HYPERCALCEMIA DUE TO PRIMARY HYPERPARATHYROIDISM IN A PATIENT WITH GRAVES' DISEASE

Year 2022, Volume: 24 Issue: 1, 192 - 196, 30.04.2022

Işılay Kalan Sarı Ramazan Coşar Şenay Arıkan Durmaz

https://doi.org/10.24938/kutfd.857414

Abstract

Hyperthyroidism is a hypermetabolic condition associated with excessive production of thyroid hormones by the thyroid gland. Thyroid hormones play an important role in bone and calcium metabolism. Mild to moderate hypercalcemia due to hyperthyroidism has been reported in approximately one in five patients. Hypercalcemia due to hyperthyroidism is associated with decreased or subnormal parathyroid hormone levels. The co-occurrence of hyperthyroidism and primary hyperparathyroidism is rare. However, in patients with hyperthyroidism, it is necessary to evaluate the parathyroid glands if hypercalcemia persists after an euthyroid state is reached.

Here, we report the case of a 30-year-old man with hypercalcemia who had Graves' disease and primary hyperparathyroidism and was successfully treated with combined thyroid and parathyroid surgery.

Keywords

hyperthyroidism, hyperparathyroidism, hypercalcemia, Graves

Bir Graves Hastasında Primer Hiperparatiroidiye Bağlı Hiperkalsemi

Abstract

Hipertiroidizm, tiroid bezi tarafından aşırı tiroid hormonu üretimi ile olan ilişkili hipermetabolik bir durumdur. Tiroid hormonlarının kemik ve kalsiyum metabolizması üzerine önemli etkileri vardır. Yaklaşık beş hastadan birinde hipertiroidiye bağlı hafif ila orta derecede hiperkalsemi bildirilmiştir. Hipertiroidiye sekonder hiperkalsemiye azalmış ya da subnormal parathormon seviyeleri eşlik eder. Hipertiroidizm ile hiperparatiroidizm birlikteliği nadir olarak görülmektedir. Bununla birlikte, hipertiroidi hastalarında ötiroid duruma ulaştıktan sonra hiperkalseminin devam etmesi durumunda paratiroid bezlerinin ayrıntılı olarak değerlendirilmesi gerekir.

Burada, hiperkalsemisi olan, Graves hastalığı ve primer hiperparatiroidizm tanısı alan, kombine tiroid ve paratiroid cerrahisi ile başarılı bir şekilde tedavi edilen 30 yaşında bir erkek hasta olgusunu sunuyoruz.

Keywords

Hipertiroidizm, hiperparatiroidizm, hiperkalsemi, Graves hastalığı

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