Etiological Treatment of Protozoer Diarrhea in Neonatal Ruminants

Öz

İshal enfeksiyöz ajanların, nutrisyonel ve çevre faktörlerinin de içinde bulunduğu multifaktöriyel bir semptomdur. İshalin önlenmesinde birçok koruma ve tedavi stratejisi geliştirilmesine rağmen ishal ruminantlarda hala en yaygın problemlerin başında gelmektedir. Yeni doğanlarda ve genç ruminantlarda kriptosporidiozis, koksidiyozis ve giardiazis ishale neden olan önemli protozoer hastalıklardır. Neonatal ishallerin semptomatik sağaltımı benzerlik gösterse de etiyolojik sağaltım da farklılıklar bulunmaktadır. Bu derlemede kriptosporidiozis, koksidiyozis ve giardiazis’in tedavisinde kullanılan antiprotozoer ilaçlardan bahsedilmektedir.

Anahtar Kelimeler

• Diarrhea,ruminant,cryptosporidiosis,coccidiosis

Kaynakça

1. Referans1 Özkan C, Akgül Y. Neonatal İshalli Buzağılarda Hematolojik,Biyokimyasal ve Elektrokardiyografik Bulgular. Yüzüncü Yıl Üniversitesi Vet Fakültesi Derg. 2004;15(1):123–9.
2. Referans2 Savaş T. Oğlak Büyütme: Sorunlu Noktalar Üzerinde Bir Değerlendirme. 2007;48(1):44–53.
3. Referans3 Aydoğdu U. Kuzularda Neonatal Mortalite. Cumhuriyet Üniv Sağ Bil Enst Derg. 2016;2(1):37-46.
4. Referans4 Altuğ N, Yüksek N, Özkan C, Keleş İ, Başbuğan Y. Neonatal Buzağı İshallerinin İmmunokromotografik Test Kitleri İle Hızlı Etiyolojik Teşhisi. YYU Vet Fak Derg. 2013;24(3):123–8.
5. Refarans5 Göz Y, Altuǧ N, Yüksek N, Özkan C. Parasites detected in neonatal and young calves with diarrhoea. Bull Vet Inst Pulawy. 2006;50(3):345–8.
6. Refarans6 Ozdal N, Tanritanir P, Goz Y, Deger S, Kozat S. Parasitic protozoans (Eimeria, Giardia, and Cryptosporidium) in lambs with diarrhoea in the van province (Turkey). Bull Vet Inst Pulawy. 2009;53(1):47–51.
7. Referans7 Al M, Balıkçı E. Neonatal ishalli buzağılarda rotavirus, coronavirus, E. coli K99 ve Cryptosporidium parvum’un hızlı test kitleri ile teşhisi ve enteropatojen ile maternal immünite ilişkisi. FÜ Sağ Bil Vet Derg. 2012;26(2):73–8.
8. Referans8 Sahinduran, S. Protozoan diseases in farm ruminants. In A Bird'sEye View of Veterinary Medicine. 2012. In Tech. Available from: http://www.intechopen.com/books/a-bird-s-eye-view-of-veterinary-medicine/protozoan-diseases-in-farmruminants

