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EVALUATION OF THE EYELID AND PERIOCULAR TUMORS

Year 2022, Volume: 24 Issue: 2, 357 - 364, 31.08.2022
https://doi.org/10.24938/kutfd.1096679

Abstract

Objective: Our aim was to determine and compare the demographic and histopathological features of eyelid and periocular tumors.
Material and Methods: The medical records of the patients who had eyelid and periocular tumor surgery were retrospectively analyzed at the ophthalmology clinic. The data included age, gender, tumor location and histopathological outcomes and comparative study was performed between the benign, malignant and premalignant tumors. Detailed site of the tumor was described as right and left or bilateral, upper and lower. Medial and lateral canthal tumors and eyebrow tumors were described as periocular tumors. SPSS computer statistical software (version Chicago) was used for statistical analysis. Chi-square test was used for the significant differences.
Results: A total of 190 patients with histopathologic confirmation were evaluated; 160 were (84.2%) eyelid lesions and 30 (15.8%) were periocular lesions. One hundred and forty (87.5%) of the eyelid lesions were benign, 17 (10.6%) of eyelid lesions were malignant and 3 (1.8%) of lesions were premalignant. Twenty (66.7%) of the periocular lesions were benign, 9 (30%) malignant and 1 (3.3%) was premalignant. Benign tumors were found to occur at younger ages compared to malignant (p=0.03) and premalignant lesions (p=0.038). One hundred and ten (68.7%) of benign tumors were seen in women and 50 (31.3%) in men. In contrast to benign tumors, malignant and premalignant tumors were more common in males (p=0.003). Malignant tumors were found to be significantly higher in the right eyes. There was a statistically significant difference in malignancy between periocular and eyelid tumors (χ(2)=8.488, p=0.014). Malignant tumors were found to be significantly higher in periocular lesions. Epidermal cyst (17.5%) was the most common benign tumor. Basal cell carcinoma was the most frequent malignant type (73.1%).
Conclusion: Gender of male, lower lid location and senility are the risk factors that should be concerned in eyelid and periocular tumors.

References

  • 1. Deprez M, Uffer S. Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature. Am J Dermatopathol. 2009;31(3):256-62.
  • 2. Welch RB, Duke JR. Lesions of the lids; a statistical note. Am J Ophthalmol. 1958;45(3):415-26.
  • 3. Aurora AL, Blodi FC. Lesions of the eyelids: clinicopathological study. Surv Ophthalmol. 1970;15:94-104.
  • 4. Tesluk GC. Eyelid lesions: incidence and comparison of benign and malignant lesions. Ann Ophthalmol. 1985;17(11):704-7.
  • 5. Margo CE. Eyelid tumors: accuracy of clinical diagnosis. Am J Ophthalmol. 1999;128(5):635-6.
  • 6. Sendul SY, Akpolat C, Yilmaz Z, Eryilmaz OT, Guven D, Kabukcuoglu F. Clinical and pathological diagnosis and comparison of benign and malignant eyelid tumors. J Fr Ophtalmol. 2021;44(4):537-43.
  • 7. Yumuşak ME, Onaran Z, Örnek K, Oğurel T, Balcı M. Göz kapağı ve perioküler bölge tümörlerinin histopatolojik dağılımı. Ortadoğu Tıp Dergisi. 2016;8(3):135-39.
  • 8. Xu XL, Li B, Sun XL, Li LQ, Ren RJ, Gao F et al. Eyelid neoplasms in the Beijing Tongren Eye Centre between 1997 and 2006. Ophthalmic Surg Lasers Imaging. 2008;39(5):367-72.
  • 9. Huang YY, Liang WY, Tsai CC, Kao SC, Yu WK, Kau HC et al. Comparison of the clinical characteristics and outcome of benign and malignant eyelid tumors: an analysis of 4521 eyelid tumors in a tertiary medical center. Biomed Res Int. 2015;2015:453091.
  • 10. Gundogan FC, Yolcu U, Tas A, Sahin OF, Uzun S, Cermik H et al. Eyelid tumors: clinical data from an eye center in Ankara, Turkey. Asian Pac J Cancer Prev. 2015;16(10):4265-9.
  • 11. Asproudis I, Sotiropoulos G, Gartzios C, Raggos V, Papoudou-Bai A, Ntountas I et al. Eyelid tumors at the University Eye Clinic of Ioannina, Greece: A 30-year retrospective study. Middle East Afr J Ophthalmol. 2015;22(2):230-2.
  • 12. Yu SS, Zhao Y, Zhao H, Lin JY, Tang X. A retrospective study of 2228 cases with eyelid tumors. Int J Ophthalmol. 2018;11(11):1835-41.
  • 13. Kaliki S, Bothra N, Bejjanki KM, Nayak A, Ramappa G, Mohamed A et al. Malignant eyelid tumors in India: A Study of 536 Asian Indian Patients. Ocul Oncol Pathol. 2019;5(3):210-9.
  • 14. De Potter P, Disneur D, Levecq L, Snyers B. Ocular manifestations of cancer. J Fr Ophtalmol. 2002;25(2):194-202.
  • 15. Burgic M, Iljazovic E, Vodencarevic AN, Burgic M, Rifatbegovic A, Mujkanovic A et al. Clinical characteristics and outcome of malignant eyelid tumors: A five-year retrospective study. Med Arch. 2019;73(3):209-12.

