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Epididymo-Orchitis in Children: A Review of 35 Cases

Year 2018, Volume: 20 Issue: 1, 62 - 67, 30.04.2018
https://doi.org/10.24938/kutfd.349886

Abstract

ObjectiveEpididymo-orchitis
is extremely rare in infants and children. The pathophysiologic mechanisms for
the development of Epididymo-orchitis are not well known in most of cases. This
retrospective review was undertaken to determine causes, management and long
term follow-up of this pathology.

Material and Methods: During a 13 years period (between January 1993 and December
2006), a total 35 children with Epididymo-orchitis were enrolled in this study.
Mean age of patients was 10.5 ± 3.7 (range: 1-14 years). Diagnosis of
epididymo-orchitis was made by patients’ history, physical examination and
scrotal Doppler ultrasonographic examination of testes. Urinary system
sonography, urinalysis, urine culture and in cases of doubt intravenous
urography were performed to detect the underlying abnormalities.

Results: The causes for Epididymo-orchitis were as follows: idiopathic
Epididymo-orchitis (n=22), mumps epididymo-orchitis (n=9), bacterial
epididymo-orchitis (n=1), tuberculous epididymo-orchitis (n=1) and
epididymo-orchitis resulting from Henoch-Schönlein purpura (n=2). In patient
with tuberculosis Epididymo-orchitis, no evidence of tuberculosis infection in
his urine. This case received aproppriate combination chemotherapy and
underwent orchiectomy. Of 35 cases 15 were followed up for long term periods.
Mean follow-up time was 49.0 ± 35.8 months (range: 13 months-13 years). Mean
volume of testis was significantly lower in testes with Epididymo-orchitis
compared to those of contralateral ones (p <0.01).

Conclusion: Differentiating
the causes of acute scrotum can sometimes be difficult if only the clinical
features or laboratory data are employed. Doppler ultrasound examination is the
most useful method in differential diagnosis especially for torsion of the
spermatic cord. 

References

  • Hagley M. Epididymo-orchitis and epididymitis: a review of causes and management of unusual forms. Int J STD AIDS. 2003;14(6):372-7.
  • Gislason T, Noronha RF, Gregory JG. Acute epididymitis in boys: a 5-year retrospective study. J Urol. 1980;124(4):533-4.
  • Liu CC, Huang SP, Chou YH, Li CC, Wu MT, Huang CH, et al. Clinical presentation of acute scrotum in young males. Kaohsiung J Med Sci. 2007;23(6):281-5.
  • Kadish HA, Bolte RG. A retrospective review of pediatric patients with epididymitis, testicular torsion, and torsion of testicular appendages. Pediatrics. 1998;102:73-6.
  • Siegel A, Snyder H, Duckett JW. Epididymitis in infants and boys: underlying urogenital anomalies and efficacy of imaging modalities J Urol. 1987;138:1100-3.
  • Philip J, Selvan D, Desmond AD. Mumps orchitis in the non-immune postpubertal male: a resurgent threat to male fertility? BJU Int. 2006;97(1):138-41.
  • Lane TM, Hines J. The management of mumps orchitis. BJU Int. 2006;97(1):1-2.
  • Ku JH, Kim YH, Jeon YS, Lee NK. The preventive effect of systemic treatment with interferon-alpha2B for infertility from mumps orchitis. BJU Int. 1999;84:839-42.
  • Yeniyol CO, Sorguc S, Minareci S, Ayder AR. Role of interferon-alpha-2B in prevention of testicular atrophy with unilateral mumps orchitis. Urology. 2000;55:931-3.
  • Lewis AG, Bukowski TP, Jarvis PD, Wacksman J, Sheldon CA. Evaluation of acute scrotum in the emergency department. J Pediatr Surg. 1995;30:277-81.
  • Mufti RA, Ogedegbe AK, Lafferty K. The use of Doppler ultrasound in the clinical management of acute testicular pain Br J Urol. 1995;76:625-7.
  • Watkin NA, Reiger NA, Moisey CU. Is the conservative management of the acute scrotum justified on clinical grounds? Br J Urol. 1996;78:623-7.
  • Ingram S, Hollman AS, Azmy A. Testicular torsion: missed diagnosis on colour Doppler sonography. Pediatr Radiol. 1993;23:483-4.
  • Allen TD, Elder JS. Shortcomings of color Doppler sonography in the diagnosis of testicular torsion. J Urol. 1995;154:1508-10.

