Spontaneous Ejaculation without Orgasm after Micturition Induced by Venlafaxine and Paroxetine: A Case Report

Abstract

Spontaneous ejaculation after micturition is a rare side effect of antidepressants. Serotonin noradrenaline reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs) are reported to cause spontaneous ejaculation. Venlafaxine is a SNRI, paroxetine is a SSRI. Nausea, constipation, appetite and sleep changes are some side effects associated with the use of venlafaxine and paroxetine. We report the case of a man who had spontaneous ejaculations after using venlafaxine. Spontaneous ejaculations continued after the switching to paroxetine. The side effect ceased after discontinuation of paroxetine and did not appear with sertraline. This unusual side effect should be questioned in patients who receive venlafaxine and paroxetine, as it may cause embarrassment and noncompliance.

Keywords

• Sexual dysfunction,ejaculation,paroxetine,sertraline,venlafaxine

VENLAFAKSİN VE PAROKSETİN KULLANIMINA BAĞLI, ORGAZM OLMAKSIZIN İDRAR SONRASINDA ORTAYA ÇIKAN SPONTAN EJAKÜLASYONLAR: BİR OLGU SUNUMU

Abstract

Miksiyonu takiben ortaya çıkan spontan ejakülasyon, antidepresanların nadir görülen bir yan etkisidir. Serotonin noradrenalin geri alım inhibitörleri (SNGİ) ve seçici serotonin geri alım inhibitörleri (SSGİ)’nin spontan ejakülasyona neden olduğu bildirilmiştir. Venlafaksin bir SNGİ, paroksetin ise bir SSGİ’dir. Mide bulantısı, kabızlık, iştah ve uyku değişiklikleri venlafaksin ve paroksetin kullanımı ile ilgili bazı yan etkilerdir. Biz bu olgu sunumunda, venlafaksin başlanan erkek hastada ortaya çıkan spontan ejakülasyonu ele aldık. Spontan ejakülasyonlar venlafaksin kesilip, paroksetine geçildikten sonra devam etti. Sadece sertralin kullanılması sırasında yan etki bildirilmedi. Sık görülmeyen bu yan etki, venlafaksin ve paroksetin alan hastalarda sorgulanmalıdır. Aksi takdirde bu yan etki hastalarda utanma ve uyumsuzluğa neden olabilmektedir.

Keywords

• Cinsel işlev bozukluğu,ejakülasyon,paroksetin,sertraline,venlafaksin

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