Spontaneous Ejaculation without Orgasm after Micturition Induced by Venlafaxine and Paroxetine: A Case Report

Year 2018, , 349 - 352, 30.12.2018

Mehmet Hamdi Örüm , Mahmut Zabit Kara , Oğuzhan Bekir Eğilmez

https://doi.org/10.24938/kutfd.435991

Cited By: 1

Abstract

Spontaneous ejaculation after micturition is a rare side
effect of antidepressants. Serotonin noradrenaline reuptake inhibitors (SNRIs)
and selective serotonin reuptake inhibitors (SSRIs) are reported to cause
spontaneous ejaculation. Venlafaxine is a SNRI, paroxetine is a SSRI. Nausea,
constipation, appetite and sleep changes are some side effects associated with
the use of venlafaxine and paroxetine. We report the case of a man who had
spontaneous ejaculations after using venlafaxine. Spontaneous ejaculations
continued after the switching to paroxetine. The side effect ceased after
discontinuation of paroxetine and did not appear with sertraline. This unusual
side effect should be questioned in patients who receive venlafaxine and
paroxetine, as it may cause embarrassment and noncompliance.

Keywords

Sexual dysfunction, ejaculation, paroxetine, sertraline, venlafaxine

VENLAFAKSİN VE PAROKSETİN KULLANIMINA BAĞLI, ORGAZM OLMAKSIZIN İDRAR SONRASINDA ORTAYA ÇIKAN SPONTAN EJAKÜLASYONLAR: BİR OLGU SUNUMU

Abstract

Miksiyonu takiben ortaya çıkan spontan ejakülasyon,
antidepresanların nadir görülen bir yan etkisidir. Serotonin noradrenalin geri
alım inhibitörleri (SNGİ) ve seçici serotonin geri alım inhibitörleri
(SSGİ)’nin spontan ejakülasyona neden olduğu bildirilmiştir. Venlafaksin bir
SNGİ, paroksetin ise bir SSGİ’dir. Mide bulantısı, kabızlık, iştah ve uyku
değişiklikleri venlafaksin ve paroksetin kullanımı ile ilgili bazı yan
etkilerdir. Biz bu olgu sunumunda, venlafaksin başlanan erkek hastada ortaya
çıkan spontan ejakülasyonu ele aldık. Spontan ejakülasyonlar venlafaksin
kesilip, paroksetine geçildikten sonra devam etti. Sadece sertralin
kullanılması sırasında yan etki bildirilmedi. Sık görülmeyen bu yan etki,
venlafaksin ve paroksetin alan hastalarda sorgulanmalıdır. Aksi takdirde bu yan
etki hastalarda utanma ve uyumsuzluğa neden olabilmektedir.

Keywords

Cinsel işlev bozukluğu, ejakülasyon, paroksetin, sertraline, venlafaksin

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