ÇOCUKLARDA EPİDİDİMO-ORŞİTLER: 35 OLGUNUN GÖZDEN GEÇİRİLMESİ

Year 2018, Volume: 20 Issue: 1, 62 - 67, 30.04.2018
https://doi.org/10.24938/kutfd.349886

Abstract

Amaç: Epididimo-orşit infant ve
çocuklarda son derece nadir görülen bir patolojidir. Çoğu olguda epididimo-orşit gelişimindeki patofizyolojik mekanizma
anlaşılamamıştır. Bu retrospektif çalışmada bu patolojinin olası nedenleri,
tanı ve tedavisiyle uzun dönem takip sonuçlarını irdelemeyi amaçladık.

Gereç ve Yöntem: Ocak 1993 ile Aralık 2006 tarihleri
arasındaki 13 yıllık periyotat epididimo-orşit tanısı almış 35 olgu bu
çalışmaya kapsamına alındı. Hastaların yaş ortalaması 10.5 ± 3.7 yıl (1-14 yıl)
idi. Epididimo-orşit tanısı, öykü, fizik muayene ve skrotal doppler
ultrasonografi ile konuldu. Altta yatan patolojiyi ortaya koyabilmek için
üriner sistem ultrasonografisi, idrar tetkiki, idrar kültürü ve şüpheli
olgularda intravenöz ürografi yaptırıldı.

Bulgular: Epididimo-orşit’in nedenleri şu şekilde idi: idiopatik
Epididimo-orşit (n = 22), kabakulak Epididimo-orşit (n=9), bakteriyel
epididimo-orşit (n=1), tüberküloz epididimo-orşit (n=1) ve Henoch-Schönlein
purpurasına bağlı oluşmuş epididimo-orşit (n=2). Tüberküloz epididimo-orşit’i
olan hastanın idrarında tüberküloz enfeksiyonunu gösteren bir bulgu yoktu. Bu
olgu, uygun antitüberküloz ilaç tedavisi ve
orşiektomi ile tedavi edildi. Otuz beş olgunun 15’inde uzun dönem takip
yapılabildi. Ortalama takip süresi 49.0 ± 35.8 ay (13 ay-13 yıl) idi. Ortalama
testis volümleri karşı sağlam testisle karşılaştırıldığında epididimo-orşit
tarafında anlamlı derecede düşük bulundu (p <0.01).

Sonuç: Akut
skrotumun nedenlerinin ayırıcı tanısında sadece klinik özellikler ve
laboratuvar verileri kullanıldığında zorlanılmaktadır. Doppler ultrasonografi
ayırıcı tanıda, özellikle de spermatik kord torsiyonunun ayırımında en
kullanışlı metottur.

