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Kocaeli İlindeki Alerjik Rinitli Hastaların Deri Prick Testindeki Alerjen Reaktiviteleri

Year 2023, Volume: 9 Issue: 1, 43 - 47, 02.02.2023
https://doi.org/10.30934/kusbed.1177497

Abstract

Amaç: Alerjik rinit (AR)’in tanı ve tedavisinde belirli bir coğrafi bölgedeki AR’yi tetikleyen en yaygın aeroalerjenlerin belirlenmesi önemli bir role sahiptir. Bu çalışma, Kocaeli ilinde yaşayan AR'li hastalarda aeroalerjen duyarlılığının prevalansını değerlendirmektedir.
Yöntem: Bu tek merkezli kesitsel tanımlayıcı çalışma, üçüncü basamak bir hastanenin rinoloji kliniğinde AR öntanısı ile değerlendirilen hastalara ait deri prik testi (DPT) sonuçlarının retrospektif bir incelemesini içermektedir.
Bulgular: AR tanılı 85 hastanın DPT sonuçları analiz edildi. Ev tozu akarları (HDM) en yüksek pozitif test yanıtı sıklığına sahipti (%57.6), bunu ağaç poleni (%40.0), çim poleni (%36.5), yabani ot poleni (%32.9), hamamböceği (%18.8), hayvan tüyü (%14.1) ve küf (%11.8) izledi. Hastaların çoğunluğu polisensitize idi (57.6%) ve bu hastalarda en sık görülen alerjenler sırasıyla ağaç poleni (%61.2), çim poleni (%57.1) ve HDM (%55.1) idi. Monosensitize kişilerde en yaygın tek alerjen %61.1 ile HDM idi.
Sonuç: Kocaeli bölgesinde AR hastaları arasında en sık görülen alerjen HDM'dir, bunu ağaç poleni ve çim polenleri izlemektedir. Polisensitizasyon, monosensitizasyondan daha çok yaygındır. Kocaeli bölgesi hastalarında alerjik rinit tanı ve tedavisinde bu alerjenler öncelikli olarak düşünülmelidir.

References

  • Bousquet J, Anto JM, Bachert C, et al. Allergic rhinitis. Nat Rev Dis Primers. 2020;6(1):95. doi:10.1038/s41572-020-00227-0
  • Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy. 2008;63 Suppl 86:8-160. doi:10.1111/j.1398-9995.2007.01620.x
  • Cingi C, Topuz B, Songu M, et al. Prevalence of allergic rhinitis among the adult population in Turkey. Acta Otolaryngol. 2010;130(5):600-606. doi:10.3109/00016480903311880
  • Dykewicz MS, Fineman S. Executive Summary of Joint Task Force Practice Parameters on Diagnosis and Management of Rhinitis. Ann Allergy Asthma Immunol. 1998;81(5 Pt 2):463-468. doi:10.1016/S1081-1206(10)63152-3
  • Gordon BR. Allergy skin tests and immunotherapy: comparison of methods in common use [published correction appears in Ear Nose Throat J 1990 May;69(5):361]. Ear Nose Throat J. 1990;69(1):47-62.
  • Bousquet PJ, Chinn S, Janson C, et al. Geographical variation in the prevalence of positive skin tests to environmental aeroallergens in the European Community Respiratory Health Survey I. Allergy. 2007;62(3):301-309. doi:10.1111/j.1398-9995.2006.01293.x
  • "Güncel Adrese Dayalı Nüfus Değerleri". Available online at https://biruni.tuik.gov.tr/medas/?kn=95&locale=tr. Archived from the original on December 31, 2021. Accessed September 12, 2022.
  • Migueres M, Dávila I, Frati F, et al. Types of sensitization to aeroallergens: definitions, prevalences and impact on the diagnosis and treatment of allergic respiratory disease. Clin Transl Allergy. 2014;4:16. doi:10.1186/2045-7022-4-16
  • Bousquet J, Annesi-Maesano I, Carat F, et al. Characteristics of intermittent and persistent allergic rhinitis: DREAMS study group. Clin Exp Allergy. 2005;35(6):728-732. doi:10.1111/j.1365-2222.2005.02274.x
  • Mahesh PA, Kummeling I, Amrutha DH, Vedanthan PK. Effect of area of residence on patterns of aeroallergen sensitization in atopic patients. Am J Rhinol Allergy. 2010;24(5):e98-e103. doi:10.2500/ajra.2010.24.3529
  • Valenzano C, Cadario G, Cerè G, Grimaldi I, Oliaro A. Indagine statistica effettuata in Piemonte su 1100 casi di rinite da ipersensibilità ad allergeni inalanti [Statistical study done in Piedmont on 1100 cases of rhinitis caused by hypersensitivity to inhaled allergens]. Minerva Med. 1986;77(3-4):119-122.
  • Turkish State Meteorological Service. Statistical data for cities. Available online at https://www.mgm.gov.tr/veridegerlendirme/il-ve-ilceler-istatistik.aspx?k=A&m=KOCAELI; accessed september 12, 2022.
  • Konuk S. Skin prick test in allergic rhinitis in Duzce province of Turkey. Biomedical Research-Tokyo 2017; (28):6872-6875.
  • Öztürk Ö, Tokmak A, Güçlü E, Yıldızbaş Ş, Gültekin E. Düzce’de Allerjik Rinitli Hastalarda Prick Testi Sonuçları. Duzce Medical Journal. 2005; 7(1): 11-14.
  • Oğuz İD, Hızlı Ö, Akşan B. Giresun Bölgesi Deri Prick Testi Sonuçlarının Kapsamlı Analizi. Konuralp Medical Journal. 2019; 11(2): 295-301.
  • İğde M, İğde F, Sancak R, et al. Orta Karadeniz Bölgesindeki çocuklarda allerji deri testi sonuçları. Turkiye Klinikleri Journal of Pediatrics. 2009;18(2):82-90.
  • Coskun ZO, Erdivanlı OC, Kazıkdas KÇ, et al. High sensitization to house-dust mites in patients with allergic rhinitis in the eastern Black Sea region of Turkey: A retrospective study. Am J Rhinol Allergy. 2016;30(5):351-355. doi:10.2500/ajra.2016.30.4353
  • Aydin S, Hardal U, Atli H. An analysis of skin prick test reactions in allergic rhinitis patients in Istanbul, Turkey. Asian Pac J Allergy Immunol. 2009;27(1):19-25.
  • D'Amato G, Cecchi L, Bonini S, et al. Allergenic pollen and pollen allergy in Europe. Allergy. 2007;62(9):976-990. doi:10.1111/j.1398-9995.2007.01393.x

Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey

Year 2023, Volume: 9 Issue: 1, 43 - 47, 02.02.2023
https://doi.org/10.30934/kusbed.1177497

Abstract

Objective: The identification of the most common aeroallergens causing allergic rhinitis (AR) in a specific geographic area is important in the diagnosis and treatment of AR. This study evaluates the prevalence of sensitivity to aeroallergens among patients with AR who live in Kocaeli province, Turkey.
Methods: This cross-sectional, descriptive study included a retrospective review of skin prick test (SPT) results from patients with suspected AR who were examined at a tertiary hospital rhinology clinic.
Results: The SPT results of 85 patients with an AR diagnosis were included in this study. House dust mites (HDM) had the highest frequency of positive test responses (57.6%), followed by tree pollen (40.0%), grass pollen (36.5%), weed pollen (32.9%), cockroach (18.8%), animal dander (14.1%), and mold (11.8%). The majority of the AR patients were polysensitized (57.6%), and the most common allergens in polysensitized patients were tree pollen (61.2%), grass pollen (57.1%), and HDM (55.1%), respectively. The strongest single allergen in monosensitized subjects was HDM, with a rate of 61.1%.
Conclusion: The most prevalent allergen was HDM among AR patients in the Kocaeli region, followed by tree pollen and grass pollen. Polisensitization occurs more frequently than monosensitization. These allergens should be prioritized in the diagnosis and treatment of allergic rhinitis in Kocaeli region patients.

