Case Report

Testicular Necrosis Following Orchitis in a Rabbit: A Case Report

Volume: 18 Number: 3 October 3, 2025
TR EN

Testicular Necrosis Following Orchitis in a Rabbit: A Case Report

Abstract

This case report presents a rare clinical presentation of testicular necrosis associated with orchitis and funiculitis in a 9-year-old intact male Holland Lop rabbit. The rabbit was presented to the Animal Hospital of Bursa Uludağ University with bilateral scrotal swelling, pain, erythema, and multiple perineal abscesses. Ultrasonographic examination revealed marked testicular enlargement, heterogeneity, and hydrocele. Despite initial antimicrobial and anti-inflammatory therapy, inflammation extended to the spermatic cord. Bilateral orchiectomy was performed using the closed castration (scrotal ablation) method after stabilization. Histopathology confirmed necrosis in the left testis, chronic orchitis in the right testis, and severe funiculitis. The rabbit recovered uneventfully and remained asymptomatic during five months of follow-up. The animal died 15 months postoperatively due to multiple organ failure secondary to age-related complications. This case emphasizes the importance of timely surgical intervention in progressive testicular infections to prevent irreversible tissue damage.

Keywords

Ethical Statement

Ethics Committee Information: This study does not fall under the scope requiring HADYEK approval, as outlined in Article 8(k) of the “Regulation on the Working Procedures and Principles of Animal Experiments Ethics Committees.” All data, findings, and materials presented in this report were obtained in compliance with academic integrity and ethical standards.

References

  1. Bertram, C. A., Bertram, B., Bartel, A., Ewringmann, A., Fragoso-Garcia, M. A., Erickson, N. A., ... & Klopfleisch, R. (2021). Neoplasia and tumor-like lesions in pet rabbits (Oryctolagus cuniculus): a retrospective analysis of cases between 1995 and 2019. Veterinary Pathology, 58, 901-911. https://doi.org/10.1177/0300985820973460
  2. College of Veterinary Medicine, University of Missouri. (n.d.). Pasteurellosis in Rabbits (DORA – Diseases of Research Animals). University of Missouri, CVM 【55†】. Retrieved May 2, 2025, from https://cvm.missouri.edu/diseases-of-research-animals-dora/rabbits/pasteurellosis/
  3. Doboși, A. A., Paștiu, A. I., Bel, L. V., Pop, R., Tăbăran, A. F., & Pusta, D. L. (2024). Antemortem and Postmortem Diagnosis of Encephalitozoon cuniculi in a Pet Rabbit (Oryctolagus cuniculus)- A Case Report. Pathogens, 13(12), 1122. https://doi.org/10.3390/pathogens13121122
  4. Espinosa García-San Román, J., Quesada-Canales, Ó., Rosales, R. S., Déniz, S., & Arbelo, M. (2024). Clinicopathologic findings and causes of mortality in 100 pet rabbits from the Canary Islands, Spain, 2011–2022. Journal of Veterinary Diagnostic Investigation, 36(5), 695-700. https://doi.org/10.1177/10406387241264801
  5. Fernández, M., Garcias, B., Duran, I., Molina-López, R. A., & Darwich, L. (2023). Current situation of bacterial infections and antimicrobial resistance profiles in pet rabbits in Spain. Veterinary Sciences, 10(5), 352. https://doi.org/10.3390/vetsci10050352
  6. Heatley, J. J., & Smith, A. N. (2004). Spontaneous neoplasms of lagomorphs. Veterinary Clinics of North America: Exotic Animal Practice, 7, 561-577.
  7. Irizarry-Rovira, A. R., Lennox, A. M., & Ramos-Vara, J. A. (2008). Granular cell tumor in the testis of a rabbit: Cytologic, histologic, immunohistochemical, and electron microscopic characterization. Veterinary Pathology, 4, 73–77. https://doi.org/10.1354/vp.45-1-73
  8. Maxıe, M. G. (Ed.) (2016). Orchitis/Epididymitis. In: Jubb, Kennedy & Palmer’s Pathology of Domestic Animals, 6th edition, Vol. 3. Elsevier, St. Louis.

Details

Primary Language

English

Subjects

Veterinary Surgery

Journal Section

Case Report

Early Pub Date

September 19, 2025

Publication Date

October 3, 2025

Submission Date

July 16, 2025

Acceptance Date

September 3, 2025

Published in Issue

Year 2025 Volume: 18 Number: 3

APA
Ünlü, E. (2025). Testicular Necrosis Following Orchitis in a Rabbit: A Case Report. Kocatepe Veterinary Journal, 18(3), 337-340. https://izlik.org/JA86SW77YS
AMA
1.Ünlü E. Testicular Necrosis Following Orchitis in a Rabbit: A Case Report. kvj. 2025;18(3):337-340. https://izlik.org/JA86SW77YS
Chicago
Ünlü, Elif. 2025. “Testicular Necrosis Following Orchitis in a Rabbit: A Case Report”. Kocatepe Veterinary Journal 18 (3): 337-40. https://izlik.org/JA86SW77YS.
EndNote
Ünlü E (October 1, 2025) Testicular Necrosis Following Orchitis in a Rabbit: A Case Report. Kocatepe Veterinary Journal 18 3 337–340.
IEEE
[1]E. Ünlü, “Testicular Necrosis Following Orchitis in a Rabbit: A Case Report”, kvj, vol. 18, no. 3, pp. 337–340, Oct. 2025, [Online]. Available: https://izlik.org/JA86SW77YS
ISNAD
Ünlü, Elif. “Testicular Necrosis Following Orchitis in a Rabbit: A Case Report”. Kocatepe Veterinary Journal 18/3 (October 1, 2025): 337-340. https://izlik.org/JA86SW77YS.
JAMA
1.Ünlü E. Testicular Necrosis Following Orchitis in a Rabbit: A Case Report. kvj. 2025;18:337–340.
MLA
Ünlü, Elif. “Testicular Necrosis Following Orchitis in a Rabbit: A Case Report”. Kocatepe Veterinary Journal, vol. 18, no. 3, Oct. 2025, pp. 337-40, https://izlik.org/JA86SW77YS.
Vancouver
1.Elif Ünlü. Testicular Necrosis Following Orchitis in a Rabbit: A Case Report. kvj [Internet]. 2025 Oct. 1;18(3):337-40. Available from: https://izlik.org/JA86SW77YS