References

  • Hagley M. Epididymo-orchitis and epididymitis: a review of causes and management of unusual forms. Int J STD AIDS. 2003;14(6):372-7.
  • Gislason T, Noronha RF, Gregory JG. Acute epididymitis in boys: a 5-year retrospective study. J Urol. 1980;124(4):533-4.
  • Liu CC, Huang SP, Chou YH, Li CC, Wu MT, Huang CH, et al. Clinical presentation of acute scrotum in young males. Kaohsiung J Med Sci. 2007;23(6):281-5.
  • Kadish HA, Bolte RG. A retrospective review of pediatric patients with epididymitis, testicular torsion, and torsion of testicular appendages. Pediatrics. 1998;102:73-6.
  • Siegel A, Snyder H, Duckett JW. Epididymitis in infants and boys: underlying urogenital anomalies and efficacy of imaging modalities J Urol. 1987;138:1100-3.
  • Philip J, Selvan D, Desmond AD. Mumps orchitis in the non-immune postpubertal male: a resurgent threat to male fertility? BJU Int. 2006;97(1):138-41.
  • Lane TM, Hines J. The management of mumps orchitis. BJU Int. 2006;97(1):1-2.
  • Ku JH, Kim YH, Jeon YS, Lee NK. The preventive effect of systemic treatment with interferon-alpha2B for infertility from mumps orchitis. BJU Int. 1999;84:839-42.
  • Yeniyol CO, Sorguc S, Minareci S, Ayder AR. Role of interferon-alpha-2B in prevention of testicular atrophy with unilateral mumps orchitis. Urology. 2000;55:931-3.
  • Lewis AG, Bukowski TP, Jarvis PD, Wacksman J, Sheldon CA. Evaluation of acute scrotum in the emergency department. J Pediatr Surg. 1995;30:277-81.
  • Mufti RA, Ogedegbe AK, Lafferty K. The use of Doppler ultrasound in the clinical management of acute testicular pain Br J Urol. 1995;76:625-7.
  • Watkin NA, Reiger NA, Moisey CU. Is the conservative management of the acute scrotum justified on clinical grounds? Br J Urol. 1996;78:623-7.
  • Ingram S, Hollman AS, Azmy A. Testicular torsion: missed diagnosis on colour Doppler sonography. Pediatr Radiol. 1993;23:483-4.
  • Allen TD, Elder JS. Shortcomings of color Doppler sonography in the diagnosis of testicular torsion. J Urol. 1995;154:1508-10.
There are 14 citations in total.

Details

Subjects Health Care Administration
Journal Section Articles
Authors

Hasan Rıza Aydın

Azam Demirel

Publication Date April 30, 2018
Submission Date November 7, 2017
Published in Issue Year 2018 Volume: 20 Issue: 1

Cite

APA Aydın, H. R., & Demirel, A. (2018). Epididymo-Orchitis in Children: A Review of 35 Cases. The Journal of Kırıkkale University Faculty of Medicine, 20(1), 62-67. https://doi.org/10.24938/kutfd.349886
AMA Aydın HR, Demirel A. Epididymo-Orchitis in Children: A Review of 35 Cases. Kırıkkale Uni Med J. April 2018;20(1):62-67. doi:10.24938/kutfd.349886
Chicago Aydın, Hasan Rıza, and Azam Demirel. “Epididymo-Orchitis in Children: A Review of 35 Cases”. The Journal of Kırıkkale University Faculty of Medicine 20, no. 1 (April 2018): 62-67. https://doi.org/10.24938/kutfd.349886.
EndNote Aydın HR, Demirel A (April 1, 2018) Epididymo-Orchitis in Children: A Review of 35 Cases. The Journal of Kırıkkale University Faculty of Medicine 20 1 62–67.
IEEE H. R. Aydın and A. Demirel, “Epididymo-Orchitis in Children: A Review of 35 Cases”, Kırıkkale Uni Med J, vol. 20, no. 1, pp. 62–67, 2018, doi: 10.24938/kutfd.349886.
ISNAD Aydın, Hasan Rıza - Demirel, Azam. “Epididymo-Orchitis in Children: A Review of 35 Cases”. The Journal of Kırıkkale University Faculty of Medicine 20/1 (April 2018), 62-67. https://doi.org/10.24938/kutfd.349886.
JAMA Aydın HR, Demirel A. Epididymo-Orchitis in Children: A Review of 35 Cases. Kırıkkale Uni Med J. 2018;20:62–67.
MLA Aydın, Hasan Rıza and Azam Demirel. “Epididymo-Orchitis in Children: A Review of 35 Cases”. The Journal of Kırıkkale University Faculty of Medicine, vol. 20, no. 1, 2018, pp. 62-67, doi:10.24938/kutfd.349886.
Vancouver Aydın HR, Demirel A. Epididymo-Orchitis in Children: A Review of 35 Cases. Kırıkkale Uni Med J. 2018;20(1):62-7.

This Journal is a Publication of Kırıkkale University Faculty of Medicine.