Abstract
Molecular studies have come to the fore within the scope of the
development of animal breeding. For this reason, genetic studies made or will
be made on production and quality of hair in animals have become more of an
issue. In animals like goat and sheep been rich in terms of textile products, hair
structure is constitutively divided into two as primary and secondary. In studies
made in these follicles, it is identified that the 10077 genes are expressed in
the primary hair follicles and the 7772 genes are expressed in the secondary hair
follicles. In this review, it will be summarized the anatomy and the process of
development of the hair follicle generating the animal fibers, genes had an
effect upon development of hair and the processes formed the hair follicle of
these genes. In addition, it will be mentioned about structure of hair follicle
and efficiency of genes; morphogenesis and cycle stages; anagen, catagen and
telogen. The scope of this work includes examination of genes associated with
quality from the formation of hair follicle to starting of first cycle and in
the repetition of process continually.
Keywords
References
- Alonso L, Fuchs E. The hair cycle. Journal of Cell Science. 2006; 119: 391-393.
- Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell. 2004; 118(5): 635-648.
- Blume-Peytavi U, Tosti A, Whiting DA, Trüeb RM. Hair growth and disoders. Springer, Berlin Heidelberg; 2008.
- Botchkarev VA, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G, McMahon JA, Peters C, Lauster R. Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nature Cell Biology. 1999; 1: 158-164.
- Bray SJ. Notch signalling: A simple pathway becomes complex. Nature Reviews Molecular Cell Biology. 2006; 7: 678-689.
- Chen D, Jarrell A, Guo C, Lang R, Atit R. Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development. 2012; 139: 1522-1533.
- Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL. Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Developmental Cell. 2012; 23: 981-994.
- Demirtas H., 2013. (http://www.veteriner.cc/keci/keci_kili.asp). Keçi kılından elde edilen ürünler. Erişim Tarihi: 23.06.2015.
- Dong Y, Xie M, Jiang Y, Xiao N, Du X, Zhang W, Tosser-Klopp G, Wang J, Yang S, Liang J, Chen W, Chen J, Zeng P, Hou Y, Bian C, Pan S, Li Y, Liu X, Wang W, Servin B, Sayre B, Zhu B, Sweeney D, Moore R, Nie W, Shen Y, Zhao R, Zhang G, Li J, Faraut T, Womack J, Zhang Y, Kijas J, Cockett N, Xu X, Zhao S, Wang J, Wang W. Sequencing and automated whole-genome optical mapping of the genome of a domestic goat (Capra hircus). Nature Biotechnology. 2013; 31: 135-141.
Abstract
Hayvan ırkların
geliştirilmesi kapsamında moleküler çalışmalar ön plana çıkmaktadır. Bu nedenle
hayvanlarda kıl üretimi ve kalitesi üzerine yapılan ve yapılacak olan genetik
çalışmalar önem kazanmıştır. Keçi ve koyun gibi tekstil ürünleri açısından değerli
hayvanlarda, kıl yapısı temel olarak primer ve sekonder olmak üzere ikiye
ayrılmaktadır. Bu foliküllerle yapılan çalışmalarda primer foliküllerde 10077
genin, sekonder foliküllerde ise 7772 genin ifade edildiği tespit edilmiştir. Bu
derlemede, hayvansal lifleri oluşturan kıl folikülünün anatomisi ve gelişim
süreci, kıl gelişimine etki eden önemli genler ve bu genlerin, kıl folikülünü şekillendirme
süreçleri özetlenecektir. Buna ek olarak kıl folikülünün yapısı, morfogenezi ve siklusun meydana geldiği
anajen, katajen ve telojen aşamaları ve bu aşamalardaki genlerin etkinliğinden
bahsedilecektir. Çalışmanın kapsamı; kıl folikülünün oluşumundan ilk siklusun
başlamasına ve sürecin devamlı olarak tekrarında kalite ile ilişkilendirilmiş
genlerin incelenmesini içermektedir.
Keywords
References
- Alonso L, Fuchs E. The hair cycle. Journal of Cell Science. 2006; 119: 391-393.
- Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell. 2004; 118(5): 635-648.
- Blume-Peytavi U, Tosti A, Whiting DA, Trüeb RM. Hair growth and disoders. Springer, Berlin Heidelberg; 2008.
- Botchkarev VA, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G, McMahon JA, Peters C, Lauster R. Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nature Cell Biology. 1999; 1: 158-164.
- Bray SJ. Notch signalling: A simple pathway becomes complex. Nature Reviews Molecular Cell Biology. 2006; 7: 678-689.
- Chen D, Jarrell A, Guo C, Lang R, Atit R. Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development. 2012; 139: 1522-1533.
- Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL. Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Developmental Cell. 2012; 23: 981-994.
- Demirtas H., 2013. (http://www.veteriner.cc/keci/keci_kili.asp). Keçi kılından elde edilen ürünler. Erişim Tarihi: 23.06.2015.
- Dong Y, Xie M, Jiang Y, Xiao N, Du X, Zhang W, Tosser-Klopp G, Wang J, Yang S, Liang J, Chen W, Chen J, Zeng P, Hou Y, Bian C, Pan S, Li Y, Liu X, Wang W, Servin B, Sayre B, Zhu B, Sweeney D, Moore R, Nie W, Shen Y, Zhao R, Zhang G, Li J, Faraut T, Womack J, Zhang Y, Kijas J, Cockett N, Xu X, Zhao S, Wang J, Wang W. Sequencing and automated whole-genome optical mapping of the genome of a domestic goat (Capra hircus). Nature Biotechnology. 2013; 31: 135-141.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Reviews |
| Authors | |
| Publication Date | September 13, 2017 |
| Submission Date | February 2, 2017 |
| Published in Issue | Year 2017 Volume: 2 Issue: 1 |
