Morphology and Volume Measurement of Bursa Fabricius by Stereology in Merlin (Falco Columbarius)

Year 2019, , 27 - 32, 31.03.2019

İsmail Türkmenoğlu , İbrahim Demirkan , Aysun Çevik Demirkan , Murat Sırrı Akosman Mehmet Aydın Akalan

https://doi.org/10.30607/kvj.423748

Abstract

Bursa fabricius
(Bursa cloacalis or Bursa fabricii) is a lymphoepithelial organ of poultry and
serves as the primary lymphoid organ. In addition to the development and
differentiation of Bursa Fabricius B lymphocytes, immunoglobulin is also
responsible for isotype change. Bursa fabricius is also seen as a secondary
lymphoid organ due to the presence of a small T-lymphocyte cluster in the
channel opening to cloaca, but early development of the organ is delayed. In
this study, morphological and stereological examinations were performed on
bursa fabricius obtained from 5 adult Merlin (Falco columbarius). Our
morphological studies have shown that the bursa fabricius of merlin is located
on the cloaca and that it is opened to proctodeum through a canal.  We saw that it was oval shaped and had plums
made by the mucosa layer in the lumen. The size of these structures was found
to be 15,62 ± 1,41 mm, 10.14 ± 0,66 mm in the widest area and  0.98 ± 0,07 mm in the shortest area. The
volume we calculated by the stereological methods was 0.190 ± 0,008 cm³. The morphological structure of
bursa fabricius in merlin was determined and the volume was calculated by
stereological method and it was thought that it might be the source of future
studies in the species differentiation in poultry.

Keywords

bursa fabricius, Falco columbarius, merlin, morphology, stereology

Boz Doğanda (Falco Columbarius) Bursa Fabricius’un Morfolojisi ve Stereolojik Metod ile Hacminin Hesaplanması

Abstract

Bursa fabricius
(Bursa cloacalis veya Bursa fabricii) kanatlıların lenfoepitelial bir organı
olup kanatlıların primer lenfoid organı organı olarak görev yapmaktadır. B
lenfositlerinin gelişim ve farklılaşmasının yanında immunoglobulin izotip
değişminden de sorumludur. Bursa fabricius cloaca’ya açılan kanalında küçük bir
T lenfosit kümesi bulunduğundan dolayı aynı zamanda sekonder lenfoid organ
olarak da görülmektedir ancak erken dönemde organın gelişimi gerilemektedir. Bu
çalışmada 5 adet ergin bozdoğandan (Falco
columbarius) elde edilen bursa fabricius’lar üzerinde morfolojik ve
stereolojik incelemeler yapıldı. Morfolojik incelemeler sonucunda
bozdoğan’larda bursa fabricius’un cloaca üzerinde bulunduğu, bir kanal
vasıtasıyla proctodeum’a açıldığı, şeklinin oval olduğu ve lümeninde mukoza
katmanı tarafından yapılmış plikalar bulunduğu gözlemlendi. Bu yapıların boyu
15,62 ± 1,41 mm, eni en uzun bölgede 10.14 ± 0,66 mm en kısa bölgede ise 0.98 ±
0,07 mm olarak saptandı.  Stereolojik
yöntemle yapılan hesaplamalarda hacmi 0.190 ± 0,008 cm³ olarak
tespit edildi. Bozdoğanda bursa fabricius’un morfolojik yapısı ortaya konarak
stereolojik metotla hacmi hesaplanmış olup, kanatlılarda tür ayrımında ileride
yapılacak çalışmalara kaynak olabileceği düşünüldü.

Keywords

bozdoğan, falco columbarius, bursa fabricius, morfoloji, stereoloji

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