GENÇ YAŞTA SAPTANMIŞ SPORADİK KOLON KANSERİ: OLGU SUNUMU

Abstract

Kolon adenokarsinomu 30 yaş altında ender rastlanılan bir hastalıktır. Özellikle pediatrik yaş grubunda geç fark edilmesinden dolayı hastalık ilerleyerek prezente olmaktadır. Kolorektal kanserler çocuklarda ve adolesanlarda, erişkinlere göre daha kötü prognoza sahiptir. Tanı anında genç hastalarda yaşlı hastalara göre daha ileri evrede karşımıza çıkarlar. Bu olgu sunumunda, altı aylık süreçte kilo kaybı, ateş, bağırsak alışkanlıklarında değişiklik, karın ağrısı şikayetleri bulunan ve tüberküloz, lenfoma ön tanısıyla tetkik edilen, kolonoskopik biyopsi sonucu müsinöz adenokarsinom tanısı alan, 19 yaşında ve bilinen risk faktörü olmayan bir erkek hastanın Bilgisayarlı Tomografi (BT) ve Manyetik Rezonans Görüntüleme (MRG) bulgularını literatür bilgileri eşliğinde sunmayı amaçladık. Klinik bulguları olan genç hastaların radyolojik değerlendirilmesinde dikkatli olunmalı ve kolon kanseri akılda tutulmalıdır.

Keywords

• Kolorektal kanser,genç hasta,radyolojik bulgular,erken tanı

Sporadic Colon Cancer in a Young Adult: A Case Report

Abstract

Colon adenocarcinoma is rarely seen in patients under age of 30 and it is presented as advanced disease and diagnosed in the late stages especially in pediatric age groups. Colorectal cancers have a worse prognosis in children and adolescents compared to adults. Younger patients are diagnosed at an advanced stage compared to adult patients. A 19-year old male patient who was being investigated for the prediagnosis of tuberculosis and lymphoma for complaints of weight loss, fever, alteration in bowel functions, abdominal pain during six months period is presented in this report. The male patient had no known risk factors for colon cancer and colonoscopic biopsy result revealed mucinous adenocarcinoma. We aimed to present the findings of magnetic resonance imaging and computed tomography with review of the literature. Caution should be exercised in the radiological evaluation of young patients with clinical findings and colon cancer should be kept in mind.

Keywords

• Colorectal cancer,young patients,radiologic findings,early diagnosis

References

1. 1- Shih HH, et al. Adenocarcinoma of the Colon in Children Presenting as Abdominal Pain: Report of Two Cases. Chang Gung Med J. 2002;25:349-54
2. 2- Kravarusic D, et al. Colorectal carcinoma in childhood: a retrospective multicenter study. Journal of Pediatric Gastroenterology and Nutrition. vol. 44, no. 2, pp. 209–211, 2007.
3. 3- Chantada GL, et al. Colorectal carcinoma in children, adolescents, and young adults. Journal of Pediatric Hematology/Oncology. vol. 27, no.1, pp. 39–41, 2005.
4. 4- Hill DA, et al. Colorectal carcinoma in childhood and adolescence: a clinicopathologic review. Journal of Clinical Oncology. vol. 25, no. 36, pp. 5808–5814, 2007.
5. 5- Angelini C, et al. Colorectal cancer with neuroendocrine differentiation in a child. Pediatric Surgery International. vol. 21, no. 10, pp. 839–840, 2005.
6. 6- Chan KK, et al. Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and longterm: Analysis of survival and prognostic markers. World Journal of Surgical Oncology 2010, 8:82
7. 7- O’Connell JB, et al. Colorectal cancer in the young. Am J Surg. 2004;187:343-348.
8. 8- Andersson A, Bergdahl L. Carcinoma of the colon in children: a report of six cases and a review of the literature. J Pediatr Surg. 1976;11:967-71.

9. 9- Gupta SK, Caballes RL. Adenocarcinoma of colon in a child. J Pediatr Gastroenterol Nutr 1986;5:973-6.
10. 10- Culter SJ. Proceedings: report on the Third National Cancer Survey. Proc Natl Cancer Conf 1973;7:639-52.
11. 11- Dozois EJ, et al. Young-onset colorectal cancer in patients with no known genetic predisposition: can we increase early recognition and improve outcome?. Medicine (Baltimore) 2008;87:259-263.
12. 12- Chiang JM, et al. Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. Int J Colorectal Dis. 2010;25:941-947.
13. 13- Muccillo A, et al. Colon Mucinous Adenocarcinoma in Childhood :A Case Report with Emphasis on Image Findings. Case Reports in Medicine. 2010, Article ID 327634, 3 pages
14. 14- Griffin PM, et al. Adenocarcinomas of the colon and rectum in persons under 40 years old. A population-based study. Gastroenterology 1991;100:1033-1040
15. 15- Horton KM, Abrams RA, Fishman EK .Spiral CT of Colon Cancer: Imaging Features and Role in Management. RadioGraphics 2000; 20:419–430