References

  • Bousquet J, Anto JM, Bachert C, et al. Allergic rhinitis. Nat Rev Dis Primers. 2020;6(1):95. doi:10.1038/s41572-020-00227-0
  • Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy. 2008;63 Suppl 86:8-160. doi:10.1111/j.1398-9995.2007.01620.x
  • Cingi C, Topuz B, Songu M, et al. Prevalence of allergic rhinitis among the adult population in Turkey. Acta Otolaryngol. 2010;130(5):600-606. doi:10.3109/00016480903311880
  • Dykewicz MS, Fineman S. Executive Summary of Joint Task Force Practice Parameters on Diagnosis and Management of Rhinitis. Ann Allergy Asthma Immunol. 1998;81(5 Pt 2):463-468. doi:10.1016/S1081-1206(10)63152-3
  • Gordon BR. Allergy skin tests and immunotherapy: comparison of methods in common use [published correction appears in Ear Nose Throat J 1990 May;69(5):361]. Ear Nose Throat J. 1990;69(1):47-62.
  • Bousquet PJ, Chinn S, Janson C, et al. Geographical variation in the prevalence of positive skin tests to environmental aeroallergens in the European Community Respiratory Health Survey I. Allergy. 2007;62(3):301-309. doi:10.1111/j.1398-9995.2006.01293.x
  • "Güncel Adrese Dayalı Nüfus Değerleri". Available online at https://biruni.tuik.gov.tr/medas/?kn=95&locale=tr. Archived from the original on December 31, 2021. Accessed September 12, 2022.
  • Migueres M, Dávila I, Frati F, et al. Types of sensitization to aeroallergens: definitions, prevalences and impact on the diagnosis and treatment of allergic respiratory disease. Clin Transl Allergy. 2014;4:16. doi:10.1186/2045-7022-4-16
  • Bousquet J, Annesi-Maesano I, Carat F, et al. Characteristics of intermittent and persistent allergic rhinitis: DREAMS study group. Clin Exp Allergy. 2005;35(6):728-732. doi:10.1111/j.1365-2222.2005.02274.x
  • Mahesh PA, Kummeling I, Amrutha DH, Vedanthan PK. Effect of area of residence on patterns of aeroallergen sensitization in atopic patients. Am J Rhinol Allergy. 2010;24(5):e98-e103. doi:10.2500/ajra.2010.24.3529
  • Valenzano C, Cadario G, Cerè G, Grimaldi I, Oliaro A. Indagine statistica effettuata in Piemonte su 1100 casi di rinite da ipersensibilità ad allergeni inalanti [Statistical study done in Piedmont on 1100 cases of rhinitis caused by hypersensitivity to inhaled allergens]. Minerva Med. 1986;77(3-4):119-122.
  • Turkish State Meteorological Service. Statistical data for cities. Available online at https://www.mgm.gov.tr/veridegerlendirme/il-ve-ilceler-istatistik.aspx?k=A&m=KOCAELI; accessed september 12, 2022.
  • Konuk S. Skin prick test in allergic rhinitis in Duzce province of Turkey. Biomedical Research-Tokyo 2017; (28):6872-6875.
  • Öztürk Ö, Tokmak A, Güçlü E, Yıldızbaş Ş, Gültekin E. Düzce’de Allerjik Rinitli Hastalarda Prick Testi Sonuçları. Duzce Medical Journal. 2005; 7(1): 11-14.
  • Oğuz İD, Hızlı Ö, Akşan B. Giresun Bölgesi Deri Prick Testi Sonuçlarının Kapsamlı Analizi. Konuralp Medical Journal. 2019; 11(2): 295-301.
  • İğde M, İğde F, Sancak R, et al. Orta Karadeniz Bölgesindeki çocuklarda allerji deri testi sonuçları. Turkiye Klinikleri Journal of Pediatrics. 2009;18(2):82-90.
  • Coskun ZO, Erdivanlı OC, Kazıkdas KÇ, et al. High sensitization to house-dust mites in patients with allergic rhinitis in the eastern Black Sea region of Turkey: A retrospective study. Am J Rhinol Allergy. 2016;30(5):351-355. doi:10.2500/ajra.2016.30.4353
  • Aydin S, Hardal U, Atli H. An analysis of skin prick test reactions in allergic rhinitis patients in Istanbul, Turkey. Asian Pac J Allergy Immunol. 2009;27(1):19-25.
  • D'Amato G, Cecchi L, Bonini S, et al. Allergenic pollen and pollen allergy in Europe. Allergy. 2007;62(9):976-990. doi:10.1111/j.1398-9995.2007.01393.x
There are 19 citations in total.

Details

Primary Language English
Subjects Allergy
Journal Section Original Article / Medical Sciences
Authors

Atılay Yaylacı 0000-0002-7842-0342

Publication Date February 2, 2023
Submission Date September 20, 2022
Acceptance Date December 26, 2022
Published in Issue Year 2023 Volume: 9 Issue: 1

Cite

APA Yaylacı, A. (2023). Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi, 9(1), 43-47. https://doi.org/10.30934/kusbed.1177497
AMA Yaylacı A. Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey. KOU Sag Bil Derg. February 2023;9(1):43-47. doi:10.30934/kusbed.1177497
Chicago Yaylacı, Atılay. “Skin Prick Test Reactivity to Common Allergens Among Allergic Rhinitis Patients in Kocaeli Province, Turkey”. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi 9, no. 1 (February 2023): 43-47. https://doi.org/10.30934/kusbed.1177497.
EndNote Yaylacı A (February 1, 2023) Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi 9 1 43–47.
IEEE A. Yaylacı, “Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey”, KOU Sag Bil Derg, vol. 9, no. 1, pp. 43–47, 2023, doi: 10.30934/kusbed.1177497.
ISNAD Yaylacı, Atılay. “Skin Prick Test Reactivity to Common Allergens Among Allergic Rhinitis Patients in Kocaeli Province, Turkey”. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi 9/1 (February 2023), 43-47. https://doi.org/10.30934/kusbed.1177497.
JAMA Yaylacı A. Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey. KOU Sag Bil Derg. 2023;9:43–47.
MLA Yaylacı, Atılay. “Skin Prick Test Reactivity to Common Allergens Among Allergic Rhinitis Patients in Kocaeli Province, Turkey”. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi, vol. 9, no. 1, 2023, pp. 43-47, doi:10.30934/kusbed.1177497.
Vancouver Yaylacı A. Skin Prick Test Reactivity to Common Allergens among Allergic Rhinitis Patients in Kocaeli Province, Turkey. KOU Sag Bil Derg. 2023;9(1):43-7.