Tokolitik Tedavide Güncel Yaklaşımlar

Year 2015, Volume: 17 Issue: 2, 27 - 35, 05.01.2016

Osman Köse

https://doi.org/10.24938/kutfd.124919

Abstract

Uzun yıllardır kullanılmakta olan tokolitik ajanların, son literatür bilgileri ile etkinliği ve yan etkilerinin değerlendirilerek; ilk tercih edilmesi gereken tokolitik ajanın belirlemeyi amaçladık. Erken doğum eylemi tanısı ile izlenen hastalarda uygulanan tıbbi tedavilerden ß agonistler, Ca kanal blokerleri ve atosibana göre daha fazla yan etkiye neden olmakta, atosiban ise yan etkisi daha az ve ruhsatlı olmasına rağmen daha pahalı olması dezavantajını taşımaktadır. Nifedipin için hala ruhsatlı olmaması doz çalışmalarının yapılmamış olması dezavantajları olarak görülmektedir. Sonuç olarak ilk tercih edilmesi gereken tokolitik tedavi henüz belirlenememiş olup geniş kapsamlı randomize çalışmalara ihtiyaç duyulmaktadır.

Keywords

Tokoliz, Ca kanal blokerleri, ß agonistler, MgSO4

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