Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves

Year 2019, Volume: 4 Issue: 1, 37 - 40, 30.06.2019

Zafer Usta , Ottmar Dıstl

https://doi.org/10.24880/maeuvfd.492354

Abstract

A two-days-old female German Holstein twin calf borned a deformed
cranium. The calf was not able to endure and died shortly after the clinical
examination and this calf was submitted to necropsy. Pathological-anatomical
examination showed multiple malformations including hydrocephalus internus and
atrophy of cerebellar hemispheres, hypoplasia of the cerebellum, syringomyelia
in the cervical spinal cord and the cranial part of the thoracic spinal cord,
hydromyelia in the caudal part of the thoracic spinal cord, scoliosis between
the fifth and seventh thoracic vertebra and bilateral keratitis could be
associated with a positive result for bovine viral diarrhoea (BVD) virus
antibodies. Its male co-twin with brachyury and also dam of the twins were
positive for BVD virus antibodies by ELİSA Test. Infection by BVD virus in an
early stage of the pregnancy may be assumed to be responsible for the multiple
malformations in the female twin and the brachyury of the male co-twin.

Keywords

Bovine Virus Diarrhoea, Brachyury, Holstein, Hydrocephalus, twin

İkiz Alman Holştayn Buzağıda Hidrosefali Internus, Diğer Sinirsel Malformasyonlar ve Kısa Kuyrukluluk Olgusu

Abstract

İki günlük Alman Holştayn Buzağı deforma bir kafa şekli ile doğdu. Buzağı,
klinik muayeneden kısa süre sonra dayanamadı ve öldü ve daha sonra nekropsiye
verildi. Yapılan Patolojik-Anatomik inceleme neticesinde hidrosefali internus ve serebellar hemisferlerin atrofisi,
serebellum hipoplazisi, servikal omurilikte siringomiyeli ve torasik omuriliğin
kraniyal kısmı dâhil olmak üzere çoklu şekil bozuklukları, torasik spinal
kordonun kaudal kısmında hidromyeli, beşinci ve yedinci torakal vertebra
arasında görülen skolyoz ve bilateral keratitis görülen ikiz doğan iki günlük bir Alman Holştayn buzağıda
bovine viral diyare (BVD) virüsü antikorları pozitif çıkan bu sonuç görülen
anomaliler ile ilişkili olabiliceği kanısına varıldı. Brachyury (kısa kuyruk) ile karakterize diğer erkek buzağıda ve
ikiz buzağıların annesi olan inekde yapılan ELISA testi neticesinde BVD virüs antikorları
için pozitif olarak tespit edildi. BVD virüsünün gebeliğin erken evresindeki
enfeksiyonu, dişi buzağının çoklu malformasyonundan ve erkek buzağıda
brachury’sinden sorumlu olduğu varsayılabilir.

Keywords

Bovine Viral Diyare, Brachyury, Hidrosefali, Holştayn, İkizlik

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