9. Referans9 Sevinç F. Ruminantlarda Cryptosporidiosis. Vet Bil Deg. 2004;4:79-84.
10. Referans10 Shahiduzzaman M, Daugschies A. Therapy and prevention of cryptosporidiosis in animals. Vet Parasitol. 2012;188(3–4):203–14.
11. Referans11 O’Handley RM, Olson ME. Giardiasis and Cryptosporidiosis in Ruminants. Vet Clin North Am - Food Anim Pract. 2006;22(3):623–643.
12. Referans12 Gargala G. Drug treatment and novel drug target against Cryptosporidium. Parasite. 2008;15(3):275–281.
13. Referans13 Chartier C, Mallereau M-P, Naciri M. Prophylaxis using paromomycin of natural cryptosporidial infection in neonatal kids. Prev Vet Med. 1996;25(3–4):357–361.
14. Referans14 Fayer R, Ellis W. Paromomycin is effective as prophylaxis for cryptosporidiosis in dairy calves. J Parasitol. 1993;79(5):771–774.
15. Referans15 Grinberg A, Lopez-Villalobos N, Markovics A, Kosak A, Galindez J, Tranquillo VM. Controlling the onset of natural cryptosporidiosis in calves with paromomycin sulphate. Vet Rec. 2002;151(20):606–608.
16. Referans16 Viu M, Quılez J, Sánchez-Acedo C, Del Cacho E, López-Bernad F. Field trial on the therapeutic efficacy of paromomycin on natural Cryptosporidium parvum infections in lambs. Vet Parasitol. 2000;90(3):163–170.
17. Referans17 Najdrowski M, Heckeroth AR, Wackwitz C, Gawlowska S, Mackenstedt U, Kliemt D, et al. Development and validation of a cell culture based assay for in vitro assessment of anticryptosporidial compounds. Parasitol Res. 2007;101(1):161–167.
18. Referans18 Jarvie BD, Trotz-Williams LA, McKnight DR, Leslie KE, Wallace MM, Todd CG, et al. Effect of halofuginone lactate on the occurrence of Cryptosporidium parvum and growth of neonatal dairy calves. J Dairy Sci. 2005;88(5):1801–1806.
19. Referans19 Giadinis ND, Papadopoulos E, Panousis N, Papazahariadou M, Lafi SQ, Karatzias H. Effect of halofuginone lactate on treatment and prevention of lamb cryptosporidiosis: An extensive field trial. J Vet Pharmacol Ther. 2007;30(6):578–582.
20. Referans20 Lefay D, Naciri M, Poirier P, Chermette R. Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in suckling calves. Vet Rec. 2001;148(4):108–112.
21. Referans21 Naciri M, Mancassola R, Yvoré P, Peeters JE. The effect of halofuginone lactate on experimental Cryptosporidium parvum infections in calves. Vet Parasitol. 1993;45(3–4):199–207.
22. Referans22 Trotz-Williams LA, Jarvie BD, Peregrine AS, Duffield TF, Leslie KE. Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in dairy calves. Vet Rec. 2011;168(19):509.
23. Referans23 Lindsay DS, Woods KM, Upton SJ, Blagburn BL. Activity of decoquinate against Cryptosporidium parvum in cell cultures and neonatal mice. Vet Parasitol. 2000;89(4):307–311.
24. Referans24 Moore DA, Atwill ER, Kirk JH, Brahmbhatt D, Alonso LH, Hou L, et al. Prophylactic use of decoquinate for infections with Cryptosporidium parvum in experimentally challenged neonatal calves. J Am Vet Med Assoc. 2003;223(6):839–845.
25. Referans25 Lallemond M, Villeneuve A, Belda J, Dubreuil P. Field study of the efficacy of halofuginone and decoquinate in the treatment of crytosporidiosis in veal calves. Vet Rec. 2006;159(20):672–677.
26. Referans26 Naguleswaran A, Alaeddine F, Guionaud C, Vonlaufen N, Sonda S, Jenoe P, et al. Neospora caninum protein disulfide isomerase is involved in tachyzoite-host cell interaction. Int J Parasitol. 2005;35(13):1459–1472.
27. Referans27 Schnyder M, Kohler L, Hemphill A, Deplazes P. Prophylactic and therapeutic efficacy of nitazoxanide against Cryptosporidium parvum in experimentally challenged neonatal calves. Vet Parasitol. 2009;160(1–2):149–154.
28. Referans28 Ollivett TL, Nydam D V., Bowman DD, Zambriski JA, Bellosa ML, Linden TC, et al. Effect of nitazoxanide on cryptosporidiosis in experimentally infected neonatal dairy calves. J Dairy Sci. 2009;92(4):1643–1648.
29. Referans29 Elitok B, Elitok ÖM, Pulat H. Efficacy of azithromycin dihydrate in treatment of cryptosporidiosis in naturally infected dairy calves. J Vet Intern Med. 2005;19(4):590–593.