Göz Kapağı ve Perioküler Tümörlerin Değerlendirilmesi

Year 2022, Volume: 24 Issue: 2, 357 - 364, 31.08.2022
https://doi.org/10.24938/kutfd.1096679

Abstract

Amaç: Amacımız göz kapağı ve perioküler tümörlerin demografik ve histopatolojik özelliklerini belirlemek ve karşılaştırmaktır.
Gereç ve Yöntemler: Göz hastalıkları kliniğinde göz kapağı ve perioküler tümör cerrahisi geçiren hastaların tıbbi kayıtları retrospektif olarak incelendi. Veriler yaş, cinsiyet, tümör yerleşimi ve histopatolojik sonuçları içeriyordu ve benign, malign ve premalign tümörler arasında karşılaştırmalı çalışma yapıldı. Tümörün ayrıntılı bölgesi sağ ve sol veya iki taraflı, üst ve alt olarak tanımlandı. Medial ve lateral kantal tümörler ve kaş tümörleri perioküler tümörler olarak tanımlandı. İstatistiksel analiz için SPSS bilgisayar istatistik yazılımı (versiyon Chicago) kullanıldı. Anlamlı farklılıklar için ki-kare testi kullanıldı.
Bulgular: Histopatolojik doğrulaması yapılan toplam 190 hasta değerlendirildi, 160'ı (%84.2) göz kapağı lezyonu ve 30'u (%15.8) perioküler lezyondu. Göz kapağı lezyonlarının 140'ı (%87.5) benign, 17'si (%10.6) malign ve 3'ü (%1.8) premalign idi. Perioküler lezyonların 20'si (%66.7) benign, 9'u (%30) malign ve 1'i (%3.3) premalign idi. Benign tümörlerin malign (p=0.03) ve premalign lezyonlara (p=0.038) göre daha genç yaşlarda ortaya çıktığı bulundu. Benign tümörlerin 110’u (%68.7) kadınlarda 50’si (%31.3) erkeklerde görüldü. Benign tümörlerin aksine malign ve premalign tümörler erkeklerde daha sıktı (p=0.003). Sağ gözde malign tümörler anlamlı derecede yüksek bulundu. Perioküler ve göz kapağı tümörleri arasında malignite açısından istatistiksel olarak anlamlı bir fark vardı (χ(2)=8.488, p=0.014). Malign tümörler perioküler lezyonlarda anlamlı olarak daha yüksek bulundu. Epidermal kist (%17.5) en sık görülen benign tümördü. Bazal hücreli karsinom en sık görülen malign tipti (%73.1).
Sonuç: Erkek cinsiyeti, alt kapak yerleşimi ve yaşlılık, göz kapağı ve perioküler tümörlerde dikkat edilmesi gereken risk faktörleridir.

