Case Report
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A CASE OF OZENA IN A REFUGEE CAMP MIGRANT

Year 2026, Volume: 28 Issue: 1 , 153 - 156 , 27.04.2026
https://doi.org/10.24938/kutfd.1681784
https://izlik.org/JA23JB26ZU

Abstract

Ozena is a type of primary atrophic rhinitis caused by the bacterium Klebsiella pneumoniae ssp. ozaenae. A 45-year-old female patient who had migrated from Syria to Türkiye presented with complaints of foul-smelling rhinorrhea and persistent nasal crusting for several years. On examination, abundant yellow-green crusts, enlarged nasal cavities, and atrophic turbinates and mucosa were observed in both nasal passages. Klebsiella pneumoniae ssp. ozaenae was isolated in the nasal tissue culture. The patient was hospitalized and treated with ceftriaxone and metronidazole for two weeks, as these antibiotics were found to be effective based on culture results. Nasal irrigation with physiological saline and glycerin-based moisturizer was recommended. Additionally, daily nasal crust removal was performed using an endoscope. After discharge, the patient was prescribed ceftriaxone 1 g IM twice daily for two weeks. Regular follow-ups were recommended for the recovering patient.We present this case because the condition is relatively unknown and often diagnosed late.

References

  • Maalej F, Chaabouni MA, Ayadi S, Sellami M, Charfeddine I. Therapeutic management of primary atrophic rhinitis (Ozene): About 4 cases. Ear Nose Throat J. 2024;14:1455613241252586.
  • Flint PW, Haughey BH, Lund VJ, et al. Nonallergic rhinitis. Cummings Otolaryngology, 5th edition. Elsevier, 2010:696–697.
  • Yelenich-Huss MJ, Boyer H, Alpern JD, Stauffer WM, Schmidt D. Ozena in immigrants of differing backgrounds. Am J Trop Med Hyg. 2016;95(1):35-37.
  • Awad OGAN, Hasan MM. Topical Mitomycin-C can help as an adjunct to alkaline nasal wash and rifampicin in primary atrophic rhinitis. Am J Otolaryngol. 2019;40(2):137-142.
  • Yuca SA, Yuca K, Kiroglu AF, et al. A forgotten difficult entity: ozena report of 2 cases . E J Med. 2010;15:114–117.
  • Dutt SN, Kameswaran M. The aetiology and management of atrophic rhinitis. J Laryngol Otol. 2005;119(11):843-852.
  • Chhabra N, Houser SM. The diagnosis and management of empty nose syndrome. Otolaryngol Clin North Am. 2009;42(2):311-330
  • Tomooka LT, Murphy C, Davidson TM. Clinical study and literature review of nasal irrigation. Laryngoscope. 2000;110(7):1189-1193.
  • Brown AC, Slocum PC, Putthoff SL, Wallace WE, Foresman BH. Exogenous lipoid pneumonia due to nasal application of petroleum jelly. Chest. 1994;105(3):968-969.
  • Sumaily IA, Hakami NA, Almutairi AD, et al. An Updated review on atrophic rhinitis and empty nose syndrome. Ear Nose Throat J. 2023;1455613231185022.
  • AlJindan R. Epidemiological characteristics of Klebsiella ozaenae infection and its antibiotic susceptibility: Experience of a tertiary care hospital in the Eastern Province of Saudi Arabia. J Family Community Med. 2024;31(2):148-152.

Mülteci Kampında Yaşayan Bir Göçmende Ozaena Olgusu

Year 2026, Volume: 28 Issue: 1 , 153 - 156 , 27.04.2026
https://doi.org/10.24938/kutfd.1681784
https://izlik.org/JA23JB26ZU

Abstract

Ozaena, Klebsiella pneumoniae’nın ozaenae alttürü bakterisinin neden olduğu bir tür primer atrofik rinittir. Suriye'den Türkiye'ye göç eden 45 yaşında bir kadın hasta, birkaç yıldır kötü kokulu burun akıntısı ve kalıcı burun kabuğu şikayetiyle başvurdu. Muayenede, her iki burun pasajında bol miktarda sarı-yeşil kabuklar, genişlemiş burun boşlukları, atrofik konkalar ve mukoza görüldü. Burun doku kültüründe Klebsiella pneumoniae’nın ozaenae alttürü izole edildi. Hasta hastaneye yatırıldı ve kültür sonuçlarına göre bu antibiyotiklerin etkili olduğu görüldüğünden iki hafta boyunca seftriakson ve metronidazol ile tedavi edildi. Fizyolojik tuzlu su ve gliserin bazlı nemlendirici ile burun irrigasyonu önerildi. Ayrıca, bir endoskop kullanılarak günlük burun kabuğu temizliği yapıldı. Taburcu olduktan sonra hastaya iki hafta boyunca günde iki kez 1 g IM seftriakson reçete edildi. İyileşen hastaya düzenli takipler önerildi. Bu vakayı sunuyoruz çünkü durum nispeten bilinmiyor ve genellikle geç teşhis ediliyor.