30. Referans30 Paraud C, Pors I, Journal JP, Besnier P, Reisdorffer L, Chartier C. Control of cryptosporidiosis in neonatal goat kids: Efficacy of a product containing activated charcoal and wood vinegar liquid (Obionekk®) in field conditions. Vet Parasitol. 2011;180(3–4):354–357.
31. Referans31 Watarai S, Tana, Koiwa M. Feeding activated charcoal from bark containing wood vinegar liquid (Nekka-Rich) is effective as treatment for cryptosporidiosis in calves. J Dairy Sci. 2008;91(4):1458–1463.
32. Referans32 Hunt E, Fu Q, Armstrong MU, Rennix DK, Webster DW, Galanko JA, et al. Oral bovine serum concentrate improves cryptosporidial enteritis in calves. Pediatr Res. 2002;51(3):370–376.
33. Referans33 Chartier C, Paraud C. Coccidiosis due to Eimeria in sheep and goats, a review. Small Rumin Res. 2012;103(1):84–92.
34. Referans34 Jolley WR, Bardsley KD. Ruminant Coccidiosis. Vet Clin North Am - Food Anim Pract. 2006;22(3):613–621.
35. Referans35 Mundt HC, Bangoura B, Mengel H, Keidel J, Daugschies A. Control of clinical coccidiosis of calves due to Eimeria bovis and Eimeria zuernii with toltrazuril under field conditions. Parasitol Res. 2005;97:134-142.
36. Referans36 Daugschies A, Najdrowski M. Eimeriosis in cattle: Current understanding. J Vet Med Ser B Infect Dis Vet Public Heal. 2005;52(10):417–427.
37. Referans37 Aksoy G, Kurtdede A, Gül Y, Ağaoğlu TZ, Dodurka T, Akgül Y, Kaymaz Akdoğan A, Kalınbacak A, Or E, Keleş İ, Bakırel U, Erdoğan MH, Çitil M, İssi M. Geviş Getiren Hayvanların İç Hastalıkları. In: Gül Y, editör. 3. Baskı. Malatya: Medipres Matbaacılık; 2012. s:144-148.
38. Referans38 Engidaw S, Anteneh M, Demis C. Coccidiosis in Small Ruminants. African J Basic Appl Sci. 2015;7(6):311–319.
39. Referans39 Radostits OM, Gay CC, Hinchcliff KW, Constable PD. Veterinary Medicine A textbook of the diseases of cattle, horses, sheep, pigs and goats. 10th edition, W.B. Saunders Co; 2008. p: 1483-1540.
40. Referans40 Mundt HC, Daugschies A, Uebe F, Rinke M. Efficacy of toltrazuril against artificial infections with Eimeria bovis in calves. Parasitol Res. 2003;90(3):166–167.
41. Referans41 Geurden T, Vercruysse J, Claerebout E. Is Giardia a significant pathogen in production animals? Exp Parasitol. 2010;124(1):98–106.
42. Referans42 Ural K, Aysul N, Voyvoda H, Ulutas B, Aldemir OS, Eren H. Single dose of secnidazole treatment against naturally occuring Giardia duodenalis infection in Sakiz lambs. Rev MVZ Córdoba. 2014;19(1):4023–4032.
43. Referans43 Volpato A, Fortuoso BF, Campigotto G, Glombowsky P, Bottari NB, Lopes LS, et al. Secnidazole for control of giardiasis in dairy calves. Exp Parasitol. 2018;189:16–18.
44. Referans44 Toros G, Ural K. Single dose secnidazole treatment efficiency against naturally occuring Giardia duodenalis infection in calves. Rev MVZ Córdoba. 2018;23(2):6660–6670.
45. Referans45 Edlind TD, Hang TL, Chakraborty PR. Activity of the anthelmintic benzimidazoles against Giardia lamblia in vitro. J Infect Dis. 1990;162(6):1408–14011.
46. Referans46 Meloni BP, Thompson RCA, Reynoldson JA, Seville P. Albendazole: a more effective antigiardial agent in vitro than metronidazole or tinidazole. Trans R Soc Trop Med Hyg. 1990;84(3):375–379.
47. Referans47 O’Handley RM, Olson ME, McAllister TA, Morck DW, Jelinski M, Royan G, et al. Efficacy of fenbendazole for treatment of giardiasis in calves. Am J Vet Res. 1997;58(4):384–388.
48. Referans48 Xiao L, Saeed K, Herd RP. Efficacy of albendazole and fenbendazole against Giardia infection in cattle. Vet Parasitol. 1996;61(1–2):165–170.
49. Referans49 O’Handley RM, Cockwill C, Jelinski M, McAllister TA, Olson ME. Effects of repeat fenbendazole treatment in dairy calves with giardiosis on cyst excretion, clinical signs and production. Vet Parasitol. 2000;89(3):209–218.
50. Referans50 Albay MK, Sahinduran S, Adanir R, Yukari BA, Kose O. Doǧal i̇nfekte giardiazisli kuzuların tedavisinde albendazol ve i̇ki farklı paromomisin dozunun etkisinin karşılaştırılması. Kafkas Univ Vet Fak Derg. 2011;17(6):1021–1024.