References

  • 1. Deprez M, Uffer S. Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature. Am J Dermatopathol. 2009;31(3):256-62.
  • 2. Welch RB, Duke JR. Lesions of the lids; a statistical note. Am J Ophthalmol. 1958;45(3):415-26.
  • 3. Aurora AL, Blodi FC. Lesions of the eyelids: clinicopathological study. Surv Ophthalmol. 1970;15:94-104.
  • 4. Tesluk GC. Eyelid lesions: incidence and comparison of benign and malignant lesions. Ann Ophthalmol. 1985;17(11):704-7.
  • 5. Margo CE. Eyelid tumors: accuracy of clinical diagnosis. Am J Ophthalmol. 1999;128(5):635-6.
  • 6. Sendul SY, Akpolat C, Yilmaz Z, Eryilmaz OT, Guven D, Kabukcuoglu F. Clinical and pathological diagnosis and comparison of benign and malignant eyelid tumors. J Fr Ophtalmol. 2021;44(4):537-43.
  • 7. Yumuşak ME, Onaran Z, Örnek K, Oğurel T, Balcı M. Göz kapağı ve perioküler bölge tümörlerinin histopatolojik dağılımı. Ortadoğu Tıp Dergisi. 2016;8(3):135-39.
  • 8. Xu XL, Li B, Sun XL, Li LQ, Ren RJ, Gao F et al. Eyelid neoplasms in the Beijing Tongren Eye Centre between 1997 and 2006. Ophthalmic Surg Lasers Imaging. 2008;39(5):367-72.
  • 9. Huang YY, Liang WY, Tsai CC, Kao SC, Yu WK, Kau HC et al. Comparison of the clinical characteristics and outcome of benign and malignant eyelid tumors: an analysis of 4521 eyelid tumors in a tertiary medical center. Biomed Res Int. 2015;2015:453091.
  • 10. Gundogan FC, Yolcu U, Tas A, Sahin OF, Uzun S, Cermik H et al. Eyelid tumors: clinical data from an eye center in Ankara, Turkey. Asian Pac J Cancer Prev. 2015;16(10):4265-9.
  • 11. Asproudis I, Sotiropoulos G, Gartzios C, Raggos V, Papoudou-Bai A, Ntountas I et al. Eyelid tumors at the University Eye Clinic of Ioannina, Greece: A 30-year retrospective study. Middle East Afr J Ophthalmol. 2015;22(2):230-2.
  • 12. Yu SS, Zhao Y, Zhao H, Lin JY, Tang X. A retrospective study of 2228 cases with eyelid tumors. Int J Ophthalmol. 2018;11(11):1835-41.
  • 13. Kaliki S, Bothra N, Bejjanki KM, Nayak A, Ramappa G, Mohamed A et al. Malignant eyelid tumors in India: A Study of 536 Asian Indian Patients. Ocul Oncol Pathol. 2019;5(3):210-9.
  • 14. De Potter P, Disneur D, Levecq L, Snyers B. Ocular manifestations of cancer. J Fr Ophtalmol. 2002;25(2):194-202.
  • 15. Burgic M, Iljazovic E, Vodencarevic AN, Burgic M, Rifatbegovic A, Mujkanovic A et al. Clinical characteristics and outcome of malignant eyelid tumors: A five-year retrospective study. Med Arch. 2019;73(3):209-12.
There are 15 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Sibel Özdoğan 0000-0001-5216-008X

Publication Date August 31, 2022
Submission Date March 31, 2022
Published in Issue Year 2022 Volume: 24 Issue: 2

Cite

APA Özdoğan, S. (2022). EVALUATION OF THE EYELID AND PERIOCULAR TUMORS. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 24(2), 357-364. https://doi.org/10.24938/kutfd.1096679
AMA Özdoğan S. EVALUATION OF THE EYELID AND PERIOCULAR TUMORS. Kırıkkale Uni Med J. August 2022;24(2):357-364. doi:10.24938/kutfd.1096679
Chicago Özdoğan, Sibel. “EVALUATION OF THE EYELID AND PERIOCULAR TUMORS”. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 24, no. 2 (August 2022): 357-64. https://doi.org/10.24938/kutfd.1096679.
EndNote Özdoğan S (August 1, 2022) EVALUATION OF THE EYELID AND PERIOCULAR TUMORS. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 24 2 357–364.
IEEE S. Özdoğan, “EVALUATION OF THE EYELID AND PERIOCULAR TUMORS”, Kırıkkale Uni Med J, vol. 24, no. 2, pp. 357–364, 2022, doi: 10.24938/kutfd.1096679.
ISNAD Özdoğan, Sibel. “EVALUATION OF THE EYELID AND PERIOCULAR TUMORS”. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 24/2 (August 2022), 357-364. https://doi.org/10.24938/kutfd.1096679.
JAMA Özdoğan S. EVALUATION OF THE EYELID AND PERIOCULAR TUMORS. Kırıkkale Uni Med J. 2022;24:357–364.
MLA Özdoğan, Sibel. “EVALUATION OF THE EYELID AND PERIOCULAR TUMORS”. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, vol. 24, no. 2, 2022, pp. 357-64, doi:10.24938/kutfd.1096679.
Vancouver Özdoğan S. EVALUATION OF THE EYELID AND PERIOCULAR TUMORS. Kırıkkale Uni Med J. 2022;24(2):357-64.

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