirlenmesi ve ilerleyen yaş ile birlikte antikor düzeylerinin değişip değişmediğinin incelemesi amaçlanmıştır.
Gereç ve Yöntem: Bu tanımlayıcı araştırma Konya'da 18 yaş ve üstü 916 yetişkin üzerinde yapılmıştır. Sosyodemografik özellikler içeren bir anket dolduruldu ve tetanoz IgG düzeyleri ölçüldü.
Bulgular: Çalışmaya % 68,4 (n = 627) kadın, % 31,6 (n = 289) erkek toplam 916 uygun kişi alındı. Katılımcıların 756'sında (%82,5) koruyucu tetanoz antikor düzeyi (≥0,1 IU / mL) ve 160'ında (%17,5) güvenilir olmayan koruyucu antikor düzeyi (<0,1 IU / mL) vardı. Erkek ve kadın cinsiyet arasında anlamlı bir fark bulunmadı (p=0.225). Ortaokul ve daha üstü eğitimlilerde antikor düzeyleri, ilkokul ve daha az eğitim almış olanlara göre anlamlı olarak yüksek bulunmuştur. Antikor seviyeleri yaş arttıkça önemli ölçüde azalıyordu (p<0,001). Antikor düzeyleri, çalışanlarda işsizlere göre (p<0,001), bekarlarda evli olanlara göre (p=0,004) ve gelir seviyesi yüksek olanlarda düşük geliri olanlara göre (p<0,001) istatistiksel olarak anlamlı derecede yüksek bulundu. Daha önce aşılananların antikor düzeyleri anlamlı olarak yüksekti (p<0,001).
Sonuç: Bu çalışmada, ileri yaşta olanlarda, eğitim düzeyi düşük ve aşılanmamış kişilerde tetanoz antikor düzeylerinin düşük olduğu belirlenmiştir. Tetanoz hayatı tehdit eden bir halk sağlığı sorunudur, bu nedenle bu konuda yeni sağlık politikaları geliştirilmelidir.

Keywords

Tetanoz antikoru, aşı, yetişkin, seroprevalans

Project Number

Project Number: 171218011

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