THE ANALYSIS OF CARBON MONOXIDE POISONING CASES PRESENTED TO THE EMERGENCY DEPARTMENT OF A UNIVERSITY HOSPITAL

Year 2016, , 123 - 126, 15.12.2016

Abuzer Coşkun Afşin Emre Kayıpmaz Sedat Özbay Osman Mahir Okur Şevki Hakan Eren Cemil Kavalcı

https://doi.org/10.24938/kutfd.277970

Abstract

Introduction: Carbon monoxide poisoning is one of
the most leading poisoning causing death through worldwide, although its exact
incidence is yet to be determined. Carbon monoxide is a colorless and odorless
gas that binds to hemoglobin and cellular oxidative enzymes with a higher
affinity than oxygen, causing tissue hypoxia. Hypoxia of heart and nervous
system cells leads to neuropsychiatric and cardiological signs and symptoms.  In
this study, we aimed to investigate the demographic characteristics of the
carbon monoxide poisonings occurring in patients presenting to the emergency
department. We also aimed to determine the clinical characteristics, and the
factors affecting the mortality.

Material and Methods: We retrospectively reviewed the
demographic and clinical characteristics of 1013 patients who admitted to our
adult emergency department and were diagnosed with carbon monoxide poisoning
for a period of two years. We recorded and analyzed age, gender, season of
presentation, hospital admission rate, sources of poisoning, symptoms at
admission, mortality rate, and carboxyhemoglobin and cardiac Troponin-I levels.

Results: The mean age of the study population
was 36.2±16.2 years. 70.5% of the patients were admitted in winter seasons.
66.1% of the patients’ poisoning source was water
heater and stove. The most frequent symptoms were nausea, headache, and
dizziness. On multilogistic regression analysis the death rate was
significantly correlated with age and cardiac Troponin I level.

Conclusion: Our
results indicate that accidental carbon monoxide poisonings continue to be an
important public health problem in regions with cold winter seasons. We believe
that intensifying efforts for public education and efficient control of
resources of poisoning are the key steps to prevent carbon monoxide poisonings.

Keywords

Epidemiology, carbon-monoxide, poisoning

BİR ÜNİVERSİTE HASTANESİ ACİL SERVİSİNE BAŞVURAN KARBON MONOKSİT ZEHİRLENMESİ OLGULARININ ANALİZİ

Abstract

Giriş: Karbonmonoksit zehirlenmesi,
insidansı kesin olarak bilinmemekle birlikte dünya çapında ölüme sebep olan
başlıca zehirlenmelerden birisidir. Karbonmonoksit, hemoglobine ve hücresel
oksidatif enzimlere oksijenden daha yüksek bir afiniteyle bağlanarak doku
hipoksisine neden olan renksiz ve kokusuz bir gazdır. Kalp ve sinir sistemi
hücrelerindeki hipoksi, nöropsikiyatrik ve kardiyolojik belirti ve bulgularının
oluşmasına yol açar. Bu çalışmada karbonmonoksit zehirlenmesi nedeniyle acil
servise başvuran olguların demografik ve klinik özelliklerini araştırmayı
amaçladık.

Gereç ve Yöntem: Erişkin acil servisimize iki yıllık
bir süre zarfında başvurup karbonmonoksit zehirlenmesi tanısı alan 1013
hastanın demografik ve klinik özelliklerini retrospektif olarak gözden
geçirdik. Hastaların yaş, cinsiyet, başvuru mevsimi, hastane yatış oranı,
zehirlenmenin kaynağı, başvuru belirtileri, mortalite oranı, karboksihemoglobin
ve Troponin I seviyeleriyle ilgili bilgileri kayıt ve analiz ettik.

Bulgular: Çalışma popülâsyonunun ortalama yaşı
36.2±16.2’di. Hastaların %70,5’i kış mevsiminde başvuru yapmıştı. Hastaların
%66,1’inin zehirlenme kaynağı sıcak su ısıtıcısı, gazla çalışan sobalardı. En
sık bulgular bulantı, baş ağrısı ve sersemlik hissiydi. Multilojistik regresyon
analizinde ölüm hızı ile yaş ve kardiyak Troponin I düzeyi arasında anlamlı
ilişki olduğu tespit edildi.

Sonuç: Çalışmamızın sonuçları,
karbonmonoksit zehirlenmesinin zorlu kış koşullarının hâkim olduğu bölgelerde
halen önemli bir halk sağlığı problemi olduğunu ortaya koymaktadır. Toplumun
eğitimi ve zehirlenme kaynaklarının ile karbonmonoksit zehirlenmesinin
önlenebilir olacağını düşünmekteyiz.  

Keywords

Epidemiyoloji, karbonmonoksit, zehirlenme

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