References

  • Maalej F, Chaabouni MA, Ayadi S, Sellami M, Charfeddine I. Therapeutic management of primary atrophic rhinitis (Ozene): About 4 cases. Ear Nose Throat J. 2024;14:1455613241252586.
  • Flint PW, Haughey BH, Lund VJ, et al. Nonallergic rhinitis. Cummings Otolaryngology, 5th edition. Elsevier, 2010:696–697.
  • Yelenich-Huss MJ, Boyer H, Alpern JD, Stauffer WM, Schmidt D. Ozena in immigrants of differing backgrounds. Am J Trop Med Hyg. 2016;95(1):35-37.
  • Awad OGAN, Hasan MM. Topical Mitomycin-C can help as an adjunct to alkaline nasal wash and rifampicin in primary atrophic rhinitis. Am J Otolaryngol. 2019;40(2):137-142.
  • Yuca SA, Yuca K, Kiroglu AF, et al. A forgotten difficult entity: ozena report of 2 cases . E J Med. 2010;15:114–117.
  • Dutt SN, Kameswaran M. The aetiology and management of atrophic rhinitis. J Laryngol Otol. 2005;119(11):843-852.
  • Chhabra N, Houser SM. The diagnosis and management of empty nose syndrome. Otolaryngol Clin North Am. 2009;42(2):311-330
  • Tomooka LT, Murphy C, Davidson TM. Clinical study and literature review of nasal irrigation. Laryngoscope. 2000;110(7):1189-1193.
  • Brown AC, Slocum PC, Putthoff SL, Wallace WE, Foresman BH. Exogenous lipoid pneumonia due to nasal application of petroleum jelly. Chest. 1994;105(3):968-969.
  • Sumaily IA, Hakami NA, Almutairi AD, et al. An Updated review on atrophic rhinitis and empty nose syndrome. Ear Nose Throat J. 2023;1455613231185022.
  • AlJindan R. Epidemiological characteristics of Klebsiella ozaenae infection and its antibiotic susceptibility: Experience of a tertiary care hospital in the Eastern Province of Saudi Arabia. J Family Community Med. 2024;31(2):148-152.
There are 11 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Süheyla Kandemir 0000-0003-3354-2212

Büşra Keleş 0009-0009-9998-7573

Submission Date April 22, 2025
Acceptance Date November 17, 2025
Publication Date April 27, 2026
DOI https://doi.org/10.24938/kutfd.1681784
IZ https://izlik.org/JA23JB26ZU
Published in Issue Year 2026 Volume: 28 Issue: 1

Cite

APA Kandemir, S., & Keleş, B. (2026). A CASE OF OZENA IN A REFUGEE CAMP MIGRANT. The Journal of Kırıkkale University Faculty of Medicine, 28(1), 153-156. https://doi.org/10.24938/kutfd.1681784
AMA 1.Kandemir S, Keleş B. A CASE OF OZENA IN A REFUGEE CAMP MIGRANT. Kırıkkale Uni Med J. 2026;28(1):153-156. doi:10.24938/kutfd.1681784
Chicago Kandemir, Süheyla, and Büşra Keleş. 2026. “A CASE OF OZENA IN A REFUGEE CAMP MIGRANT”. The Journal of Kırıkkale University Faculty of Medicine 28 (1): 153-56. https://doi.org/10.24938/kutfd.1681784.
EndNote Kandemir S, Keleş B (April 1, 2026) A CASE OF OZENA IN A REFUGEE CAMP MIGRANT. The Journal of Kırıkkale University Faculty of Medicine 28 1 153–156.
IEEE [1]S. Kandemir and B. Keleş, “A CASE OF OZENA IN A REFUGEE CAMP MIGRANT”, Kırıkkale Uni Med J, vol. 28, no. 1, pp. 153–156, Apr. 2026, doi: 10.24938/kutfd.1681784.
ISNAD Kandemir, Süheyla - Keleş, Büşra. “A CASE OF OZENA IN A REFUGEE CAMP MIGRANT”. The Journal of Kırıkkale University Faculty of Medicine 28/1 (April 1, 2026): 153-156. https://doi.org/10.24938/kutfd.1681784.
JAMA 1.Kandemir S, Keleş B. A CASE OF OZENA IN A REFUGEE CAMP MIGRANT. Kırıkkale Uni Med J. 2026;28:153–156.
MLA Kandemir, Süheyla, and Büşra Keleş. “A CASE OF OZENA IN A REFUGEE CAMP MIGRANT”. The Journal of Kırıkkale University Faculty of Medicine, vol. 28, no. 1, Apr. 2026, pp. 153-6, doi:10.24938/kutfd.1681784.
Vancouver 1.Süheyla Kandemir, Büşra Keleş. A CASE OF OZENA IN A REFUGEE CAMP MIGRANT. Kırıkkale Uni Med J. 2026 Apr. 1;28(1):153-6. doi:10.24938/kutfd.1681784

This Journal is a Publication of Kırıkkale University Faculty of Medicine.