Bir Tavşanda Orchitis Sonrası Testiküler Nekroz: Olgu Sunumu

Öz

Bu olguda, 9 yaşında, kısırlaştırılmamış erkek Holland Lop ırkı bir tavşanda görülen orchitis ve funiculitis’ e bağlı nadir bir testiküler nekroz vakası sunulmaktadır. Tavşan, Bursa Uludağ Üniversitesi Hayvan Hastanesi’ne bilateral skrotal şişlik, ağrı, eritem ve çok sayıda perineal apse şikayetleriyle getirildi. Ultrasonografik incelemede belirgin testiküler büyüme, heterojenite ve hidrosel tespit edildi. Başlangıçta uygulanan antimikrobiyal ve antiinflamatuar tedaviye rağmen inflamasyon spermatik kordu tutacak şekilde ilerleme gösterdi. Stabilizasyonun ardından, kapalı kastrasyon (skrotal ablasyon) yöntemi ile bilateral orşiektomi uygulandı. Histopatolojik incelemede sol testiste nekroz, sağ testiste kronik orşitis ve şiddetli funikülit saptandı. Tavşan, ameliyat sonrası dönemde komplikasyonsuz şekilde iyileşti ve beş aylık takip sürecinde herhangi bir klinik belirti göstermedi. Operasyondan 15 ay sonra, yaşa bağlı gelişen çoklu organ yetmezliği nedeniyle hayatını kaybetti. Bu olgu, ilerleyici testiküler enfeksiyonlarda geri dönüşümsüz doku hasarını önlemek adına zamanında cerrahi müdahalenin önemini vurgulamaktadır.

Anahtar Kelimeler

• Funiculitis
• Orşiektomi
• Orchitis
• Tavşan
• Testiküler nekroz

Testicular Necrosis Following Orchitis in a Rabbit: A Case Report

Öz

This case report presents a rare clinical presentation of testicular necrosis associated with orchitis and funiculitis in a 9-year-old intact male Holland Lop rabbit. The rabbit was presented to the Animal Hospital of Bursa Uludağ University with bilateral scrotal swelling, pain, erythema, and multiple perineal abscesses. Ultrasonographic examination revealed marked testicular enlargement, heterogeneity, and hydrocele. Despite initial antimicrobial and anti-inflammatory therapy, inflammation extended to the spermatic cord. Bilateral orchiectomy was performed using the closed castration (scrotal ablation) method after stabilization. Histopathology confirmed necrosis in the left testis, chronic orchitis in the right testis, and severe funiculitis. The rabbit recovered uneventfully and remained asymptomatic during five months of follow-up. The animal died 15 months postoperatively due to multiple organ failure secondary to age-related complications. This case emphasizes the importance of timely surgical intervention in progressive testicular infections to prevent irreversible tissue damage.

Anahtar Kelimeler

• Funiculitis
• Orchiectomy
• Orchitis
• Rabbit
• Testicular necrosis

Kaynakça

1. Bertram, C. A., Bertram, B., Bartel, A., Ewringmann, A., Fragoso-Garcia, M. A., Erickson, N. A., ... & Klopfleisch, R. (2021). Neoplasia and tumor-like lesions in pet rabbits (Oryctolagus cuniculus): a retrospective analysis of cases between 1995 and 2019. Veterinary Pathology, 58, 901-911. https://doi.org/10.1177/0300985820973460
2. College of Veterinary Medicine, University of Missouri. (n.d.). Pasteurellosis in Rabbits (DORA – Diseases of Research Animals). University of Missouri, CVM 【55†】. Retrieved May 2, 2025, from https://cvm.missouri.edu/diseases-of-research-animals-dora/rabbits/pasteurellosis/
3. Doboși, A. A., Paștiu, A. I., Bel, L. V., Pop, R., Tăbăran, A. F., & Pusta, D. L. (2024). Antemortem and Postmortem Diagnosis of Encephalitozoon cuniculi in a Pet Rabbit (Oryctolagus cuniculus)- A Case Report. Pathogens, 13(12), 1122. https://doi.org/10.3390/pathogens13121122
4. Espinosa García-San Román, J., Quesada-Canales, Ó., Rosales, R. S., Déniz, S., & Arbelo, M. (2024). Clinicopathologic findings and causes of mortality in 100 pet rabbits from the Canary Islands, Spain, 2011–2022. Journal of Veterinary Diagnostic Investigation, 36(5), 695-700. https://doi.org/10.1177/10406387241264801
5. Fernández, M., Garcias, B., Duran, I., Molina-López, R. A., & Darwich, L. (2023). Current situation of bacterial infections and antimicrobial resistance profiles in pet rabbits in Spain. Veterinary Sciences, 10(5), 352. https://doi.org/10.3390/vetsci10050352
6. Heatley, J. J., & Smith, A. N. (2004). Spontaneous neoplasms of lagomorphs. Veterinary Clinics of North America: Exotic Animal Practice, 7, 561-577.
7. Irizarry-Rovira, A. R., Lennox, A. M., & Ramos-Vara, J. A. (2008). Granular cell tumor in the testis of a rabbit: Cytologic, histologic, immunohistochemical, and electron microscopic characterization. Veterinary Pathology, 4, 73–77. https://doi.org/10.1354/vp.45-1-73
8. Maxıe, M. G. (Ed.) (2016). Orchitis/Epididymitis. In: Jubb, Kennedy & Palmer’s Pathology of Domestic Animals, 6th edition, Vol. 3. Elsevier, St. Louis.

9. Reineking, W., Seehusen, F., Lehmbecker, A., & Wohlsein, P. (2019). Predominance of granular cell tumours among testicular tumours of rabbits (Oryctolagus cuniculi f. dom.). Journal of Comparative Pathology, 173, 24-29. https://doi.org/10.1016/j.jcpa.2019.09.012
10. Sarierler, M., & Kılıç, N. (2003). An overview of patients referred to the University of Adnan Menderes (ADÜ) Faculty of Veterinary Medicine Department of Surgery (1999-2003). https:///doi/full/10.5555/20043098942
11. Suciu, M., Serban, O., Iacob, G., Lucan, C., & Badea, R. (2017). Severe acute epididymo-orchitis complicated with abscess and testicular necrosis–case report. Ultrasound International Open, 3, E46-E48. https://doi.org/10.1055/s-0042-122149
12. Varga, M. (2014). Textbook of Rabbit Medicine (2nd ed.). Elsevier Health Sciences.
13. Zachary, J. F., & McGavin, M. D. (Eds.). (2012). Pathologic Basis of Veterinary Disease5: Pathologic Basis of Veterinary Disease. Elsevier Health Sciences.